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Cobalt(II)hydroxid
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Cobalt(II)hydroxid
Artikel-Nr:
(HPLCNINKIT.)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRCNINKIT
Beschreibung:
Ninhydrin-Reagenz-Kit (for buffer PF)
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-0644R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0644R-A350
Lokale Artikelnummer::
BOSSBS-0644R-A350
Beschreibung:
The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17. [provided by RefSeq, Aug 2010]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12122R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12122R-A680
Lokale Artikelnummer::
BOSSBS-12122R-A680
Beschreibung:
Voltage-gated sodium channels are selective ion channels that regulate the permeability of sodium ions in excitable cells. During the propagation of an action potential, sodium channels allow an influx of sodium ions, which rapidly depolarizes the cell. Na+ CP type II beta(sodium channel, voltage-gated, type II, beta), also known as SCN2B, is a 215 amino acid single-pass type I membrane protein that plays a critical role in the expression and assembly of the heterotrimeric complex of the sodium channel and interacts with Tenascin-R to influence the clustering and regulation of sodium channels at nodes of Ranvier. Expressed specifically in brain, Na+ CP type II beta contains one Ig-like C2-type (immunoglobulin-like) domain and is encoded by a gene that maps to human chromosome 11q23.3 and mouse chromosome 9 A5.2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2924R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2924R-A750
Lokale Artikelnummer::
BOSSBS-2924R-A750
Beschreibung:
May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2924R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2924R-A680
Lokale Artikelnummer::
BOSSBS-2924R-A680
Beschreibung:
May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9971R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9971R-A750
Lokale Artikelnummer::
BOSSBS-9971R-A750
Beschreibung:
Interacts with phosphorylated C-terminal heptapeptiderepeat domain (CTD) of the largest RNA polymerase II subunitPOLR2A, and participates in dephosphorylation of the CTD. Transcriptional regulator which enhances expression of CCND1.Promotes binding of RNA polymerase II to the CCDN1 promoter and tothe termination region before the poly-A site but decreases itsbinding after the poly-A site. Prevents RNA polymerase II from reading through the 3' end termination site and may allow it to be recruited back to the promoter through promotion of the formation of a chromatin loop. Also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A. Promotes cell proliferation.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Recognizes a 77-85 kDa protein, identified as cellular or tissue transglutaminase II (TGase II). Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. The identification of transglutaminase as the main antigen of endomysium antibodies allows a new diagnostic approach to celiac disease (CD), a genetic, immunologically mediated small bowel enteropathy that causes malabsorption. TGase II is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound healing.
Artikel-Nr:
(BOSSBS-4237R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4237R-CY5.5
Lokale Artikelnummer::
BOSSBS-4237R-CY5.5
Beschreibung:
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP-7, BMP-2 and, less efficiently, BMP-4. Binding is weak but enhanced by the presence of type I receptors for BMPs.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Bariumnitrat 99.999%
Artikel-Nr:
(BOSSBS-0766R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0766R-HRP
Lokale Artikelnummer::
BOSSBS-0766R-HRP
Beschreibung:
Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8241R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8241R-HRP
Lokale Artikelnummer::
BOSSBS-8241R-HRP
Beschreibung:
Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation (By similarity). Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8241R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8241R-A488
Lokale Artikelnummer::
BOSSBS-8241R-A488
Beschreibung:
Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation (By similarity). Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1913R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1913R-A750
Lokale Artikelnummer::
BOSSBS-1913R-A750
Beschreibung:
Matrix Metalloproteinase 8 (MMP8) is also known as neutrophil collagenase and collagenase 2. MMP8 degrades fibrillar collagens types I, II, III, aggrecan, serpins and alpha 2 macroglobulin. All collagenases cleave fibrillar collagens at one specific site resulting in generation of N terminal three quarter and C terminal one quarter fragments, which then denature to gelatin at body temperature. The substrate specificity of collagenases is variable: MMP1 degrades type III collagen more efficiently than type I or type II collagen, whereas MMP8 is more potent in degrading type I collagen than type III or type II collagen. MMP13, in turn degrades type II collagen 6 fold more efficiently than type I and type II collagens and displays almost 50 fold stronger gelatinolytic activity than MMP1 and MMP8. MMP8 is very similar to MMP1, sharing 57 % amino acid identity. Most cell types do not produce MMP8. Until recently, it was thought that MMP8 was produced exclusively by neutrophils, but it has also been detected in other cell types including arthritic chondrocytes and gingival fibroblasts. The human MMP8 gene has the chromosomal location of 11q22.2-22.3. MMP8 is heavily glycosylated, and the zymogen has a mass of 85 Kd. The zymogen is quickly activated to the 64 Kd form, and this breaks down to a cascade of active forms.
VE:
1 * 100 µl
Artikel-Nr:
(ABCAAB313129-100UL)
Lieferant:
Abcam
Beschreibung:
Anti-RNA polymerase II CTD repeat YSPTSPS (phospho S2) Rabbit Monoclonal Antibody [clone: EPR18855] (Alexa Fluor® 555)
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
Bariumnitrat ≥99%
Artikel-Nr:
(ABCAAB252855-100)
Lieferant:
Abcam
Hersteller-Artikelnummer::
AB252855-100
Lokale Artikelnummer::
ABCAAB252855-100
Beschreibung:
Anti-RNA polymerase II CTD repeat YSPTSPS (phospho S2) Rat Monoclonal Antibody [clone: 30000000000]
VE:
1 * 100 µG
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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