β-tri-Calciumphosphat+(β-Phase)
Artikel-Nr:
(BOSSBS-6417R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6417R-CY7
Lokale Artikelnummer::
BOSSBS-6417R-CY7
Beschreibung:
Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol 4-phosphate) and PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Involved in the activation of AKT1 upon stimulation by G-protein coupled receptors (GPCRs) ligands such as CXCL12, sphingosine 1-phosphate, and lysophosphatidic acid. May also act downstream receptor tyrosine kinases. Required in different signaling pathways for stable platelet adhesion and aggregation. Plays a role in platelet activation signaling triggered by GPCRs, alpha-IIb/beta-3 integrins (ITGA2B/ ITGB3) and ITAM (immunoreceptor tyrosine-based activation motif)-bearing receptors such as GP6. Regulates the strength of adhesion of ITGA2B/ ITGB3 activated receptors necessary for the cellular transmission of contractile forces. Required for platelet aggregation induced by F2 (thrombin) and thromboxane A2 (TXA2). Has a role in cell survival. May have a role in cell migration. Involved in the early stage of autophagosome formation. Modulates the intracellular level of PtdIns3P (Phosphatidylinositol 3-phosphate) and activates PIK3C3 kinase activity. May act as a scaffold, independently of its lipid kinase activity to positively regulate autophagy. May have a role in insulin signaling as scaffolding protein in which the lipid kinase activity is not required. May have a kinase-independent function in regulating cell proliferation and in clathrin-mediated endocytosis. Mediator of oncogenic signal in cell lines lacking PTEN. The lipid kinase activity is necessary for its role in oncogenic transformation. Required for the growth of ERBB2 and RAS driven tumors.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11457R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11457R-A750
Lokale Artikelnummer::
BOSSBS-11457R-A750
Beschreibung:
Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
(±)-tert-Butyl-2-brombutyrat 98%
Artikel-Nr:
(APOSPC7976-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC7976-1G
Lokale Artikelnummer::
APOSPC7976-1G
Beschreibung:
2-Brom-N-butyl-5-fluorbenzamid
VE:
1 * 1 g
Artikel-Nr:
(BOSSBS-3616R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3616R-HRP
Lokale Artikelnummer::
BOSSBS-3616R-HRP
Beschreibung:
NCF4 is a cytosolic oxidase associated protein. It is a component of the nicotinamide adenine dinucleotide phosphate oxidase, which mediates down regulation of NADPH oxidase through interactions with its SH3 domain. NCF4 is associated with p67 phox but is absent in patients with chronic granulomatous disease who lack p67 phox.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3616R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3616R-A647
Lokale Artikelnummer::
BOSSBS-3616R-A647
Beschreibung:
NCF4 is a cytosolic oxidase associated protein. It is a component of the nicotinamide adenine dinucleotide phosphate oxidase, which mediates down regulation of NADPH oxidase through interactions with its SH3 domain. NCF4 is associated with p67 phox but is absent in patients with chronic granulomatous disease who lack p67 phox.
VE:
1 * 100 µl
Artikel-Nr:
(APOSOR110337-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR110337-1G
Lokale Artikelnummer::
APOSOR110337-1G
Beschreibung:
2-Butyl-1,3-benzothiazole
VE:
1 * 1 g
Artikel-Nr:
(BOSSBS-11457R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11457R-A555
Lokale Artikelnummer::
BOSSBS-11457R-A555
Beschreibung:
Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.
VE:
1 * 100 µl
Artikel-Nr:
(USBI029208)
Lieferant:
US Biological
Hersteller-Artikelnummer::
029208
Lokale Artikelnummer::
USBI029208
Beschreibung:
Anti-M6PR Rabbit Polyclonal Antibody (Biotin)
VE:
1 * 50 µG
Artikel-Nr:
(APOSOR471032-5G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR471032-5G
Lokale Artikelnummer::
APOSOR471032-5G
Beschreibung:
tert-Butyl iodoacetate
VE:
1 * 5 g
Artikel-Nr:
(BOSSBS-7916R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7916R
Lokale Artikelnummer::
BOSSBS-7916R
Beschreibung:
Converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway: although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded. Also has ManNAc kinase activity.
VE:
1 * 100 µl
Artikel-Nr:
(SERA30002.01)
Lieferant:
Serva
Hersteller-Artikelnummer::
30002.01
Lokale Artikelnummer::
SERA30002.01
Beschreibung:
Naphthol AS-MX-phosphat
VE:
1 * 250 mg
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Lieferant:
Alfa Aesar
Beschreibung:
4-tert-Butyl-o-phenylendiamin 97%
Artikel-Nr:
(BOSSBS-9027R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9027R-CY5.5
Lokale Artikelnummer::
BOSSBS-9027R-CY5.5
Beschreibung:
This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. [provided by RefSeq, Mar 2011].
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
O-tert-Butyl-L-serine 98%
Preis auf Anfrage
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