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Sulindac+sulphone-acyl-\u03B2-D-glucuronide
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Sulindac+sulphone-acyl-\u03B2-D-glucuronide
Artikel-Nr:
(BOSSBS-8414R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8414R-A555
Lokale Artikelnummer::
BOSSBS-8414R-A555
Beschreibung:
The hydroxyacylglutathione hydrolase-like protein (HAGHL) is a 290 amino acid protein that belongs to the glyoxalase II family. HAGHL binds two zinc ions per subunit and acts as a hydrolase on ester bonds. The gene encoding HAGHL maps to human chromosome 16, which encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The rare disorder Rubinstein-Taybi syndrome is associated with chromosome 16, as is Crohn's disease, a gastrointestinal inflammatory condition that may involve the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier.
VE:
1 * 100 µl
Artikel-Nr:
(MOLE10332118-1G)
Lieferant:
Molekula
Hersteller-Artikelnummer::
10332118-1G
Lokale Artikelnummer::
MOLE10332118-1G
Beschreibung:
1,1'-Bis(diphenylphosphino)ferrocen
VE:
1 * 1 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BOSSBS-5560R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5560R-A647
Lokale Artikelnummer::
BOSSBS-5560R-A647
Beschreibung:
Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(48567.)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
48567
Lokale Artikelnummer::
SUPL48567
Beschreibung:
Anthracen
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-13153R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13153R-A680
Lokale Artikelnummer::
BOSSBS-13153R-A680
Beschreibung:
FDPS is a 419 amino acid enzyme belonging to the FPP/GGPP synthetase family. Localized to cytoplasm and peroxisome, FDPS expression is regulated by phorbol esters and polyunsaturated fatty acids. FDPS assists in cholesterol biosynthesis, post-translational protein modifications and synthesis of steroid hormones in the isoprenoid pathway.FDPS catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FDPS is inactivated by interferon-induced RSAD2, which may result in the disruption of lipid rafts at the plasma membrane. Existing as a homodimer, FDPS may have anti-viral effects when inactivated by RSAD2. Reduced activity of FDPS in liver may partly be the cause of Zellweger syndrome and neonatal adrenoleukodystrophy, both of which are known to be peroxisomal deficiency diseases.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12405R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12405R-FITC
Lokale Artikelnummer::
BOSSBS-12405R-FITC
Beschreibung:
Mitogen-activated protein kinase (MAPK) signaling pathways involve closely related MAP kinases, including extracellular-signal-related kinase 3 (ERK 3, also designated PRKM6 and p97MAPK). Serum, growth factors and phorbol esters can initiate ERK 3 signaling pathways. Despite lacking a definitive nuclear localization sequence, ERK 3 constitutively localizes to the nucleus upon activation. p38 pathway activation-dependent upregulation of ERK 3 is independent of the status of p53, Bcl-2 and caspase-3 during cell stress and damage induced by proteasome inhibition, suggesting ERK 3 in part mediates intracellular defense or cell rescue. The human ERK 3 gene maps to chromosome 15q21.2 and encodes a 721 amino acid protein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12405R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12405R-A647
Lokale Artikelnummer::
BOSSBS-12405R-A647
Beschreibung:
Mitogen-activated protein kinase (MAPK) signaling pathways involve closely related MAP kinases, including extracellular-signal-related kinase 3 (ERK 3, also designated PRKM6 and p97MAPK). Serum, growth factors and phorbol esters can initiate ERK 3 signaling pathways. Despite lacking a definitive nuclear localization sequence, ERK 3 constitutively localizes to the nucleus upon activation. p38 pathway activation-dependent upregulation of ERK 3 is independent of the status of p53, Bcl-2 and caspase-3 during cell stress and damage induced by proteasome inhibition, suggesting ERK 3 in part mediates intracellular defense or cell rescue. The human ERK 3 gene maps to chromosome 15q21.2 and encodes a 721 amino acid protein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6425R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6425R-CY3
Lokale Artikelnummer::
BOSSBS-6425R-CY3
Beschreibung:
Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH, citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers. Acts as a regulator of intracellular Ca(2+) in synoviocytes. Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12,13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8.
VE:
1 * 100 µl
Artikel-Nr:
(BLDPBD00782247-100)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD00782247-100
Lokale Artikelnummer::
BLDPBD00782247-100
Beschreibung:
4-(6-(4-Methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)benzene-1,2-diamine trihydrochloride 98%
VE:
1 * 100 mg
Artikel-Nr:
(ACRO268780025)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
268780025
Lokale Artikelnummer::
ACRO268780025
Beschreibung:
Tetrabutylammoniumdihydrogentrifluorid 50-55% (w/w) in 1,2-Dichloroethan
VE:
1 * 2,5 g
Artikel-Nr:
(317240-5)
Lieferant:
Merck Millipore (Calbiochem)
Hersteller-Artikelnummer::
317240-5
Lokale Artikelnummer::
CALB317240-5
Beschreibung:
1,1-Dimethylbiguanid Hydrochlorid, Millipore®
VE:
1 * 5 g
Lieferant:
MP Biomedicals
Beschreibung:
1,1-Dimethylbiguanide hydrochloride is suitable biguanide agent used in a study to investigate its role in enhancing the secretions of plasma active glucagon-like peptide-1 (GLP-1) levels.
Artikel-Nr:
(APOSOR27433-250MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR27433-250MG
Lokale Artikelnummer::
APOSOR27433-250MG
Beschreibung:
2,6-Dichloro-4-[5-(1,2-oxazol-5-yl)-1,3,4-oxadiazol-2-yl]pyridine
VE:
1 * 250 mg
Lieferant:
Alfa Aesar
Beschreibung:
Aluminium, Perlen ACS 8-12 mm (0.31-0.47 in)
Artikel-Nr:
(BLDPBD00930763-1G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD00930763-1G
Lokale Artikelnummer::
BLDPBD00930763-1G
Beschreibung:
(4,4,9,9-Tetrakis(4-hexylphenyl)-4,9-dihydro-s-indaceno[1,2-b:5,6-b']dithiophene-2,7-diyl)bis(trimethylstannane) 97%
VE:
1 * 1 g
Artikel-Nr:
(BLDPBD01277948-250)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD01277948-250
Lokale Artikelnummer::
BLDPBD01277948-250
Beschreibung:
(3aS,8aR)-2-(1,8-Naphthyridin-2-yl)-8,8a-dihydro-3aH-indeno[1,2-d]oxazole 97%
VE:
1 * 250 mg
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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