Dimethyl+bicyclo[2.1.1]hexane-1,4-dicarboxylate
Lieferant:
Biotium
Beschreibung:
Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DR and DP. Human MHC class II antigens are transmembrane glycoproteins composed of an chain (36 kDa) and a chain (27 kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six and ten chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
An aminocyclitol antibiotic which acts by binding to the 30S subunit of the bacterial ribosome and inhibiting protein synthesis.
Artikel-Nr:
(BOSSBS-15561R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15561R-A750
Lokale Artikelnummer::
BOSSBS-15561R-A750
Beschreibung:
IFT20 is a gene encodes a intraflagellar transport protein important for intracellular transport. The encoded protein forms part of a complex involved in trafficking of proteins from the Golgi body, including recycling of immune signalling components. This gene is part of a complex set of sense-antisense loci that may be co-regulated. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 14.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3371R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3371R-A750
Lokale Artikelnummer::
BOSSBS-3371R-A750
Beschreibung:
The RAF family of signaling proteins has three isoforms: A RAF, RAF 1 and B RAF. These proteins are instrumental in forwarding the stimulus generated by mitogens from monomeric G proteins to the MAP kinase pathway. RAF 1 is known to be downstream of Ras and binds to it by an N terminal noncatalytic domain. This domain is conserved in A RAF and B RAF. 14-3-3 is also known to be an activator of RAFs. Activated RAF directly phosphorylates and activates MEK. A RAF is expressed at a very high concentration in urogenital and kidney tissues.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3005R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3005R-A680
Lokale Artikelnummer::
BOSSBS-3005R-A680
Beschreibung:
The RAF family of signaling proteins has three isoforms: A RAF, RAF 1 and B RAF. These proteins are instrumental in forwarding the stimulus generated by mitogens from monomeric G proteins to the MAP kinase pathway. RAF 1 is known to be downstream of Ras and binds to it by an N terminal noncatalytic domain. This domain is conserved in A RAF and B RAF. 14-3-3 is also known to be an activator of RAFs. Activated RAF directly phosphorylates and activates MEK. A RAF is expressed at a very high concentration in urogenital and kidney tissues.
VE:
1 * 100 µl
Artikel-Nr:
(SIAL52435-5ML)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
52435-5ML
Lokale Artikelnummer::
SIAL52435-5ML
Beschreibung:
cis-1,4-Hexadien, Sigma-Aldrich®
VE:
1 * 5 mL
Lieferant:
Thermo Scientific
Beschreibung:
3,4-Dimethylbenzaldehyd
Artikel-Nr:
(BOSSBS-1578R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1578R
Lokale Artikelnummer::
BOSSBS-1578R
Beschreibung:
The type I interferons consist of 14 different alpha isoforms (subtypes with slightly different specificities), and single beta, omega, epsilon and kappa isoforms. Homologous molecules are found in many species, including rats and mice (and most mammals), and have been identified in birds, reptiles and fish species. Interferon alpha is produced primarily by plasmacytoid dendritic cells and is a potent component of the anti viral innate immune response; it modulates adaptive immunity.
VE:
1 * 100 µl
Lieferant:
FLUOROCHEM
Beschreibung:
2,2,3,3-Tetrafluor-1,4-butandiol
Artikel-Nr:
(BOSSBS-3421R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3421R-CY7
Lokale Artikelnummer::
BOSSBS-3421R-CY7
Beschreibung:
The RAF family of signaling proteins has three isoforms: A RAF, RAF 1 and B RAF. These proteins are instrumental in forwarding the stimulus generated by mitogens from monomeric G proteins to the MAP kinase pathway. RAF 1 is known to be downstream of Ras and binds to it by an N terminal noncatalytic domain. This domain is conserved in A RAF and B RAF. 14-3-3 is also known to be an activator of RAFs. Activated RAF directly phosphorylates and activates MEK. A RAF is expressed at a very high concentration in urogenital and kidney tissues.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1966R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1966R-FITC
Lokale Artikelnummer::
BOSSBS-1966R-FITC
Beschreibung:
May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. Cleaves insulin A chain at '14-Tyr-|-Gln-15' and insulin B chain at '6-Leu-|-Cys-7', '16-Tyr-|-Leu-17', '25-Phe-|-Tyr-26' and '26-Tyr-|-Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1966R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1966R-A350
Lokale Artikelnummer::
BOSSBS-1966R-A350
Beschreibung:
May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. Cleaves insulin A chain at '14-Tyr-|-Gln-15' and insulin B chain at '6-Leu-|-Cys-7', '16-Tyr-|-Leu-17', '25-Phe-|-Tyr-26' and '26-Tyr-|-Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines.
VE:
1 * 100 µl
Artikel-Nr:
(SIALF1392-25MG)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
F1392-25MG
Lokale Artikelnummer::
SIALF1392-25MG
Beschreibung:
Riboflavin-5'-phosphat Natriumsalz Dihydrat, Sigma-Aldrich®
VE:
1 * 25 mg
Lieferant:
Bernd Kraft
Beschreibung:
2-Propanol ≥70% (v/v), reinst
Artikel-Nr:
(BOSSBS-3484R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3484R-CY5.5
Lokale Artikelnummer::
BOSSBS-3484R-CY5.5
Beschreibung:
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
VE:
1 * 100 µl
Preis auf Anfrage
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