Artikel-Nr:
(BOSSBS-8515R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8515R-CY3
Lokale Artikelnummer::
BOSSBS-8515R-CY3
Beschreibung:
Eukaryotic RNA polymerase II mediates the synthesis of mature and functional messenger RNA. This is a multistep process, called the transcription cycle, that includes five stages: preinitiation, promoter, clearance, elongation and termination. Elongation is thought to be a critical stage for the regulation of gene expression. ELL (11-19 lysine-rich leukemia protein), also designated MEN, functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II. It is also thought to regulate cellular proliferation. ELL is abundantly expressed in peripheral blood leukocytes, skeletal muscle, placenta and testis, with lower expression in spleen, thymus, heart, brain, lung, kidney, liver and ovary. The gene encoding human ELL, which maps to chromosome 19p13.1, is one of several genes that undergo translocation with the MLL gene on chromosome 11q23 in acute myeloid leukemia. MLL (myeloid/lymphoid leukemia, also designated ALL-1 and HRX) regulates embryonal and hematopoietic development.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8515R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8515R-CY7
Lokale Artikelnummer::
BOSSBS-8515R-CY7
Beschreibung:
Eukaryotic RNA polymerase II mediates the synthesis of mature and functional messenger RNA. This is a multistep process, called the transcription cycle, that includes five stages: preinitiation, promoter, clearance, elongation and termination. Elongation is thought to be a critical stage for the regulation of gene expression. ELL (11-19 lysine-rich leukemia protein), also designated MEN, functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II. It is also thought to regulate cellular proliferation. ELL is abundantly expressed in peripheral blood leukocytes, skeletal muscle, placenta and testis, with lower expression in spleen, thymus, heart, brain, lung, kidney, liver and ovary. The gene encoding human ELL, which maps to chromosome 19p13.1, is one of several genes that undergo translocation with the MLL gene on chromosome 11q23 in acute myeloid leukemia. MLL (myeloid/lymphoid leukemia, also designated ALL-1 and HRX) regulates embryonal and hematopoietic development.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3509R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3509R-CY5.5
Lokale Artikelnummer::
BOSSBS-3509R-CY5.5
Beschreibung:
Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells (By similarity). Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8515R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8515R-A555
Lokale Artikelnummer::
BOSSBS-8515R-A555
Beschreibung:
Eukaryotic RNA polymerase II mediates the synthesis of mature and functional messenger RNA. This is a multistep process, called the transcription cycle, that includes five stages: preinitiation, promoter, clearance, elongation and termination. Elongation is thought to be a critical stage for the regulation of gene expression. ELL (11-19 lysine-rich leukemia protein), also designated MEN, functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II. It is also thought to regulate cellular proliferation. ELL is abundantly expressed in peripheral blood leukocytes, skeletal muscle, placenta and testis, with lower expression in spleen, thymus, heart, brain, lung, kidney, liver and ovary. The gene encoding human ELL, which maps to chromosome 19p13.1, is one of several genes that undergo translocation with the MLL gene on chromosome 11q23 in acute myeloid leukemia. MLL (myeloid/lymphoid leukemia, also designated ALL-1 and HRX) regulates embryonal and hematopoietic development.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8515R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8515R-A488
Lokale Artikelnummer::
BOSSBS-8515R-A488
Beschreibung:
Eukaryotic RNA polymerase II mediates the synthesis of mature and functional messenger RNA. This is a multistep process, called the transcription cycle, that includes five stages: preinitiation, promoter, clearance, elongation and termination. Elongation is thought to be a critical stage for the regulation of gene expression. ELL (11-19 lysine-rich leukemia protein), also designated MEN, functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II. It is also thought to regulate cellular proliferation. ELL is abundantly expressed in peripheral blood leukocytes, skeletal muscle, placenta and testis, with lower expression in spleen, thymus, heart, brain, lung, kidney, liver and ovary. The gene encoding human ELL, which maps to chromosome 19p13.1, is one of several genes that undergo translocation with the MLL gene on chromosome 11q23 in acute myeloid leukemia. MLL (myeloid/lymphoid leukemia, also designated ALL-1 and HRX) regulates embryonal and hematopoietic development.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4817R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4817R-A488
Lokale Artikelnummer::
BOSSBS-4817R-A488
Beschreibung:
Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4817R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4817R-HRP
Lokale Artikelnummer::
BOSSBS-4817R-HRP
Beschreibung:
Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3509R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3509R-HRP
Lokale Artikelnummer::
BOSSBS-3509R-HRP
Beschreibung:
Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells (By similarity). Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8241R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8241R-A350
Lokale Artikelnummer::
BOSSBS-8241R-A350
Beschreibung:
Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation (By similarity). Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
An aminoglycoside antibiotic.
Artikel-Nr:
(516-8200)
Lieferant:
Pall Laboratory
Hersteller-Artikelnummer::
FS007X70
Lokale Artikelnummer::
PALLFS007X70
Beschreibung:
Ultralab™ systems, composed of Ultrareservoir™ containers and Ultrapump™ II pumps, are designed as a rapid, efficient replacement of dialysis for buffer exchange and desalting of macromolecules.
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-14082R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-14082R-A680
Lokale Artikelnummer::
BOSSBS-14082R-A680
Beschreibung:
Essential factor involved in transcription-coupled nucleotide excision repair which allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Upon DNA-binding, it locally modifies DNA conformation by wrapping the DNA around itself, thereby modifying the interface between stalled RNA polymerase II and DNA. It is required for transcription-coupled repair complex formation. It recruits the CSA complex (DCX(ERCC8) complex), nucleotide excision repair proteins and EP300 to the at sites of RNA polymerase II-blocking lesions.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6947R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6947R-CY5.5
Lokale Artikelnummer::
BOSSBS-6947R-CY5.5
Beschreibung:
KRT82 is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this keratin appears to be a hair cuticle-specific keratin.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
EDTA (Ethylendiamintetraessigsäure) 99%, rein
Artikel-Nr:
(BOSSBS-3971R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3971R-CY7
Lokale Artikelnummer::
BOSSBS-3971R-CY7
Beschreibung:
Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8377R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8377R-A750
Lokale Artikelnummer::
BOSSBS-8377R-A750
Beschreibung:
NFX1 is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. It may play a role in the inflammatory response, regulating its duration by limiting the period in which class II MHC molecules are induced by IFN gamma. The RING type zinc finger domain interacts with an ubiquitin conjugating enzyme (E2) and facilitates ubiquitination.
VE:
1 * 100 µl
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