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2-(2-Fluorophenyl)-3-oxobutanenitrile
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2-(2-Fluorophenyl)-3-oxobutanenitrile
Artikel-Nr:
(BOSSBS-1764R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1764R-HRP
Lokale Artikelnummer::
BOSSBS-1764R-HRP
Beschreibung:
Receptor tyrosine kinase which binds membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Highly promiscuous, it has the unique property among Eph receptors to bind and to be physiologically activated by both GPI-anchored ephrin-A and transmembrane ephrin-B ligands including EFNA1 and EFNB3. Upon activation by ephrin ligands, modulates cell morphology and integrin-dependent cell adhesion through regulation of the Rac, Rap and Rho GTPases activity. Plays an important role in the development of the nervous system controlling different steps of axonal guidance including the establishment of the corticospinal projections. May also control the segregation of motor and sensory axons during neuromuscular circuit development. In addition to its role in axonal guidance plays a role in synaptic plasticity. Activated by EFNA1 phosphorylates CDK5 at 'Tyr-15' which in turn phosphorylates NGEF regulating RHOA and dendritic spine morphogenesis. In the nervous system, plays also a role in repair after injury preventing axonal regeneration and in angiogenesis playing a role in central nervous system vascular formation. Additionally, its promiscuity makes it available to participate in a variety of cell-cell signaling regulating for instance the development of the thymic epithelium.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0573R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0573R-A488
Lokale Artikelnummer::
BOSSBS-0573R-A488
Beschreibung:
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in cell-cycle regulated histone gene expression and plays a critical role in promoting cell-cycle progression in the absence of pRB. Two alternatively spliced transcript variants of this gene, which encode distinct isoforms, have been described. Two additional splice variants were reported but detailed nucleotide sequence information is not yet available. Transcript Variant: This variant (1) contains a different 5' end region, which includes an upstream in-frame translation start codon, when compared to variant 2. The encoded protein has a 15 aa longer N-terminus, as compared to isoform 2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0573R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0573R-A750
Lokale Artikelnummer::
BOSSBS-0573R-A750
Beschreibung:
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterised by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in cell-cycle regulated histone gene expression and plays a critical role in promoting cell-cycle progression in the absence of pRB. Two alternatively spliced transcript variants of this gene, which encode distinct isoforms, have been described. Two additional splice variants were reported but detailed nucleotide sequence information is not yet available. Transcript Variant: This variant contains a different 5' end region, which includes an upstream in-frame translation start codon, when compared to variant 2. The encoded protein has a 15 aa longer N-terminus, as compared to isoform 2.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI28-283)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-283
Lokale Artikelnummer::
PRSI28-283
Beschreibung:
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7 is located on chromosome 15 in a region associated with several neuropsychiatric disorders. CHRFAM7A is is a hybrid between CHRNA7 and FAM7A.
VE:
1 * 50 µG
Artikel-Nr:
(SCERSP73500-16100A)
Lieferant:
DWK Life Sciences
Hersteller-Artikelnummer::
SP73500-16100A
Lokale Artikelnummer::
SCERSP73500-16100A
Beschreibung:
Culture tubes made from 51 expansion borosilicate glass that offer excellent chemical resistance against sodium leaching, a factor common in soda lime glass products.
VE:
1 * 1.000 ST
Lieferant:
Sigma-Aldrich
Beschreibung:
Bernsteinsäure, Sigma-Aldrich®
Lieferant:
MP Biomedicals
Beschreibung:
Lysing Matrix Z is used primarily for lysis of animal and plant tissue, tougher stems, roots and seeds, and whole insects. Each impact-resistant tube contains yttria-stabilised zirconium oxide beads.
Artikel-Nr:
(EHERC16003100)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C16003100
Lokale Artikelnummer::
EHERC16003100
Beschreibung:
Phenazon
VE:
1 * 0,25 g
Lieferant:
DWK Life Sciences
Beschreibung:
The Nessler tubes, with shadowless bottom that transmits undistorted light, are ideal for colour comparison. Rings and markings are in durable white ceramic enamel which correspond with specific volumes of liquid. Graduated ring scale of any of the tubes within a set will not vary from that of any other tube within the set by more than 1,5 mm.
Artikel-Nr:
(HONCR1142-25MG)
Lieferant:
Honeywell Chemicals
Hersteller-Artikelnummer::
R1142-25MG
Lokale Artikelnummer::
HONCR1142-25MG
Beschreibung:
High quality inorganic and organic reference materials produced according to ISO 9001.
VE:
1 * 25 mg
Artikel-Nr:
(111-1753)
Lieferant:
Bollé Safety
Hersteller-Artikelnummer::
IRIDPSI1.5
Lokale Artikelnummer::
BOLEIRIDPSI1.5
Beschreibung:
Diese universellen Schutzbrillen sind ultramodular und passen sich dank des B-Flex Nasenstegs mit Formgedächtnis jedem Träger an.
VE:
1 * 1 ST
Lieferant:
IKA
Beschreibung:
Glass or PTFE-coated stirring bars. Used in wide range of applications. Available in 5/set or 1/set.
Artikel-Nr:
(NEWPPLPE270)
Lieferant:
NEW PIG
Hersteller-Artikelnummer::
PLPE270
Lokale Artikelnummer::
NEWPPLPE270
Beschreibung:
PIG® FIRE-DRI is a granular organic product, suitable for a wide range of industrial applications. With its fireproof property, it can be used for liquids and applications where the use of fire resistant products is desired.
VE:
1 * 6 kg
Artikel-Nr:
(NSCAC4015-4)
Lieferant:
THERMO NATIONAL SCIENTIFIC
Hersteller-Artikelnummer::
C4015-4
Lokale Artikelnummer::
NSCAC4015-4
Beschreibung:
Originale Waters™ 4 ml WISP™-Autosampler Rollrand-/Schnappdeckelgläschen Qualitativ hochwertiges 33 Expansion Borosilikat-Klarglas (Typ 1, Klasse A) mit Flachboden.
VE:
1 * 100 ST
Artikel-Nr:
(MOLEM62132853)
Lieferant:
Molekula
Hersteller-Artikelnummer::
M62132853
Lokale Artikelnummer::
MOLEM62132853
Beschreibung:
2-Fluorphenylhydraziniumchlorid
VE:
1 * 5 g
 This is a MarketSource item. Additional charges may apply
Lieferant:
COMBI-BLOCKS
Beschreibung:
3-(3,4-Difluorphenylcarbamoyl)phenylboronsäure
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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