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1-(3-Bromophenyl)-cyclobutanemethanamine
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1-(3-Bromophenyl)-cyclobutanemethanamine
Artikel-Nr:
(BOSSBS-6044R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6044R-A750
Lokale Artikelnummer::
BOSSBS-6044R-A750
Beschreibung:
Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation is required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9046R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9046R-A647
Lokale Artikelnummer::
BOSSBS-9046R-A647
Beschreibung:
The product of this gene belongs to the family of transient receptor potential (TRP) channels. TRP channels are cation-selective channels important for cellular calcium signaling and homeostasis. The protein encoded by this gene mediates calcium entry, and this entry is potentiated by calcium store depletion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1015R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1015R-A680
Lokale Artikelnummer::
BOSSBS-1015R-A680
Beschreibung:
Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6380R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6380R-A647
Lokale Artikelnummer::
BOSSBS-6380R-A647
Beschreibung:
ERCC6L belongs to the SNF2 ATPase family and acts as an essential component of the spindle assembly checkpoint. It contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. It acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase. ERCC6L may also play a role in the teratogenic action of alcohol.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6459R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6459R-A555
Lokale Artikelnummer::
BOSSBS-6459R-A555
Beschreibung:
Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7725R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7725R-A488
Lokale Artikelnummer::
BOSSBS-7725R-A488
Beschreibung:
Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9664R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9664R-A647
Lokale Artikelnummer::
BOSSBS-9664R-A647
Beschreibung:
DUX3 belongs to the paired homeobox family and contains 2 homeobox DNA-binding domains. It expressed in hepatoma Hep3B cells. DUX genes are present in 3.3-kilobase elements, a tandem repeat family scattered in the genome found on the short arms of all acrocentric chromosomes as well as on several other chromosomes. May be functional despite lack of introns and of a poly(A) addition signal. Two different isoforms are known.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6286R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6286R-A350
Lokale Artikelnummer::
BOSSBS-6286R-A350
Beschreibung:
TMPRSS4 is a member of the peptidase S1 family and contains 1 LDL receptor class A domain, 1 peptidase S1 domain and 1 SRCR domain. It is a probable membrane protease capable of activating ENaC and may process sodium channels in endothelial cells. TMPRSS4 is overexpressed in thyroid neoplasms, and splice variants in TMPRSS4 are thought to be linked with different cancers. Three named isoforms are produced by alternative splicing.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11204R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11204R-A555
Lokale Artikelnummer::
BOSSBS-11204R-A555
Beschreibung:
Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11381R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11381R-A488
Lokale Artikelnummer::
BOSSBS-11381R-A488
Beschreibung:
Contributes to degradation of proteins cross-linked by transglutaminases. Degrades the cross-link between a lysine and a glutamic acid residue from two proteins that have been cross-linked by transglutaminases. Catalyzes the formation of 5-oxoproline from L-gamma-glutamyl-L-epsilon-lysine. Inactive with L-gamma-glutamyl-alpha-amino acid substrates such as L-gamma-glutamyl-L-alpha-cysteine and L-gamma-glutamyl-L-alpha-alanine.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7885R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7885R-A555
Lokale Artikelnummer::
BOSSBS-7885R-A555
Beschreibung:
May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription.Tissue specificity: Ubiquitously expressed. Expression is down-regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6044R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6044R-A555
Lokale Artikelnummer::
BOSSBS-6044R-A555
Beschreibung:
Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation is required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6259R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6259R-A350
Lokale Artikelnummer::
BOSSBS-6259R-A350
Beschreibung:
Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments. Inhibits the SHH and WNT1 pathways, thereby enhancing adipogenesis. In addition, promotes expression of the gluconeogenic enzyme glucose-6-phosphatase (G6PC).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11127R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11127R-A555
Lokale Artikelnummer::
BOSSBS-11127R-A555
Beschreibung:
Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2554R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2554R-A350
Lokale Artikelnummer::
BOSSBS-2554R-A350
Beschreibung:
CXCL15 (Lungkine) is a CXC chemokine that is expressed in murine lung epithelial cells and, to a lesser extent, in certain fetal tissues. No human homolog has been identified and a specific cell surface receptor has not yet been found. Lungkine expression in lung tissue is elevated in response to inflammation, at which time it acts to specifically recruit neutrophils and direct them into the lung airway.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3638R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3638R-A350
Lokale Artikelnummer::
BOSSBS-3638R-A350
Beschreibung:
Plexin A2 is a coreceptor for SEMA3A and is necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. This coreceptor plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin in which the plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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