Dimethyl+bicyclo[2.1.1]hexane-1,4-dicarboxylate
Artikel-Nr:
(BOSSBS-12259R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12259R-FITC
Lokale Artikelnummer::
BOSSBS-12259R-FITC
Beschreibung:
Glycosyltransferases that mediate the regio- and stereoselective transfer of sugars, such as the fucosyltransferases, determine cell surface-carbohydrate profiles, which are essential interfaces for biological recognition processes. Fucosyltransferases (FucTs) catalyze the covalent association of fucose to different positional linkages on sugar acceptor molecules. The carbohydrate moieties that are generated are covalently attached to cell surfaces and are necessary to ensure a surface contour that satisfies a variety of physiological roles. FucT-XI is a 492 amino acid single-pass type II membrane protein that belongs to the glycosyltransferase 10 family. Localizing to Golgi apparatus, FucT-XI may act as a fucosyltransferase and exists as two alternatively spliced isoforms. The gene encoding FucT-XI maps to mouse chromosome 14 A3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11217R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11217R-A750
Lokale Artikelnummer::
BOSSBS-11217R-A750
Beschreibung:
Myotubularin-related protein 14 (MTMR14), also known as Jumpy, is a myotubularin-related phosphoinositol-3-phosphate (PI3P) phosphatase. Mutations in the MTMR14 gene have been associated with centronuclear myopathy. MTMR14 deficiency in mice leads to altered calcium homeostasis and muscle disorders. MTMR14 has also been shown to play a role in autophagy, a process that is highly regulated by phosphatidylinositides through the type III PI3K, Vps34. MTMR14 was localised to autophagic isolation membranes and early autophagosomes. In these studies, MTMR14 inhibited autophagy and mutations of MTMR14 associated with centronuclear myopathy were also defective in autophagy inhibition. In zebrafish, MTMR14 knockdown was shown to increase the number of autophagosomes, suggesting that its activity is associated with an inhibition of autophagy.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0380R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0380R-A680
Lokale Artikelnummer::
BOSSBS-0380R-A680
Beschreibung:
Oligodendrocyte Marker. The classic group of Myelin basic protein (MBP) isoforms (isoforms 4 to 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilisation. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non classic group of MBP isoforms (isoforms 1 to 3/Golli MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T cells and neural cells. Differential splicing events combined to optional posttranslational modifications give a wide spectrum of isomers, each of them having maybe a specialized function.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11217R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11217R-A680
Lokale Artikelnummer::
BOSSBS-11217R-A680
Beschreibung:
Myotubularin-related protein 14 (MTMR14), also known as Jumpy, is a myotubularin-related phosphoinositol-3-phosphate (PI3P) phosphatase. Mutations in the MTMR14 gene have been associated with centronuclear myopathy. MTMR14 deficiency in mice leads to altered calcium homeostasis and muscle disorders. MTMR14 has also been shown to play a role in autophagy, a process that is highly regulated by phosphatidylinositides through the type III PI3K, Vps34. MTMR14 was localised to autophagic isolation membranes and early autophagosomes. In these studies, MTMR14 inhibited autophagy and mutations of MTMR14 associated with centronuclear myopathy were also defective in autophagy inhibition. In zebrafish, MTMR14 knockdown was shown to increase the number of autophagosomes, suggesting that its activity is associated with an inhibition of autophagy.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2423R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2423R-A680
Lokale Artikelnummer::
BOSSBS-2423R-A680
Beschreibung:
This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterised by muscle hypertrophy and decreased fat mass.
VE:
1 * 100 µl
Artikel-Nr:
(EHERC13955800)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C13955800
Lokale Artikelnummer::
EHERC13955800
Beschreibung:
Dimethylfumarat
VE:
1 * 0,25 g
Artikel-Nr:
(EHERCA14195500)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
CA14195500
Lokale Artikelnummer::
EHERCA14195500
Beschreibung:
n-Hexane 1 * 1 mL
VE:
1 * 1 mL
New Product
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 36 kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). About 40% of breast carcinomas are positive for Cyclin D1. Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
Artikel-Nr:
(BOSSBS-12259R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12259R-CY7
Lokale Artikelnummer::
BOSSBS-12259R-CY7
Beschreibung:
Glycosyltransferases that mediate the regio- and stereoselective transfer of sugars, such as the fucosyltransferases, determine cell surface-carbohydrate profiles, which are essential interfaces for biological recognition processes. Fucosyltransferases (FucTs) catalyze the covalent association of fucose to different positional linkages on sugar acceptor molecules. The carbohydrate moieties that are generated are covalently attached to cell surfaces and are necessary to ensure a surface contour that satisfies a variety of physiological roles. FucT-XI is a 492 amino acid single-pass type II membrane protein that belongs to the glycosyltransferase 10 family. Localizing to Golgi apparatus, FucT-XI may act as a fucosyltransferase and exists as two alternatively spliced isoforms. The gene encoding FucT-XI maps to mouse chromosome 14 A3.
VE:
1 * 100 µl
Artikel-Nr:
(BNUM0007-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM0007-50
Lokale Artikelnummer::
BTIUBNUM0007-50
Beschreibung:
Recognizes a protein of 36 kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). About 40% of breast carcinomas are positive for Cyclin D1. Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
VE:
1 * 50 µl
Artikel-Nr:
(ENAMEN300107419.1G)
Lieferant:
SIA ENAMINE
Hersteller-Artikelnummer::
EN300107419.1G
Lokale Artikelnummer::
ENAMEN300107419.1G
Beschreibung:
HEXAN-3-OL 1 * 1 g
VE:
1 * 1 g
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Artikel-Nr:
(CAYM29659-10)
Lieferant:
Cayman Chemical
Hersteller-Artikelnummer::
29659-10
Lokale Artikelnummer::
CAYM29659-10
Beschreibung:
LP-211 1 * 10 mg
VE:
1 * 10 mg
Artikel-Nr:
(EHERC14727500)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C14727500
Lokale Artikelnummer::
EHERC14727500
Beschreibung:
Dimethylmaleat
VE:
1 * 0,25 g
Lieferant:
Thermo Scientific
Beschreibung:
D(+)-Fenchon 97%
Artikel-Nr:
(MAYBKM04101.250)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
KM04101.250
Lokale Artikelnummer::
MAYBKM04101.250
Beschreibung:
6-chloro-1,4-dimethyl-3-(2-thienyl)-1H-p 1 * 250 mg
VE:
1 * 250 mg
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Artikel-Nr:
(PRSI26-278)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-278
Lokale Artikelnummer::
PRSI26-278
Beschreibung:
AKT1S1 may play an important role in phosphatidylinositol 3-kinase (PI3K)-AKT1 survival signaling. It is the substrate for AKT1 phosphorylation, but can also be activated by AKT1-independent mechanisms. Its role in survival signaling pathways may be modulated by oxidative stress. AKT1S1 may also play a role in nerve growth factor-mediated neuroprotection.AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]).
VE:
1 * 50 µG
Preis auf Anfrage
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