[2-(3,4-Dimethylphenoxy)phenyl]methanol
Lieferant:
Alfa Aesar
Beschreibung:
ω-Brom-3,4-dichloracetophenon ≥98%
Artikel-Nr:
(BOSSBS-2127R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2127R-FITC
Lokale Artikelnummer::
BOSSBS-2127R-FITC
Beschreibung:
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2127R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2127R-A680
Lokale Artikelnummer::
BOSSBS-2127R-A680
Beschreibung:
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.
VE:
1 * 100 µl
Artikel-Nr:
(ACRO466852500)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
466852500
Lokale Artikelnummer::
ACRO466852500
Beschreibung:
Teniposide
VE:
1 * 250 mg
Artikel-Nr:
(BTIUBNUM0738-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM0738-50
Lokale Artikelnummer::
BTIUBNUM0738-50
Beschreibung:
Recognizes an oncofetal antigen of 220 kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This MAb defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.
VE:
1 * 50 µl
Lieferant:
Biotium
Beschreibung:
Recognizes an oncofetal antigen of 220 kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This MAb defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.
Artikel-Nr:
(BOSSBS-11177R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11177R-CY5
Lokale Artikelnummer::
BOSSBS-11177R-CY5
Beschreibung:
Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins which play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. CRISP-8 (Cysteine-rich secretory protein 8), also known as PI15 (Peptidase inhibitor 15), P25TI or SugarCrisp, is a 258 amino acid secreted protein that belongs to the CRISP family. Expressed at low levels in thyroid, prostate, salivary and mammary tissue, CRISP-8 functions as a serine protease inhibitor that exhibits weak inhibitory action against Trypsin, a serine protease found in the digestive system. In addition to its role as a protease inhibitor, CRISP-8 is secreted in neuroblastoma and glioblastoma cell lines, suggesting a role for CRISP-8 in tumor formation and metastasis within the central nervous system.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
Resazurin Natriumsalz, rein, hohe Reinheit biologische Färbemittel
Artikel-Nr:
(BOSSBS-3773R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3773R-CY7
Lokale Artikelnummer::
BOSSBS-3773R-CY7
Beschreibung:
Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3769R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3769R
Lokale Artikelnummer::
BOSSBS-3769R
Beschreibung:
Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9350R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9350R-A647
Lokale Artikelnummer::
BOSSBS-9350R-A647
Beschreibung:
Ubiquitin-dependent proteolysis mediates selective destruction of various cell cycle regulators, transcription factors and tumor suppressors. In eukaryotic cells, selective breakdown of cellular proteins is ensured by their ubiquitination and subsequent degradation by the 26S proteasome. At specific stages of development, embryo- and tissue-specific components of the 26S proteasome form, facilitating proteolysis. 20S Proteasome ?, also designated macropain subunit C2 or PROS-30, is a prosomal protein involved in a non-lysosomal ATP/ubiquitin-dependent proteolytic pathway. The entire proteasome is composed of at least 15 non-identical subunits which form a highly-ordered ring-shaped structure.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15126R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15126R-A680
Lokale Artikelnummer::
BOSSBS-15126R-A680
Beschreibung:
The smallest of the human chromosomes, 21 makes up about 1.5% of the human genome. Chromosome 21 contains nearly 300 genes and 47 million base pairs. Down syndrome, also known as trisomy 21, is the disease most commonly associated with chromosome 21. Alzheimer's disease, Jervell and Lange-Nielsen syndrome and amyotrophic lateral sclerosis are also associated with chromosome 21. Translocations are found to occur between chromosome 21 and 8, and chromosome 21 and 12, in certain leukemias. C21orf59, also known as C21orf48, is a 290 amino acid protein and its gene product has been provisionally designated C21orf59 pending further characterization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9350R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9350R-A680
Lokale Artikelnummer::
BOSSBS-9350R-A680
Beschreibung:
Ubiquitin-dependent proteolysis mediates selective destruction of various cell cycle regulators, transcription factors and tumor suppressors. In eukaryotic cells, selective breakdown of cellular proteins is ensured by their ubiquitination and subsequent degradation by the 26S proteasome. At specific stages of development, embryo- and tissue-specific components of the 26S proteasome form, facilitating proteolysis. 20S Proteasome ?, also designated macropain subunit C2 or PROS-30, is a prosomal protein involved in a non-lysosomal ATP/ubiquitin-dependent proteolytic pathway. The entire proteasome is composed of at least 15 non-identical subunits which form a highly-ordered ring-shaped structure.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0474R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0474R-A750
Lokale Artikelnummer::
BOSSBS-0474R-A750
Beschreibung:
Human IgA (immunoglobulin A) is a glycosylated protein of 160 kDa and is produced as a monomer or as a J chain linked dimer. Monomeric IgA constitutes 5-15 % of the serum immunoglobulins whereas dimeric IgA is localised to mucosa surfaces such as saliva, gastrointestinal secretion, bronchial fluids and milk. Mucosal IgA plays a major role in host defence by neutralising infectious agents at mucosal surfaces. The production is usually local and antigen specific IgA producing B cells can be found in regions under the lamina propria where they mature into dimeric IgA producing plasma cells. IgA deficiency is the most common immunodeficiency that may affect both serum and mucosal produced IgA.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0474R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0474R-HRP
Lokale Artikelnummer::
BOSSBS-0474R-HRP
Beschreibung:
Human IgA (immunoglobulin A) is a glycosylated protein of 160 kDa and is produced as a monomer or as a J chain linked dimer. Monomeric IgA constitutes 5-15 % of the serum immunoglobulins whereas dimeric IgA is localized to mucosa surfaces such as saliva, gastrointestinal secretion, bronchial fluids and milk. Mucosal IgA plays a major role in host defence by neutralising infectious agents at mucosal surfaces. The production is usually local and antigen specific IgA producing B cells can be found in regions under the lamina propria where they mature into dimeric IgA producing plasma cells. IgA deficiency is the most common immunodeficiency that may affect both serum and mucosal produced IgA.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11785R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11785R-HRP
Lokale Artikelnummer::
BOSSBS-11785R-HRP
Beschreibung:
Maspardin is a 308 amino acid cytoplasmic protein that is widely expressed. Belonging to the AB hydrolase superfamily, Maspardin colocalizes with CD4 on endosomal/trans-Golgi network. It is thought that Maspardin may act as a negative regulatory factor in CD4-dependent T-cell activation. Defects in the gene encoding Maspardin are the result of hereditary spastic paraplegia autosomal recessive type 21 (also designated Mast syndrome), an autosomal recessive neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. The gene encoding Maspardin is encoded by human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome.
VE:
1 * 100 µl
Preis auf Anfrage
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