Copper(II)+gluconate
Artikel-Nr:
(BOSSBS-5098R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5098R-CY5
Lokale Artikelnummer::
BOSSBS-5098R-CY5
Beschreibung:
Binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5968R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5968R-CY5.5
Lokale Artikelnummer::
BOSSBS-5968R-CY5.5
Beschreibung:
Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7896R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7896R-A647
Lokale Artikelnummer::
BOSSBS-7896R-A647
Beschreibung:
Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8175R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8175R-CY5
Lokale Artikelnummer::
BOSSBS-8175R-CY5
Beschreibung:
Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8175R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8175R-CY7
Lokale Artikelnummer::
BOSSBS-8175R-CY7
Beschreibung:
Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8530R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8530R-CY3
Lokale Artikelnummer::
BOSSBS-8530R-CY3
Beschreibung:
Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8175R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8175R-CY5.5
Lokale Artikelnummer::
BOSSBS-8175R-CY5.5
Beschreibung:
Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8530R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8530R
Lokale Artikelnummer::
BOSSBS-8530R
Beschreibung:
Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8530R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8530R-CY5
Lokale Artikelnummer::
BOSSBS-8530R-CY5
Beschreibung:
Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0709R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0709R-A647
Lokale Artikelnummer::
BOSSBS-0709R-A647
Beschreibung:
Type II collagen is specific for cartilaginous tissues. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0709R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0709R-FITC
Lokale Artikelnummer::
BOSSBS-0709R-FITC
Beschreibung:
Type II collagen is specific for cartilaginous tissues. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11766R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11766R-CY7
Lokale Artikelnummer::
BOSSBS-11766R-CY7
Beschreibung:
In eukaryotic systems, initiation of transcription from protein-coding genes is a complex process requiring RNA polymerase II and broad families of auxiliary transcription factors. Such factors can be divided into two major functional classes: the basal factors that are required for transcription of all Pol II genes, including TFIIA, TFIIB, TFIID, TFIIE, TFIIF and TFIIH; and sequence-specific factors that regulate gene expression. The basal transcription factors and Pol II form a specific multiprotein complex near the transcription start site by interacting with core promotor elements such as the TATA box generally located 25-30 base pairs upstream of the transcription start site. Binding of TFIID to the TATA element initiates assembly of the other factors into a pre-initiation complex. The TATA-binding subunit of TFIID (designated TFIIDt or TBP) from higher eukaryotes contains a highly conserved 180 amino acid C-terminal domain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7879R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7879R
Lokale Artikelnummer::
BOSSBS-7879R
Beschreibung:
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. The FACT complex is probably also involved in phosphorylation of 'Ser-392' of p53/TP53 via its association with CK2 (casein kinase II). Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0644R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0644R-A555
Lokale Artikelnummer::
BOSSBS-0644R-A555
Beschreibung:
The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17. [provided by RefSeq, Aug 2010]
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Recognizes a 77-85 kDa protein, identified as cellular or tissue transglutaminase II (TGase II). Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. The identification of transglutaminase as the main antigen of endomysium antibodies allows a new diagnostic approach to celiac disease (CD), a genetic, immunologically mediated small bowel enteropathy that causes malabsorption. TGase II is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound healing.
Artikel-Nr:
(BOSSBS-7123R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7123R
Lokale Artikelnummer::
BOSSBS-7123R
Beschreibung:
Forms a high-affinity link between the actin cytoskeleton and the membrane. Isoform 1 (archvillin) is among the first costameric proteins to assemble during myogenesis and it contributes to myogenic membrane structure and differentiation. Appears to be involved in myosin II assembly. May modulate myosin II regulation through MLCK during cell spreading, an initial step in cell migration. May play a role in invadopodial function. Isoform 2 may be involved in modulation of focal adhesions. Supervillin-mediated down-regulation of focal adhesions involves binding to TRIP6. Plays a role in cytokinesis through KIF14 interaction (By similarity).
VE:
1 * 100 µl
Preis auf Anfrage
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