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Dimethyl+bicyclo[2.1.1]hexane-1,4-dicarboxylate
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Dimethyl+bicyclo[2.1.1]hexane-1,4-dicarboxylate
Artikel-Nr:
(201-2611)
Lieferant:
Lenz Laborglas GmbH & CO.KG
Hersteller-Artikelnummer::
05080001
Lokale Artikelnummer::
LENZ05080001
Beschreibung:
Duran® Borosilikatglas.
VE:
1 * 1 ST
Artikel-Nr:
(BIBB3766/03)
Lieferant:
SciLabware
Hersteller-Artikelnummer::
3766/03
Lokale Artikelnummer::
BIBB3766/03
Beschreibung:
PYREX® borosilicate glass.
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-7502R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7502R-HRP
Lokale Artikelnummer::
BOSSBS-7502R-HRP
Beschreibung:
REM (Rad and Gem related GTP binding protein) is a member of the Rad/Gem/Kir subfamily of Ras-like GTPases and shares with other members of this subfamily some unusual structural features. Among these are nonconservative amino acid substitutions within guanine nucleotide binding and hydrolysis domains, unique effector domains, extended N- and C-termini, and a conserved C-terminal sequence thought to mediate membrane association but lacking a classical isoprenylation motif. REM, with a predicted molecular weight of 32.9 kDa, is most highly expressed in cardiac muscle and is expressed at more moderate levels in lung, kidney and skeletal muscle. REM is phosphorylated in vivo and has been shown to interact with several 14-3-3 isoforms. It has been reported that the GTP-bound form of a related Ras-like GTPase, GEM/kir, inhibits high-voltage activated Ca2+ channel activities by interacting directly with the ?subunit. The reduced channel activities are the result of a decreased a-subunit expression at the plasma membrane. This inhibition of L-type Ca2+ channels prevents Ca2+-triggered exocytosis in hormone-secreting cells. There are data that suggest that REM similarly regulates Ca2+ channel expression.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9680R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9680R-A647
Lokale Artikelnummer::
BOSSBS-9680R-A647
Beschreibung:
C19orf28, also known as PP3501, is a multi-pass membrane protein that belongs to the major facilitator superfamily. The gene encoding C19orf28 localizes to chromosome 19 and, due to alternative splicing events, C19orf28 exists as two isoforms. Consisting of around 63 million bases with over 1,400 genes, chromosome 19 makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fc receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3. The C19orf28 gene product has been provisionally designated C19orf28 pending further characterization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3626R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3626R-CY5
Lokale Artikelnummer::
BOSSBS-3626R-CY5
Beschreibung:
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. There have been at least 12 different PKC isoforms identified in humans to date including alpha, beta I, beta II, gamma, delta, epsilon, zeta, eta, theta, iota, lambda, and mu. PKC gamma is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14).
VE:
1 * 100 µl
Lieferant:
EDQM
Beschreibung:
Organic Standard, Fluticasone impurity D, 6α,9-difluoro-11β-hydroxy-16α-methyl-17-[(methylsulfanyl)carbonyl]-3-oxoandrosta-1,4-dien-17α-ylpropanoate, Ph. Eur. standard
Artikel-Nr:
(EHERC13356200)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C13356200
Lokale Artikelnummer::
EHERC13356200
Beschreibung:
o-Ethyltoluol
VE:
1 * 250 mg
Artikel-Nr:
(BOSSBS-3423R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3423R
Lokale Artikelnummer::
BOSSBS-3423R
Beschreibung:
Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression. Recruitment of SETDB1 induces heterochromatinization. May play a role as a coactivator for CEBPB and NR3C1 in the transcriptional activation of ORM1. Also corepressor for ERBB4. Inhibits E2F1 activity by stimulating E2F1-HDAC1 complex formation and inhibiting E2F1 acetylation. May serve as a partial backup to prevent E2F1-mediated apoptosis in the absence of RB1. Important regulator of CDKN1A/p21(CIP1). Has E3 SUMO-protein ligase activity toward itself via its PHD-type zinc finger. Also specifically sumoylates IRF7, thereby inhibiting its transactivation activity. Ubiquitinates p53/TP53 leading to its proteosomal degradation; the function is enhanced by MAGEC2 and MAGEA2, and possibly MAGEA3 and MAGEA6. Mediates the nuclear localization of KOX1, ZNF268 and ZNF300 transcription factors.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3423R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3423R-CY5
Lokale Artikelnummer::
BOSSBS-3423R-CY5
Beschreibung:
Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression. Recruitment of SETDB1 induces heterochromatinization. May play a role as a coactivator for CEBPB and NR3C1 in the transcriptional activation of ORM1. Also corepressor for ERBB4. Inhibits E2F1 activity by stimulating E2F1-HDAC1 complex formation and inhibiting E2F1 acetylation. May serve as a partial backup to prevent E2F1-mediated apoptosis in the absence of RB1. Important regulator of CDKN1A/p21(CIP1). Has E3 SUMO-protein ligase activity toward itself via its PHD-type zinc finger. Also specifically sumoylates IRF7, thereby inhibiting its transactivation activity. Ubiquitinates p53/TP53 leading to its proteosomal degradation; the function is enhanced by MAGEC2 and MAGEA2, and possibly MAGEA3 and MAGEA6. Mediates the nuclear localization of KOX1, ZNF268 and ZNF300 transcription factors.
VE:
1 * 100 µl
Artikel-Nr:
(WITG0.850.101)
Lieferant:
WITEG LABORTECHNIK
Hersteller-Artikelnummer::
0.850.101
Lokale Artikelnummer::
WITG0.850.101
Beschreibung:
Borosilikatglas 3.3
VE:
1 * 1 ST
Lieferant:
DWK Life Sciences
Beschreibung:
Silicone, translucent.
Lieferant:
Alfa Aesar
Beschreibung:
Fasudilhydrochlorid ≥99%
Artikel-Nr:
(SIAL53262-5ML)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
53262-5ML
Lokale Artikelnummer::
SIAL53262-5ML
Beschreibung:
Hexylsilan, Sigma-Aldrich®
VE:
1 * 5 mL
Artikel-Nr:
(201-7414)
Lieferant:
HWS LABORTECHNIK
Hersteller-Artikelnummer::
1258500
Lokale Artikelnummer::
HWSA1258500
Beschreibung:
Chromnickel-Federstahldraht.
VE:
1 * 1 ST
Artikel-Nr:
(SEMA0221)
Lieferant:
SEMADENI
Hersteller-Artikelnummer::
0221
Lokale Artikelnummer::
SEMA0221
Beschreibung:
Funnels, made of PP, translucent, with slim stem.
VE:
1 * 1 ST
Lieferant:
BIONET RESEARCH
Beschreibung:
O-[(2,5-Dichlorophenyl)methyl]hydroxylamine hydrochloride
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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