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2,4,6-Tris(brommethyl)mesitylen
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2,4,6-Tris(brommethyl)mesitylen
Artikel-Nr:
(BOSSBS-7541R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7541R-FITC
Lokale Artikelnummer::
BOSSBS-7541R-FITC
Beschreibung:
Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8165R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8165R-CY7
Lokale Artikelnummer::
BOSSBS-8165R-CY7
Beschreibung:
Plays a role as a modulator of TGF-beta-signaling by restricting substrate specificity of RNF111. Involved in autophagy. Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1. Required for the formation of the autophagosome-like double-membrane structure that surrounds the Salmonella-containing vacuole (SCV) duting S.typhimurium infection and subsequent xenophagy. Autophagy positively regulates repair of DNA damage induced by ionizing radiation and negatively regulates apoptosis. Plays an indispensible role in fetal hematopoiesis and in the regulation of neuronal homeostasis (By similarity). Implicated in the regulation of RB1 expression. Functions as a DNA-binding transcription factor. Is a potent regulator of the RB1 pathway and a mediator that plays a crucial role in muscular differentiation. Expression is, thus, a prerequisite for myogenic differentiation. Inhibits PTK2/FAK1 and PTK2B/PYK2 activity and activation of downstream signaling pathways.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1110R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1110R-CY5.5
Lokale Artikelnummer::
BOSSBS-1110R-CY5.5
Beschreibung:
Transcriptional activator essential for osteoblast differentiation. Binds to SP1 and EKLF consensus sequences and to other G/C-rich sequences (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11936R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11936R-CY3
Lokale Artikelnummer::
BOSSBS-11936R-CY3
Beschreibung:
Forms a receptor complex with neuropilin-1 and can propagate semaphorin-3A elicited inhibitory signals into cells and neurons.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10466R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10466R-A488
Lokale Artikelnummer::
BOSSBS-10466R-A488
Beschreibung:
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein facilitates translocation of a functional guanine nucleotide exchange factor (GEF) complex from the cytoplasm to the plasma membrane where ras-related C3 botulinum toxin substrate 1 is activated to promote lamellipodium formation and cell migration. Two related pseudogene have been identified on chromosomes 20 and X. [provided by RefSeq, Aug 2011].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13084R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13084R-A488
Lokale Artikelnummer::
BOSSBS-13084R-A488
Beschreibung:
EPHEXIN is a 710 amino acid protein that localizes to both the membrane and the cytoplasm and contains one SH3 domain, one PH domain and one DH domain. Expressed at high levels in brain and present at lower levels in lung tissue, EPHEXIN interacts with EphA4 and functions as a guanine nucleotide exchange factor (GEF) that is capable of activating Rho A, Rac 1 and Cdc42 and is thought to play a role in axon guidance and growth cone collapse. EPHEXIN is subject to Src-dependent phosphorylation, an event that increases the GEF activity of EPHEXIN toward Rho A. Human EPHEXIN, which exists as multiple alternatively spliced isoforms, shares a high degree of sequence homology with its mouse counterpart, suggesting a conserved role between species.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13090R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13090R-CY7
Lokale Artikelnummer::
BOSSBS-13090R-CY7
Beschreibung:
This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6804R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6804R-CY5
Lokale Artikelnummer::
BOSSBS-6804R-CY5
Beschreibung:
This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9602R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9602R-A647
Lokale Artikelnummer::
BOSSBS-9602R-A647
Beschreibung:
This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11210R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11210R
Lokale Artikelnummer::
BOSSBS-11210R
Beschreibung:
Dyneins are multisubunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein heavy, intermediate, light and light-intermediate chains are all components of minus end-directed motors; the complex transports cellular cargos towards the central region of the cell. Axonemal dynein motors contain one to three non-identical heavy chains and cause a sliding of microtubules in the axonemes of cilia and flagella in a mechanism necessary for cilia to beat and propel the cell. DNAH9 (Dynein, axonemal, heavy chain 9), also known as DYH9, HL20, DNEL1, Dnahc9 or DNAH17L, is a member of the Dynein heavy chain family and comprises one of the heavy chain subunits of axonemal Dynein. DNAH9 consists of an N-terminal stem which is responsible for interacting with other Dynein components and binding cargo, and four P-loops that comprise the motor domain at its C-terminus.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11526R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11526R
Lokale Artikelnummer::
BOSSBS-11526R
Beschreibung:
The galanin family of proteins are key members for inflammatory processes and cell proliferation, and may function as potential biomarkers for colon cancer. Produced in both neuronal and nonneuronal cells in the skin, members of the galanin family include galanin, galanin-message associated peptide, galanin-like peptide and alarin. GALP, also known as galanin-like peptide, is a 116 amino acid secreted protein belonging to the galanin family. Mainly produced in the arcuate nucleus of the hypothalamus (ARC) and the posterior pituitary, GALP is thought to function in CNS homeostatic processes, including the regulation of gonadotropin-releasing hormone secretion. GALP binds to the G-protein coupled galanin receptors, including GALR1, GALR2 and GALR3, and may also play a role in energy metabolism, with significant implications towards obesity. GALP exits as two alternatively spliced isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4204R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4204R-CY3
Lokale Artikelnummer::
BOSSBS-4204R-CY3
Beschreibung:
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Several alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2377R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2377R-HRP
Lokale Artikelnummer::
BOSSBS-2377R-HRP
Beschreibung:
Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone homeostasis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2366R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2366R-A647
Lokale Artikelnummer::
BOSSBS-2366R-A647
Beschreibung:
The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. HSD VII is active against four 7-alpha-hydroxylated sterols. Does not metabolize several different C(19/21) steroids as substrates. Involved in bile acid synthesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3909R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3909R-CY5.5
Lokale Artikelnummer::
BOSSBS-3909R-CY5.5
Beschreibung:
Acts together with cubilin to mediate HDL endocytosis (By similarity). May participate in regulation of parathyroid-hormone and para-thyroid-hormone-related protein release.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3996R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3996R-HRP
Lokale Artikelnummer::
BOSSBS-3996R-HRP
Beschreibung:
Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. Malate dehydrogenase 1 (MDH1) is localized to the cytoplasm and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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