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Dimethyl+bicyclo[2.1.1]hexane-1,4-dicarboxylate
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Dimethyl+bicyclo[2.1.1]hexane-1,4-dicarboxylate
Artikel-Nr:
(ACRO200132500)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
200132500
Lokale Artikelnummer::
ACRO200132500
Beschreibung:
(±)-1,2-Hexandiol 98%
VE:
1 * 250 g
Lieferant:
BLD PHARMATECH GMBH
Beschreibung:
2,5-Diazabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester 97%
Artikel-Nr:
(78513-50G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
78513-50G
Lokale Artikelnummer::
SUPL78513-50G
Beschreibung:
D(-)-Mannitol, Supelco®
VE:
1 * 50 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Boc-3-exo-aminobicyclo[2.2.1]hept-5-ene-2-exo-carboxylic acid
Artikel-Nr:
(BOSSBS-9190R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9190R-A488
Lokale Artikelnummer::
BOSSBS-9190R-A488
Beschreibung:
Schlafen family members are preferentially expressed in lymphoid tissues and are differentially regulated during thymocyte maturation. Schlafen proteins function as suppressors of cell growth and are thought to play a role in the maintenance of T cell quiescence. The prototype member of the Schlafen family, Slfn1, is transcriptionally unregulated during thymocyte positive selection, and the induction of Slfn1 induces a G0/G1 arrest, suggesting that Slfn1 participates in the regulation of cell cycle and potentially acts as a determining factor for apoptosis. These proteins all contain a largely conserved core domain within the center of the sequence, and yet they are substantially diversified at the N terminus. Slfn14 (Schlafen family member 14) is a 912 amino acid protein belonging to the Schlafen family. Slfn14 exists as two alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 17q12.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9190R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9190R-A350
Lokale Artikelnummer::
BOSSBS-9190R-A350
Beschreibung:
Schlafen family members are preferentially expressed in lymphoid tissues and are differentially regulated during thymocyte maturation. Schlafen proteins function as suppressors of cell growth and are thought to play a role in the maintenance of T cell quiescence. The prototype member of the Schlafen family, Slfn1, is transcriptionally unregulated during thymocyte positive selection, and the induction of Slfn1 induces a G0/G1 arrest, suggesting that Slfn1 participates in the regulation of cell cycle and potentially acts as a determining factor for apoptosis. These proteins all contain a largely conserved core domain within the center of the sequence, and yet they are substantially diversified at the N terminus. Slfn14 (Schlafen family member 14) is a 912 amino acid protein belonging to the Schlafen family. Slfn14 exists as two alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 17q12.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9190R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9190R-FITC
Lokale Artikelnummer::
BOSSBS-9190R-FITC
Beschreibung:
Schlafen family members are preferentially expressed in lymphoid tissues and are differentially regulated during thymocyte maturation. Schlafen proteins function as suppressors of cell growth and are thought to play a role in the maintenance of T cell quiescence. The prototype member of the Schlafen family, Slfn1, is transcriptionally unregulated during thymocyte positive selection, and the induction of Slfn1 induces a G0/G1 arrest, suggesting that Slfn1 participates in the regulation of cell cycle and potentially acts as a determining factor for apoptosis. These proteins all contain a largely conserved core domain within the center of the sequence, and yet they are substantially diversified at the N terminus. Slfn14 (Schlafen family member 14) is a 912 amino acid protein belonging to the Schlafen family. Slfn14 exists as two alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 17q12.
VE:
1 * 100 µl
Lieferant:
VWR Chemicals
Beschreibung:
1-Hexansulfonsäure Natriumsalz ≥99%, HiPerSolv CHROMANORM® für die HPLC
Artikel-Nr:
(BOSSBS-12280R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12280R
Lokale Artikelnummer::
BOSSBS-12280R
Beschreibung:
Primordial germ cell (PGCs)-specific protein involved in epigenetic chromatin reprogramming in the zygote following fertilization. In zygotes, DNA demethylation occurs selectively in the paternal pronucleus before the first cell division, while the adjacent maternal pronucleus and certain paternally-imprinted loci are protected from this process. Participates in protection of DNA methylation in the maternal pronucleus by preventing conversion of 5mC to 5hmC: specifically recognizes and binds histone H3 dimethylated at 'Lys-9' (H3K9me2) on maternal genome, and protects maternal genome from TET3-mediated conversion to 5hmC and subsequent DNA demethylation. Does not bind paternal chromatin, which is mainly packed into protamine and does not contain much H3K9me2 mark. Also protects imprinted loci that are marked with H3K9me2 in mature sperm from DNA demethylation in early embryogenesis. May be important for the totipotent/pluripotent states continuing through preimplantation development. Also involved in chromatin condensation in oocytogenesis (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(PRSI5373)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5373
Lokale Artikelnummer::
PRSI5373
Beschreibung:
JMJD2A Antibody: Members of the Jumonji domain 2 (JMJD2) family contain a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. The first member of this group, JMJD2A, is widely expressed in human tissues and cell lines and functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor. JMJD2A can also form a complex with the androgen receptor (AR), a transcription factor that is pivotal for the development of prostate cancer. Overexpression of JMJD2A stimulates AR function and this stimulation is dependent on JMJD2A catalytic activity, suggesting that JMJD2A might be a critical protein with roles in cell proliferation and oncogenesis.
VE:
1 * 100 µG
Lieferant:
Thermo Scientific
Beschreibung:
(±)-2-Hexanol 99%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2,5-Diazabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester 95%
Lieferant:
Merck
Beschreibung:
1-Hexansulfonsäure Natriumsalz, LiChropur™ für die Ionenpaar-Chromatographie, Supelco®
Artikel-Nr:
(BOSSBS-3773R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3773R-CY5.5
Lokale Artikelnummer::
BOSSBS-3773R-CY5.5
Beschreibung:
Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11705R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11705R-CY3
Lokale Artikelnummer::
BOSSBS-11705R-CY3
Beschreibung:
AIP1 (ASK-interacting protein 1), also known as DAB2IP (DAB2 interacting protein), is a 1,189 amino acid protein that localizes to both the membrane and the cytoplasm and contains one Ras-GAP domain, one PH domain and one C2 domain. Expressed at low levels in prostate tissue, AIP1 functions as a Ras GTPase-activating protein that interacts with ASK 1 and, via this interaction, disrupts the association of ASK 1 with an inhibitory 14-3-3 complex, thereby allowing free ASK 1 to function within the cell. AIP1 exists as multiple alternatively spliced isoforms and is down-regulated in prostate cancer tissue, suggesting a role in tumor suppression. Chromosomal aberrations in the gene encoding AIP1 are associated with acute myeloid leukemia (AML), implicating a role for AIP1 fusion proteins in tumorigenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12253R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12253R
Lokale Artikelnummer::
BOSSBS-12253R
Beschreibung:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF219 (Zinc finger protein 219) is a 722 amino acid protein belonging to the Krüppel C2H2-type zinc-finger protein family. It is ubiquitously expressed and localizes to the nucleus. Containing 6 C2H2-type zinc fingers which function to bind DNA, ZNF219 is thought to be involved in transcriptional regulation. Specifically, ZNF219 has been identified as a transcriptional repressor that downregulates the transcription of the HMG-14 promoter.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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