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3,5-Dichloro-4-fluorophenol
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3,5-Dichloro-4-fluorophenol
Artikel-Nr:
(WAKO242-00462)
Lieferant:
Wako
Hersteller-Artikelnummer::
242-00462
Lokale Artikelnummer::
WAKO242-00462
Beschreibung:
Xylencyanol FF
VE:
1 * 25 g
 This is a MarketSource item. Additional charges may apply
Lieferant:
Sigma-Aldrich
Beschreibung:
2-Brom-2-buten (Gemisch der cis- und trans-Isomeren), Sigma-Aldrich®
Artikel-Nr:
(BOSSBS-13664R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13664R-HRP
Lokale Artikelnummer::
BOSSBS-13664R-HRP
Beschreibung:
The eight members of the recently identified Suppressor of Cytokines Signaling (SOCS) family are SOCS1, SOCS2, SOCS3, SOCS4, SOCS5, SOCS6, SOCS7, and CIS. Structurally the SOCS proteins are composed of an N- terminal region of variable length and amino acid composition, a central SH2 domain, and a C-terminal motif called the SOCS box. The SOCS proteins appear to form part of a classical negative feedback loop that regulates cytokine signal transduction. Transcription of each of the SOCS genes occurs rapidly in vitro and in vivo in response to cytokines, and once produced, the various members of the SOCS family appear to inhibit signaling in different ways. During Th1 differentiation a reduction in the association of Jak1 with the IL4 Receptor correlated with the appearance of SOCS5. SOCS5 protein was preferentially expressed in committed Th1 cells and interacted with the cytoplasmic region of the IL4 Receptor alpha chain irrespective of receptor tyrosine phosphorylation. This unconventional interaction of SOCS5 protein with IL4 Receptor resulted in the inhibition of IL4-mediated signal transducer and activator of transcription-6 activation. T cells from transgenic mice constitutively expressing SOCS5 exhibited a significant reduction of IL4-mediated Th2 development. Therefore, the induced SOCS5 protein in Th1 differentiation environment may play an important role by regulating Th1 and Th2 balance.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI91-195)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-195
Lokale Artikelnummer::
PRSI91-195
Beschreibung:
Cyclophilin C is an enzyme (EC 5.2.1.8) found in both prokaryotes and eukaryotes that interconverts the cis and trans isomers of peptide bonds with the amino acid proline. Proline has an unusually conformationally restrained peptide bond due to its cyclic structure with its side chain bonded to its secondary amine nitrogen. Most amino acids have a strong energetic preference for the trans peptide bond conformation due to steric hindrance, but prolines unusual structure stabilizes the cis form so that both isomers are populated under biologically relevant conditions. Proteins with prolyl isomerase activity include cyclophilin, FKBPs, and parvulin, although larger proteins can also contain prolyl isomerase domains.
VE:
1 * 50 µG
Lieferant:
VARIAN
Beschreibung:
Garantierte Analyse der FAME-cis/trans-Isomere für absolute Sicherheit.
Artikel-Nr:
(MOLE45545810)
Lieferant:
Molekula
Hersteller-Artikelnummer::
45545810
Lokale Artikelnummer::
MOLE45545810
Beschreibung:
Brillantkresylblau
VE:
1 * 25 g
Artikel-Nr:
(PRSI26-725)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-725
Lokale Artikelnummer::
PRSI26-725
Beschreibung:
RDH12 is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. RDH12 also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3).The protein encoded by this gene is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. The encoded enzyme also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3).
VE:
1 * 50 µG
Artikel-Nr:
(SERA27215.01)
Lieferant:
Serva
Hersteller-Artikelnummer::
27215.01
Lokale Artikelnummer::
SERA27215.01
Beschreibung:
Kongorot
VE:
1 * 25 g
This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BOSSBS-13664R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13664R-CY3
Lokale Artikelnummer::
BOSSBS-13664R-CY3
Beschreibung:
The eight members of the recently identified Suppressor of Cytokines Signaling (SOCS) family are SOCS1, SOCS2, SOCS3, SOCS4, SOCS5, SOCS6, SOCS7, and CIS. Structurally the SOCS proteins are composed of an N- terminal region of variable length and amino acid composition, a central SH2 domain, and a C-terminal motif called the SOCS box. The SOCS proteins appear to form part of a classical negative feedback loop that regulates cytokine signal transduction. Transcription of each of the SOCS genes occurs rapidly in vitro and in vivo in response to cytokines, and once produced, the various members of the SOCS family appear to inhibit signaling in different ways. During Th1 differentiation a reduction in the association of Jak1 with the IL4 Receptor correlated with the appearance of SOCS5. SOCS5 protein was preferentially expressed in committed Th1 cells and interacted with the cytoplasmic region of the IL4 Receptor alpha chain irrespective of receptor tyrosine phosphorylation. This unconventional interaction of SOCS5 protein with IL4 Receptor resulted in the inhibition of IL4-mediated signal transducer and activator of transcription-6 activation. T cells from transgenic mice constitutively expressing SOCS5 exhibited a significant reduction of IL4-mediated Th2 development. Therefore, the induced SOCS5 protein in Th1 differentiation environment may play an important role by regulating Th1 and Th2 balance.
VE:
1 * 100 µl
Lieferant:
Sigma-Aldrich
Beschreibung:
Crotylalkohol (Gemisch der cis- und trans-Isomeren), Sigma-Aldrich®
Artikel-Nr:
(SIAL117641-500G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
117641-500G
Lokale Artikelnummer::
SIAL117641-500G
Beschreibung:
3-Aminocrotononitril ≥96%, Sigma-Aldrich®
VE:
1 * 500 g
Artikel-Nr:
(BOSSBS-13664R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13664R-A350
Lokale Artikelnummer::
BOSSBS-13664R-A350
Beschreibung:
The eight members of the recently identified Suppressor of Cytokines Signaling (SOCS) family are SOCS1, SOCS2, SOCS3, SOCS4, SOCS5, SOCS6, SOCS7, and CIS. Structurally the SOCS proteins are composed of an N- terminal region of variable length and amino acid composition, a central SH2 domain, and a C-terminal motif called the SOCS box. The SOCS proteins appear to form part of a classical negative feedback loop that regulates cytokine signal transduction. Transcription of each of the SOCS genes occurs rapidly in vitro and in vivo in response to cytokines, and once produced, the various members of the SOCS family appear to inhibit signaling in different ways. During Th1 differentiation a reduction in the association of Jak1 with the IL4 Receptor correlated with the appearance of SOCS5. SOCS5 protein was preferentially expressed in committed Th1 cells and interacted with the cytoplasmic region of the IL4 Receptor alpha chain irrespective of receptor tyrosine phosphorylation. This unconventional interaction of SOCS5 protein with IL4 Receptor resulted in the inhibition of IL4-mediated signal transducer and activator of transcription-6 activation. T cells from transgenic mice constitutively expressing SOCS5 exhibited a significant reduction of IL4-mediated Th2 development. Therefore, the induced SOCS5 protein in Th1 differentiation environment may play an important role by regulating Th1 and Th2 balance.
VE:
1 * 100 µl
Artikel-Nr:
(PIER20504)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
20504
Lokale Artikelnummer::
PIER20504
Beschreibung:
Thermo Scientific Pierce Sodium meta-Periodate is a gentle oxidizing agent that cleaves cis-diols in carbohydrate sugars to create amine-reactive aldehydes, providing many uses relating to the study and detection of glycoproteins.
VE:
1 * 25 g
Lieferant:
Biotium
Beschreibung:
This MAb recognizes a protein of 134 kDa, which binds fibroblast growth factor and E-selectin (cell-adhesion lectin on endothelial cells mediating the binding of neutrophils). Fucosylation is essential for binding to E-selectin. It contains sialic acid residues and 16 Cys-rich GLG1 repeats. This MAb can be used to stain the Golgi complex in cell or tissue preparations and can be used as a Golgi marker in subcellular fractions. It produces a diffuse staining pattern of the Golgi zone in normal and malignant cells. This MAb is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells. The Golgi apparatus is an organelle present in all eukaryotic cells that forms a part of the endomembrane system. The primary function of the Golgi apparatus is to process and package macromolecules synthesized by the cell for exocytosis or use within the cell. The Golgi is made up of a stack of flattened, membrane-bound sacs known as cisternae, with three functional regions: the cis face, medial region and trans face. Each region consists of various enzymes that selectively modify the macromolecules passing though them, depending on where they are destined to reside. Several spherical vesicles that have budded off of the Golgi are present surrounding the main cisternae. The Golgi tends to be more pronounced and numerous in cells that make and secrete many substances such as plasma B cells.
Lieferant:
Sigma-Aldrich
Beschreibung:
Isophorondiisocyanat (Gemisch der cis- und trans-Isomeren), Sigma-Aldrich®
Artikel-Nr:
(SIAL403733-250ML)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
403733-250ML
Lokale Artikelnummer::
SIAL403733-250ML
Beschreibung:
1,3-Dichlorpropen (Gemisch der cis- und trans-Isomeren), Sigma-Aldrich®
VE:
1 * 250 mL
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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