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Bis(3-fluorphenyl)disulfid
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Bis(3-fluorphenyl)disulfid
Artikel-Nr:
(PRSI91-669)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-669
Lokale Artikelnummer::
PRSI91-669
Beschreibung:
Trefoil Factor 2 (TFF2) is a member of the trefoil family and contains two P-type (trefoil) domains. Members of this family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. TFF2 is a secreted protein and specifically expressed in the stomach. TFF2 inhibits gastrointestinal motility and gastric acid secretion. TFF2 could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains.
VE:
1 * 50 µG
Lieferant:
MP Biomedicals
Beschreibung:
Dithioerythritol is an erythro isomer of 2,3-dihydroxy-1,4-dithiolbutane, and an isomer of 1,4-dithiothreitol which is a reagent for maintaining thiols in the reduced state; prevents oxidation of sulfhydryl-containing proteins during SDS-polyacrylamide gel electrophoresis. It also quantitatively reduces disulfides.
Artikel-Nr:
(PRSI26-045)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-045
Lokale Artikelnummer::
PRSI26-045
Beschreibung:
PI3 is an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria. PI3 contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. PI3 belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.This gene encodes an elastase-specific inhibitor, which contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI26-901)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-901
Lokale Artikelnummer::
PRSI26-901
Beschreibung:
Fibromodulin is a member of a family of small interstitial proteoglycans, containing a central region composed of leucine-rich repeats with 4 keratan sulfate chains flanked by disulfide-bonded terminal domains. It may participate in the assembly of the extracellular matrix as it interacts with type I and type II collagen fibrils and inhibits fibrillogenesis in vitro. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix.Fibromodulin is a member of a family of small interstitial proteoglycans, containing a central region composed of leucine-rich repeats with 4 keratan sulfate chains flanked by disulfide-bonded terminal domains. It may participate in the assembly of the extracellular matrix as it interacts with type I and type II collagen fibrils and inhibits fibrillogenesis in vitro. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI38-135)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
38-135
Lokale Artikelnummer::
PRSI38-135
Beschreibung:
BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI38-232)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
38-232
Lokale Artikelnummer::
PRSI38-232
Beschreibung:
BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair.
VE:
1 * 500 µG
Lieferant:
Sigma-Aldrich
Beschreibung:
2,2'-Dipyridyldisulfid, Sigma-Aldrich®
Lieferant:
Thermo Scientific
Beschreibung:
Thermo Scientific EZ-Link Sulfo-NHS-SS-Biotin is a water-soluble, NHS-ester biotinylation reagent whose spacer arm includes a cleavable disulfide bond for reversible labeling of proteins and cell surface primary amines.
Artikel-Nr:
(PRSI96-411)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-411
Lokale Artikelnummer::
PRSI96-411
Beschreibung:
Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.
VE:
1 * 200 µG
Artikel-Nr:
(PRSI91-898)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-898
Lokale Artikelnummer::
PRSI91-898
Beschreibung:
Mouse Cathepsin L is a lysosomal cysteine proteinase which is a member of the peptidase C1 family. This protein is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Cathepsin L plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. Cathepsin L has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI40-213)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
40-213
Lokale Artikelnummer::
PRSI40-213
Beschreibung:
Activin A is a TGF-β family member that exhibits a wide range of biological activities including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in post-menopausal woman have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-β antagonist, Follistatin. Human Activin A is a 26.0 kDa disulfide-linked homodimer of two β A chains, each containing 116 amino acid residues.
VE:
1 * 2 µG
Artikel-Nr:
(PRSI76-815)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-815
Lokale Artikelnummer::
PRSI76-815
Beschreibung:
The FN50 monoclonal antibody specifically reacts with human CD69, the 27 to 33 kDa type II transmembrane protein also known as the very early activation antigen (VEA) or the activation inducer molecule (AIM). It is expressed as a disulfide-linked dimer on B cells, T cells, NK cells, platelets, eosinophils, and neutrophils. It increases in expression upon cell activation and seems to serve a role as a signaling receptor.
VE:
1 * 100 Tests
New Product
Artikel-Nr:
(PRSI40-544)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
40-544
Lokale Artikelnummer::
PRSI40-544
Beschreibung:
Activin A is a TGF-β family member that exhibits a wide range of biological activities including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in postmenopausal women have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-β antagonist, follistatin. Recombinant human Activin A is a 26.0 kDa disulfide-linked homodimer of two βA chains, each containing 116 amino acid residues.
VE:
1 * 10 µG
Artikel-Nr:
(PRSI90-470)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-470
Lokale Artikelnummer::
PRSI90-470
Beschreibung:
Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells and lymphokine activated killer cells. IL-2 also stimulates proliferation of antibody-producing B cells, activates neutrophils and induces mononuclear cells to secrete IFN-gamma and TNF-alpha and -beta. Moreover, studies have shown that IL-2 is required for activation-induced apoptosis, an important hemeostatic mechanism in the immune system, which is involved in the maintenance of peripheral tolerance to self-antigens.
VE:
1 * 10 µG
Artikel-Nr:
(PRSI76-814)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-814
Lokale Artikelnummer::
PRSI76-814
Beschreibung:
The FN50 monoclonal antibody specifically reacts with human CD69, the 27 to 33 kDa type II transmembrane protein also known as the very early activation antigen (VEA) or the activation inducer molecule (AIM). It is expressed as a disulfide-linked dimer on B cells, T cells, NK cells, platelets, eosinophils, and neutrophils. It increases in expression upon cell activation and seems to serve a role as a signaling receptor.
VE:
1 * 25 Tests
New Product
Artikel-Nr:
(PRSI6667)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6667
Lokale Artikelnummer::
PRSI6667
Beschreibung:
SPINK2 Antibody: Human serine proteinase inhibitor Kazal-type 2 (SPINK2) is required for maintaining normal spermatogenesis and potentially regulates serine protease-mediated apoptosis in male germ cells. It contains a typical kazal domain composed by six cysteine residues forming three disulfide bridges. SPINK2 functions as a trypsin/acrosin inhibitor and is synthesized mainly in the testis and seminal vesicle where its activity is engaged in fertility. SPINK2 plays a role in the pathogenesis of hereditary and chronic pancreatitis.
VE:
1 * 100 µG
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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