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2-(2-Fluorophenyl)-3-oxobutanenitrile
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2-(2-Fluorophenyl)-3-oxobutanenitrile
Artikel-Nr:
(APOSPC3756X-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC3756X-1G
Lokale Artikelnummer::
APOSPC3756X-1G
Beschreibung:
6-Fluoro-4-hydroxy-2-(trifluoromethyl)quinoline 97%
VE:
1 * 1 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
5-Nitro-2-(1H-pyrrol-1-yl)pyridine 95%
Artikel-Nr:
(APOSPC11172-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC11172-1G
Lokale Artikelnummer::
APOSPC11172-1G
Beschreibung:
4'-(Trifluormethyl)-4-biphenylcarbaldehyd
VE:
1 * 1 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2,4-Difluoro-3-(trifluoromethoxy)phenylacetylene 95%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
4-Bromo-2,3,6-trifluorobenzyl alcohol 95%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
5-(Difluoromethoxy)picolinic acid 99%
Artikel-Nr:
(APOSOR302080-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR302080-1G
Lokale Artikelnummer::
APOSOR302080-1G
Beschreibung:
1-(4-Methoxybenzyl)-4-bromo-5-nitro-1H-pyrazole
VE:
1 * 1 g
Artikel-Nr:
(BLDPBD328705-1G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD328705-1G
Lokale Artikelnummer::
BLDPBD328705-1G
Beschreibung:
1,5-Dichloro-2-iodo-3-methoxybenzene 95%
VE:
1 * 1 g
Artikel-Nr:
(H50204.03)
Lieferant:
Alfa Aesar
Hersteller-Artikelnummer::
H50204.03
Lokale Artikelnummer::
ALFAH50204.03
Beschreibung:
3-(4-Chlorphenyl)propionsäure ≥94%
VE:
1 * 1 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
5-Chlor-4-fluor-2-nitroanilin 97+%
Artikel-Nr:
(BLDPBD18229-100G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD18229-100G
Lokale Artikelnummer::
BLDPBD18229-100G
Beschreibung:
Methyl-4-brom-2-methoxybenzoat 98%
VE:
1 * 100 g
Artikel-Nr:
(BLDPBD139801-250MG)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD139801-250MG
Lokale Artikelnummer::
BLDPBD139801-250MG
Beschreibung:
Methyl-3-(4-pyridyl)acrylate 95%
VE:
1 * 250 mg
Artikel-Nr:
(BOSSBS-3494R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3494R-FITC
Lokale Artikelnummer::
BOSSBS-3494R-FITC
Beschreibung:
Serine/threonine protein kinase which is a central regulator of cellular metabolism, growth and survival in response to hormones, growth factors, nutrients, energy and stress signals. MTOR directly or indirectly regulates the phosphorylation of at least 800 proteins. Functions as part of 2 structurally and functionally distinct signaling complexes mTORC1 and mTORC2 (mTOR complex 1 and 2). Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. This includes phosphorylation of EIF4EBP1 and release of its inhibition toward the elongation initiation factor 4E (eiF4E). Moreover, phosphorylates and activates RPS6KB1 and RPS6KB2 that promote protein synthesis by modulating the activity of their downstream targets including ribosomal protein S6, eukaryotic translation initiation factor EIF4B, and the inhibitor of translation initiation PDCD4. Stimulates the pyrimidine biosynthesis pathway, both by acute regulation through RPS6KB1-mediated phosphorylation of the biosynthetic enzyme CAD, and delayed regulation, through transcriptional enhancement of the pentose phosphate pathway which produces 5-phosphoribosyl-1-pyrophosphate (PRPP), an allosteric activator of CAD at a later step in synthesis, this function is dependent on the mTORC1 complex. Regulates ribosome synthesis by activating RNA polymerase III-dependent transcription through phosphorylation and inhibition of MAF1 an RNA polymerase III-repressor. In parallel to protein synthesis, also regulates lipid synthesis through SREBF1/SREBP1 and LPIN1. To maintain energy homeostasis mTORC1 may also regulate mitochondrial biogenesis through regulation of PPARGC1A. mTORC1 also negatively regulates autophagy through phosphorylation of ULK1. Under nutrient sufficiency, phosphorylates ULK1 at 'Ser-758', disrupting the interaction with AMPK and preventing activation of ULK1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3494R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3494R-A750
Lokale Artikelnummer::
BOSSBS-3494R-A750
Beschreibung:
Serine/threonine protein kinase which is a central regulator of cellular metabolism, growth and survival in response to hormones, growth factors, nutrients, energy and stress signals. MTOR directly or indirectly regulates the phosphorylation of at least 800 proteins. Functions as part of 2 structurally and functionally distinct signaling complexes mTORC1 and mTORC2 (mTOR complex 1 and 2). Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. This includes phosphorylation of EIF4EBP1 and release of its inhibition toward the elongation initiation factor 4E (eiF4E). Moreover, phosphorylates and activates RPS6KB1 and RPS6KB2 that promote protein synthesis by modulating the activity of their downstream targets including ribosomal protein S6, eukaryotic translation initiation factor EIF4B, and the inhibitor of translation initiation PDCD4. Stimulates the pyrimidine biosynthesis pathway, both by acute regulation through RPS6KB1-mediated phosphorylation of the biosynthetic enzyme CAD, and delayed regulation, through transcriptional enhancement of the pentose phosphate pathway which produces 5-phosphoribosyl-1-pyrophosphate (PRPP), an allosteric activator of CAD at a later step in synthesis, this function is dependent on the mTORC1 complex. Regulates ribosome synthesis by activating RNA polymerase III-dependent transcription through phosphorylation and inhibition of MAF1 an RNA polymerase III-repressor. In parallel to protein synthesis, also regulates lipid synthesis through SREBF1/SREBP1 and LPIN1. To maintain energy homeostasis mTORC1 may also regulate mitochondrial biogenesis through regulation of PPARGC1A. mTORC1 also negatively regulates autophagy through phosphorylation of ULK1. Under nutrient sufficiency, phosphorylates ULK1 at 'Ser-758', disrupting the interaction with AMPK and preventing activation of ULK1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3495R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3495R-CY5
Lokale Artikelnummer::
BOSSBS-3495R-CY5
Beschreibung:
Serine/threonine protein kinase which is a central regulator of cellular metabolism, growth and survival in response to hormones, growth factors, nutrients, energy and stress signals. MTOR directly or indirectly regulates the phosphorylation of at least 800 proteins. Functions as part of 2 structurally and functionally distinct signaling complexes mTORC1 and mTORC2 (mTOR complex 1 and 2). Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. This includes phosphorylation of EIF4EBP1 and release of its inhibition toward the elongation initiation factor 4E (eiF4E). Moreover, phosphorylates and activates RPS6KB1 and RPS6KB2 that promote protein synthesis by modulating the activity of their downstream targets including ribosomal protein S6, eukaryotic translation initiation factor EIF4B, and the inhibitor of translation initiation PDCD4. Stimulates the pyrimidine biosynthesis pathway, both by acute regulation through RPS6KB1-mediated phosphorylation of the biosynthetic enzyme CAD, and delayed regulation, through transcriptional enhancement of the pentose phosphate pathway which produces 5-phosphoribosyl-1-pyrophosphate (PRPP), an allosteric activator of CAD at a later step in synthesis, this function is dependent on the mTORC1 complex. Regulates ribosome synthesis by activating RNA polymerase III-dependent transcription through phosphorylation and inhibition of MAF1 an RNA polymerase III-repressor. In parallel to protein synthesis, also regulates lipid synthesis through SREBF1/SREBP1 and LPIN1. To maintain energy homeostasis mTORC1 may also regulate mitochondrial biogenesis through regulation of PPARGC1A. mTORC1 also negatively regulates autophagy through phosphorylation of ULK1. Under nutrient sufficiency, phosphorylates ULK1 at 'Ser-758', disrupting the interaction with AMPK and preventing activation of ULK1. Also prevents autophagy through phosphorylation of the autophagy inhibitor DAP.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3494R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3494R-A555
Lokale Artikelnummer::
BOSSBS-3494R-A555
Beschreibung:
Serine/threonine protein kinase which is a central regulator of cellular metabolism, growth and survival in response to hormones, growth factors, nutrients, energy and stress signals. MTOR directly or indirectly regulates the phosphorylation of at least 800 proteins. Functions as part of 2 structurally and functionally distinct signaling complexes mTORC1 and mTORC2 (mTOR complex 1 and 2). Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. This includes phosphorylation of EIF4EBP1 and release of its inhibition toward the elongation initiation factor 4E (eiF4E). Moreover, phosphorylates and activates RPS6KB1 and RPS6KB2 that promote protein synthesis by modulating the activity of their downstream targets including ribosomal protein S6, eukaryotic translation initiation factor EIF4B, and the inhibitor of translation initiation PDCD4. Stimulates the pyrimidine biosynthesis pathway, both by acute regulation through RPS6KB1-mediated phosphorylation of the biosynthetic enzyme CAD, and delayed regulation, through transcriptional enhancement of the pentose phosphate pathway which produces 5-phosphoribosyl-1-pyrophosphate (PRPP), an allosteric activator of CAD at a later step in synthesis, this function is dependent on the mTORC1 complex. Regulates ribosome synthesis by activating RNA polymerase III-dependent transcription through phosphorylation and inhibition of MAF1 an RNA polymerase III-repressor. In parallel to protein synthesis, also regulates lipid synthesis through SREBF1/SREBP1 and LPIN1. To maintain energy homeostasis mTORC1 may also regulate mitochondrial biogenesis through regulation of PPARGC1A. mTORC1 also negatively regulates autophagy through phosphorylation of ULK1. Under nutrient sufficiency, phosphorylates ULK1 at 'Ser-758', disrupting the interaction with AMPK and preventing activation of ULK1.
VE:
1 * 100 µl
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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