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Cobalt(II)hydroxid
Artikel-Nr:
(BOSSBS-8241R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8241R
Lokale Artikelnummer::
BOSSBS-8241R
Beschreibung:
Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation (By similarity). Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7723R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7723R-A680
Lokale Artikelnummer::
BOSSBS-7723R-A680
Beschreibung:
Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1597R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1597R-A647
Lokale Artikelnummer::
BOSSBS-1597R-A647
Beschreibung:
The HRPT2 gene product, parafibromin, is a tumor suppressor protein that is part of the human Paf1 complex. The yeast counterpart to this complex is part of the RNA polymerase II complex as well, and is important for histone modification and connections to posttranscriptional events. Human parafibromin also associates with the RNA polymerase II large subunit.
VE:
1 * 100 µl
Artikel-Nr:
(ABCAAB196152-100)
Lieferant:
Abcam
Hersteller-Artikelnummer::
AB196152-100
Lokale Artikelnummer::
ABCAAB196152-100
Beschreibung:
Anti-RNA polymerase II CTD repeat YSPTSPS (phospho S5) Rabbit Monoclonal Antibody [clone: EP1510Y] (Alexa Fluor® 488)
VE:
1 * 100 µl
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BOSSBS-7891R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7891R-A750
Lokale Artikelnummer::
BOSSBS-7891R-A750
Beschreibung:
Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex, also called positive transcription elongation factor B (P-TEFB), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNAP II).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7891R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7891R-CY5
Lokale Artikelnummer::
BOSSBS-7891R-CY5
Beschreibung:
Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex, also called positive transcription elongation factor B (P-TEFB), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNAP II).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7891R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7891R-A350
Lokale Artikelnummer::
BOSSBS-7891R-A350
Beschreibung:
Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex, also called positive transcription elongation factor B (P-TEFB), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNAP II).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7891R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7891R-CY3
Lokale Artikelnummer::
BOSSBS-7891R-CY3
Beschreibung:
Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex, also called positive transcription elongation factor B (P-TEFB), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNAP II).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4237R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4237R-CY3
Lokale Artikelnummer::
BOSSBS-4237R-CY3
Beschreibung:
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP-7, BMP-2 and, less efficiently, BMP-4. Binding is weak but enhanced by the presence of type I receptors for BMPs.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DR and DP. Human MHC class II antigens are transmembrane glycoproteins composed of an chain (36 kDa) and a chain (27 kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six and ten chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.
Artikel-Nr:
(1.51419.0001)
Lieferant:
Merck
Hersteller-Artikelnummer::
1.51419.0001
Lokale Artikelnummer::
MERC1.51419.0001
Beschreibung:
Merck Säulen sind in 3 Ausführungen erhältlich.
VE:
1 * 1 ST
Artikel-Nr:
(ABCAAB311644-100UL)
Lieferant:
Abcam
Beschreibung:
Anti-RNA polymerase II CTD repeat YSPTSPS (phospho S2) Rabbit Monoclonal Antibody [clone: EPR18855] (Alexa Fluor® 594)
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11988R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11988R-A488
Lokale Artikelnummer::
BOSSBS-11988R-A488
Beschreibung:
Brain-specific neurabin I (neural tissue-specific F-actin binding protein I) is highly concentrated in the synapse of developed neurons; it localizes in the growth cone lamellipodia during neuronal development (1). Suppression of endogenous neurabin in rat hippocampal neurons inhibits neurite formation (1). Neurabin I recruits active PP1 via a PP1-docking sequence; mutation of the PP1-binding motif halts filopodia and restores stress fibers in neurabin I-expressing cells (2,3). Neurabin II (Spinophilin) is ubiquitously expressed but is abundantly expressed in brain (4). Neurabin II localizes to neuronal dentritic spines, which are the specialized protrusions from dendritic shafts that receive most of the excitatory input in the CNS (5). Neurabin II may regulate dendritic spine properties as neurabin II(-) mice have increased spine density during development in vitro and exhibit altered filopodial formation in cultured cells (5). Neurabin may also play a role in glutamatergic transmission as Neurabin II(-) mice exhibit reduced long-term depression and resistance to kainate-induced seizures and neronal apoptosis (5). Neurabin II complexes with the catalytic subunit of protein phosphatase-1 (PP1) in vitro thus modulating the activity of PP1 (4).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12261R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12261R-CY7
Lokale Artikelnummer::
BOSSBS-12261R-CY7
Beschreibung:
RTF1 is the the major histocompatibility complex (MHC) in the rat which contains genes that code for two class II histocompatibility antigens. RT1-B is an antigen of the RT1 complex. It is a protein dimer consisting of an alpha and beta glycoprotein chain and is homologous to I-A and I-E genes, respectively, in the H-2 complex of the mouse. MHC Class II antigens are useful in studying T helper cell interaction with class II positive antigen presenting cells (dendritic cells, B cells, macrophages) and offer new possibilities for studying the development of T helper cells since these also stain stromal cells in the thymus.
VE:
1 * 100 µl
Lieferant:
Sartorius Balances
Beschreibung:
Halbmikrowaagen haben eine Ablesbarkeit von 0,01 mg oder 10 µg und einen maximalen Wägebereich von bis zu 220 g.
Artikel-Nr:
(BOSSBS-4298R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4298R-A350
Lokale Artikelnummer::
BOSSBS-4298R-A350
Beschreibung:
Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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