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Dimethyl+bicyclo[2.1.1]hexane-1,4-dicarboxylate
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Dimethyl+bicyclo[2.1.1]hexane-1,4-dicarboxylate
Artikel-Nr:
(BOSSBS-12567R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12567R-CY3
Lokale Artikelnummer::
BOSSBS-12567R-CY3
Beschreibung:
Bad is a member of the Bcl2 family and acts to promote apoptosis by forming heterodimers with the survival proteins Bcl2 and BclxL, thus preventing them from binding with BAX. Bad is found on the outer mitochondrial membrane and, once phosphorylated in response to growth stimuli, translocates to the cytoplasm. The phosphorylation status of Bad represents a key checkpoint for death or cell survival. JNK-induced phosphorylation of BAD serine 128 promotes the apoptotic role of Bad by opposing the inhibitory effect of growth factor on Bad-mediated apoptosis. Cdc2-induced phosphorylation of Bad serine 128 has an inhibitory effect on its interaction with 14-3-3 proteins. The latter interaction is critical for Bad phosphorylation at serine 155, a site within the BH3 domain that leads to the release of BclxL and the promotion of cell survival. Alternative splicing of this gene results in two transcript variants which encode the same isoform.This antibody recognise the phosphorylation site of human Ser75, mouse Ser111, rat Ser112.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6073R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6073R-A555
Lokale Artikelnummer::
BOSSBS-6073R-A555
Beschreibung:
Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function. Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain. Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fatty acids such LPC oleate and LPC palmitate with a minimum acyl chain length of 14 carbons. Does not transport docosahexaenoic acid in unesterified fatty acid. Specifically required for blood-brain barrier formation and function, probably by mediating lipid transport. Not required for central nervous system vascular morphogenesis (By similarity). Acts as a transporter for tunicamycin, an inhibitor of asparagine-linked glycosylation. In placenta, acts as a receptor for ERVFRD-1/syncytin-2 and is required for trophoblast fusion (PubMed:18988732).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9740R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9740R-A680
Lokale Artikelnummer::
BOSSBS-9740R-A680
Beschreibung:
CNTD2 (cyclin N-terminal domain containing 2) is a 155 amino acid protein that contains one cyclin N-terminal domain and is encoded by a gene that maps to human chromosome 19q13.2. Chromosome 19 consists of approximately 63 million bases and makes up over 2% of human genomic DNA. Chromosome 19 is recognised for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members, including killer cell and leukocyte Ig-like receptors, various ICAMs, the CEACAM and PSG families, and Fc receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene Bcl-3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9740R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9740R-A488
Lokale Artikelnummer::
BOSSBS-9740R-A488
Beschreibung:
CNTD2 (cyclin N-terminal domain containing 2) is a 155 amino acid protein that contains one cyclin N-terminal domain and is encoded by a gene that maps to human chromosome 19q13.2. Chromosome 19 consists of approximately 63 million bases and makes up over 2% of human genomic DNA. Chromosome 19 is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members, including killer cell and leukocyte Ig-like receptors, various ICAMs, the CEACAM and PSG families, and Fc?receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene Bcl-3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3655R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3655R
Lokale Artikelnummer::
BOSSBS-3655R
Beschreibung:
This gene is a member of the kernel lipocalin superfamily whose members share relatively low sequence similarity but have highly conserved exon/intron structure and three-dimensional protein folding. Most lipocalins are clustered on the long arm of chromosome 9. The encoded glycoprotein has been previously referred to as pregnancy-associated endometrial alpha-2-globulin, placental protein 14, and glycodelin, but has been officially named progestagen-associated endometrial protein. Three distinct forms, with identical protein backbones but different glycosylation profiles, are found in amniotic fluid, follicular fluid and seminal plasma of the reproductive system. These glycoproteins have distinct and essential roles in regulating a uterine environment suitable for pregnancy and in the timing and occurrence of the appropriate sequence of events in the fertilization process. A number of alternatively spliced transcript variants have been observed at this locus, but the full-length nature of only two, each encoding the same protein, has been determined. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BSBTPB9033)
Lieferant:
BosterBio
Hersteller-Artikelnummer::
PB9033
Lokale Artikelnummer::
BSBTPB9033
Beschreibung:
Polyclonal antibody for COFILIN/CFL1 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: ELISA. Reactive species: Human. COFILIN/CFL1 information: Molecular Weight: 18502 MW; Subcellular Localization: Nucleus matrix . Cytoplasm, cytoskeleton . Cell projection, ruffle membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, lamellipodium membrane ; Peripheral membrane protein ; Cytoplasmic side . Colocalizes with the actin cytoskeleton in membrane ruffles and lamellipodia. Detected at the cleavage furrow and contractile ring during cytokinesis. Almost completely in nucleus in cells exposed to heat shock or 10% dimethyl sulfoxide; Tissue Specificity: Widely distributed in various tissues.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI3275P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3275P
Lokale Artikelnummer::
PRSI3275P
Beschreibung:
TLR10 peptide is used for blocking the activity of the TLR10 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI4489P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4489P
Lokale Artikelnummer::
PRSI4489P
Beschreibung:
LGI1 peptide is used for blocking the activity of LGI1 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI3107P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3107P
Lokale Artikelnummer::
PRSI3107P
Beschreibung:
Ipaf peptide is used for blocking the activity of Ipaf antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI5869P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5869P
Lokale Artikelnummer::
PRSI5869P
Beschreibung:
AFP peptide is used for blocking the activity of AFP antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI4545P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4545P
Lokale Artikelnummer::
PRSI4545P
Beschreibung:
IRGM peptide is used for blocking the activity of IRGM antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI4623P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4623P
Lokale Artikelnummer::
PRSI4623P
Beschreibung:
SAPAP1 peptide is used for blocking the activity of SAPAP1 antibody.
VE:
1 * 50 µG
Lieferant:
Sigma-Aldrich
Beschreibung:
PIPES, Sigma-Aldrich®
Lieferant:
Biotium
Beschreibung:
Recognizes the L1 or Calprotectin molecule, an intra-cytoplasmic antigen comprising of a 12 kDa alpha chain and a 14 kDa beta chain. Calprotectin comprises 60% of the cytoplasmic protein fraction of circulating polymorphonuclear granulocytes and is also found in monocytes, macrophages and ileal tissue eosinophils. Peripheral blood monocytes carry the antigen extra- and intracellularly, neutrophils only intracellularly. Calprotectin has antibacterial, antifungal, immunomodulating and antiproliferative effects. Besides this it is a potent chemotactic factor for neutrophils. Plasma concentrations are elevated in diseases associated with increased neutrophil activity, like inflammatory bowel disease. Granulocytes terminate their existence after transmigration through the intestinal wall. Therefore calprotectin is also detectable in feces. Elevated levels of calprotectin have been observed in body fluids such as plasma, saliva, gingival crevicular fluid, stools, and synovial fluid during infection and inflammatory conditions.This MAb reacts with neutrophils, monocytes, macrophages, and squamous mucosal epithelia and is important for identifying macrophages in tissue sections.
Lieferant:
Thermo Scientific
Beschreibung:
HEPES Natriumsalz 99%
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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