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5-Amino-7-azaindole
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5-Amino-7-azaindole
Artikel-Nr:
(PRSI29-651)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-651
Lokale Artikelnummer::
PRSI29-651
Beschreibung:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI31-007)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
31-007
Lokale Artikelnummer::
PRSI31-007
Beschreibung:
Histone H3, along with histone H4, plays a central role in nucleosome formation.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI91-206)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-206
Lokale Artikelnummer::
PRSI91-206
Beschreibung:
Glial Cell Line-Derived Neurotrophic Factor (GDNF) is a disulfide-linked homodimeric glycoprotein that belongs to the TGF- beta superfamily. It has been shown to promote the survival of various neuronal subpopulations in both the central as well as the peripheral nervous systems at different stages of their development. Human GDNF cDNA encodes a 211 amino acid residue prepropeptide that is processed to yield a dimeric protein. Mature human GDNF was predicted to contain two 134 amino acid residue subunits. Cells known to express GDNF include Sertoli cells, type 1 astrocytes, Schwann cells, neurons, pinealocytes and skeletal muscle cells. Mutations in this gene may be associated with Hirschsprung disease.
VE:
1 * 50 µG
Artikel-Nr:
(PRSIXW-7208)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
XW-7208
Lokale Artikelnummer::
PRSIXW-7208
Beschreibung:
Ras-GTPase-activating protein SH3-domain-binding protein; GAP binding protein; RasGAP-associated endoribonuclease G3BP. This protein is one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI30-342)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
30-342
Lokale Artikelnummer::
PRSI30-342
Beschreibung:
Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes.Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes (Yoshikawa et al., 1996).
VE:
1 * 100 µG
Artikel-Nr:
(PRSI45-142)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
45-142
Lokale Artikelnummer::
PRSI45-142
Beschreibung:
Anti-SERPINE1 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI42-328)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
42-328
Lokale Artikelnummer::
PRSI42-328
Beschreibung:
Anti-MUC5B Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI42-413)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
42-413
Lokale Artikelnummer::
PRSI42-413
Beschreibung:
Anti-GM2A Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI46-219)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
46-219
Lokale Artikelnummer::
PRSI46-219
Beschreibung:
Anti-TTR Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI28-877)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-877
Lokale Artikelnummer::
PRSI28-877
Beschreibung:
MLLT3 is a regulator of early erythroid and megakaryocytic cell fate in the human system. Expression of MLLT3 in human CD34+ cells induces acute myeloid, lymphoid, or mixed-lineage leukemia in immunodeficient mice. Translocation t (9;11) (p22;q23), a chromosomal aberration involving MLLT3 is associated with acute leukemias.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI27-358)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-358
Lokale Artikelnummer::
PRSI27-358
Beschreibung:
KLF1 is a transcription factor, originally identified in this laboratory, which plays a crucial role as a transcriptional activator at the adult beta-globin locus.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI30-710)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
30-710
Lokale Artikelnummer::
PRSI30-710
Beschreibung:
The structure of MAS1 indicates that it belongs to the class of receptors that are coupled to GTP-binding proteins and share a conserved structural motif, which is described as a '7-transmembrane segment' following the prediction that these hydrophobic segments form membrane-spanning alpha-helices. The MAS1 protein may be a receptor that, when activated, modulates a critical component in a growth-regulating pathway to bring about oncogenic effects.The structure of the MAS1 product indicates that it belongs to the class of receptors that are coupled to GTP-binding proteins and share a conserved structural motif, which is described as a '7-transmembrane segment' following the prediction that these hydrophobic segments form membrane-spanning alpha-helices. The MAS1 protein may be a receptor that, when activated, modulates a critical component in a growth-regulating pathway to bring about oncogenic effects.The structure of the MAS1 product indicates that it belongs to the class of receptors that are coupled to GTP-binding proteins and share a conserved structural motif, which is described as a '7-transmembrane segment' following the prediction that these hydrophobic segments form membrane-spanning alpha-helices. The MAS1 protein may be a receptor that, when activated, modulates a critical component in a growth-regulating pathway to bring about oncogenic effects.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI31-069)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
31-069
Lokale Artikelnummer::
PRSI31-069
Beschreibung:
Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. Regulator of G protein signaling 10 protein is localized in the nucleus. Two transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI28-692)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-692
Lokale Artikelnummer::
PRSI28-692
Beschreibung:
The function remains unknown.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI29-109)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-109
Lokale Artikelnummer::
PRSI29-109
Beschreibung:
PGBD1 belongs to the subfamily of piggyBac transposable element derived (PGBD) genes. The PGBD proteins appear to be novel, with no obvious relationship to other transposases, or other known protein families. This gene product is specifically expressed in the brain, however, its exact function is not known. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.The piggyBac family of proteins, found in diverse animals, are transposases related to the transposase of the canonical piggyBac transposon from the moth, Trichoplusia ni. This family also includes genes in several genomes, including human, that appear to have been derived from the piggyBac transposons. This gene belongs to the subfamily of piggyBac transposable element derived (PGBD) genes. The PGBD proteins appear to be novel, with no obvious relationship to other transposases, or other known protein families. This gene product is specifically expressed in the brain, however, its exact function is not known.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI50-270)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
50-270
Lokale Artikelnummer::
PRSI50-270
Beschreibung:
Tau is a key microtubule-associated protein that plays an important role in the formation of microtubules in axons (Binder et al. 1985). Six tau isoforms have been identified as products of a single gene produced by alternative mRNA splicing (Goedert 1990). Tau mutations have been implicated in many neurodegenerative disorders such as Alzheimer’s disease (AD), Pick’s disease and progressive supranuclear palsy. It has been well documented that hyperphosphorylated tau is a major component of paired helical filaments in AD brain (Lee 1995). Serine 416 has been demonstrated to be a major phosphorylation site in vitro by CaM kinase II (Steiner at al. 1990).
VE:
1 * 100 µl
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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