3-Brom-2-fluor-5-methylphenylborons\\\\u00E4ure
Artikel-Nr:
(BOSSBS-15486R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15486R-A555
Lokale Artikelnummer::
BOSSBS-15486R-A555
Beschreibung:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of Zinc-finger proteins contain a Kr_ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. HIC-2 (hypermethylated in cancer 2) possesses Zinc finger motifs that are thought to be important for DNA-binding and also has a BTB/POZ domain at the N-terminus, which is thought to be important for protein-protein binding, as well as for the binding of transcription factors. HIC-2 is also known as Hic-3, HIC1-related gene on chromosome 22 or Zinc finger and BTB domain-containing protein 30, and is a 615 amino acid protein that is expressed as two isoforms produced by alternative splicing. HIC-2 is highly expressed in cerebellum and is localised to the nucleus in cells. HIC-2 contains a short amino acid sequence that is thought to interact with CtBP, a transcriptional repressor. The gene sequence associated with HIC-2 is thought to be a target for miRNAs (microRNAs) which are expressed in many cancers, suggesting that HIC-2 could possess tumor suppressor capabilities.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15486R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15486R-A750
Lokale Artikelnummer::
BOSSBS-15486R-A750
Beschreibung:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of Zinc-finger proteins contain a Kr_ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. HIC-2 (hypermethylated in cancer 2) possesses Zinc finger motifs that are thought to be important for DNA-binding and also has a BTB/POZ domain at the N-terminus, which is thought to be important for protein-protein binding, as well as for the binding of transcription factors. HIC-2 is also known as Hic-3, HIC1-related gene on chromosome 22 or Zinc finger and BTB domain-containing protein 30, and is a 615 amino acid protein that is expressed as two isoforms produced by alternative splicing. HIC-2 is highly expressed in cerebellum and is localised to the nucleus in cells. HIC-2 contains a short amino acid sequence that is thought to interact with CtBP, a transcriptional repressor. The gene sequence associated with HIC-2 is thought to be a target for miRNAs (microRNAs) which are expressed in many cancers, suggesting that HIC-2 could possess tumor suppressor capabilities.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15486R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15486R-CY7
Lokale Artikelnummer::
BOSSBS-15486R-CY7
Beschreibung:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of Zinc-finger proteins contain a Kr_ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. HIC-2 (hypermethylated in cancer 2) possesses Zinc finger motifs that are thought to be important for DNA-binding and also has a BTB/POZ domain at the N-terminus, which is thought to be important for protein-protein binding, as well as for the binding of transcription factors. HIC-2 is also known as Hic-3, HIC1-related gene on chromosome 22 or Zinc finger and BTB domain-containing protein 30, and is a 615 amino acid protein that is expressed as two isoforms produced by alternative splicing. HIC-2 is highly expressed in cerebellum and is localised to the nucleus in cells. HIC-2 contains a short amino acid sequence that is thought to interact with CtBP, a transcriptional repressor. The gene sequence associated with HIC-2 is thought to be a target for miRNAs (microRNAs) which are expressed in many cancers, suggesting that HIC-2 could possess tumor suppressor capabilities.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15486R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15486R-A680
Lokale Artikelnummer::
BOSSBS-15486R-A680
Beschreibung:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of Zinc-finger proteins contain a Kr_ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. HIC-2 (hypermethylated in cancer 2) possesses Zinc finger motifs that are thought to be important for DNA-binding and also has a BTB/POZ domain at the N-terminus, which is thought to be important for protein-protein binding, as well as for the binding of transcription factors. HIC-2 is also known as Hic-3, HIC1-related gene on chromosome 22 or Zinc finger and BTB domain-containing protein 30, and is a 615 amino acid protein that is expressed as two isoforms produced by alternative splicing. HIC-2 is highly expressed in cerebellum and is localised to the nucleus in cells. HIC-2 contains a short amino acid sequence that is thought to interact with CtBP, a transcriptional repressor. The gene sequence associated with HIC-2 is thought to be a target for miRNAs (microRNAs) which are expressed in many cancers, suggesting that HIC-2 could possess tumor suppressor capabilities.
VE:
1 * 100 µl
Lieferant:
Sigma-Aldrich
Beschreibung:
Iminodiessigsäure, Sigma-Aldrich®
Artikel-Nr:
(394111-100)
Lieferant:
Merck Millipore (Calbiochem)
Hersteller-Artikelnummer::
394111-100
Lokale Artikelnummer::
CALB394111-100
Beschreibung:
BIS-TRIS-Propan, Millipore®
VE:
1 * 100 g
Artikel-Nr:
(BSENR-114-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-114-100
Lokale Artikelnummer::
BSENR-114-100
Beschreibung:
FUNCTION: Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. These substrates include SYT11, CCNE1, GPR37, STUB1, a 22 kDa O-linked glycosylated isoform of SNCAIP and SEPT5. May play a more general role in the ubiquitin proteasomal pathway by participating in the removal and/or detoxification of abnormally folded or damaged protein. Loss of this ubiquitin ligase activity appears to be the mechanism underlying pathogenesis of PARK2. May protect neurons against alpha synuclein toxicity, proteasomal dysfunction, GPR37 accumulation, and kainate-induced excitotoxicity. May play a role in controlling neurotransmitter trafficking at the presynaptic terminal and in calcium-dependent exocytosis. Regulates cyclin E during neuronal apoptosis. May represent a tumor suppressor gene. SUBCELLULAR LOCATION: Cytoplasm. Co-localizes with STY11 in neutrites. Co-localizes with SNCAIP in brainstem Lewy bodies. TISSUE SPECIFICITY: Highly expressed in the brain including the substantia nigra. Expressed in heart, testis and skeletal muscle. Expression is down-regulated or absent in tumor biopsies, and absent in the brain of PARK2 patients. Overexpression protects dopamine neurons from kainate-mediated apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(FLUO022448-1G)
Lieferant:
FLUOROCHEM
Hersteller-Artikelnummer::
022448-1G
Lokale Artikelnummer::
FLUO022448-1G
Beschreibung:
4-Methoxy-3'-methylbenzhydrol
VE:
1 * 1 g
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Artikel-Nr:
(SARS83.1840.001)
Lieferant:
SARSTEDT
Hersteller-Artikelnummer::
83.1840.001
Lokale Artikelnummer::
SARS83.1840.001
Beschreibung:
Coverslips for cell culture.
VE:
1 * 200 ST
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Lieferant:
hünersdorff GmbH
Beschreibung:
Made of fracture-proof and food-safe polyethylene with sleeve connection for a hose.
Artikel-Nr:
(ABNOMAB5830)
Lieferant:
Abnova
Hersteller-Artikelnummer::
MAB5830
Lokale Artikelnummer::
ABNOMAB5830
Beschreibung:
Mouse monoclonal antibody raised against native H-2Kk.
VE:
1 * 500 µG
Artikel-Nr:
(MOLE32742152-1KG)
Lieferant:
Molekula
Hersteller-Artikelnummer::
32742152-1KG
Lokale Artikelnummer::
MOLE32742152-1KG
Beschreibung:
Dichloressigsäure
VE:
1 * 1 kg
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Artikel-Nr:
(HONC34942-18L)
Lieferant:
Honeywell Chemicals
Hersteller-Artikelnummer::
34942-18L
Lokale Artikelnummer::
HONC34942-18L
Beschreibung:
Diethylether, getrocknet (max. 0.0075% H₂O) stabilisiert, Puriss. p.a. ACS, Riedel-de Haën™
VE:
1 * 18 L
Artikel-Nr:
(EHERC12782100)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C12782100
Lokale Artikelnummer::
EHERC12782100
Beschreibung:
2,6-Dinitroanilin
VE:
1 * 0,1 g
Artikel-Nr:
(231-1075)
Lieferant:
BOCHEM
Hersteller-Artikelnummer::
3493
Lokale Artikelnummer::
BOCH3493
Beschreibung:
Edelstahlklinge, mit Holzgriff.
VE:
1 * 1 ST
Lieferant:
FLUOROCHEM
Beschreibung:
2,3,6-Trifluorbenzamid
Preis auf Anfrage
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