Ethyl-2-naphthoyl+formate
Artikel-Nr:
(APOSPC512001-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC512001-1G
Lokale Artikelnummer::
APOSPC512001-1G
Beschreibung:
2,2,2-Trifluoro-N-[1-(4-fluorophenyl)ethyl]ethanamine hydrochloride
VE:
1 * 1 g
Artikel-Nr:
(APOSOR480018-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR480018-1G
Lokale Artikelnummer::
APOSOR480018-1G
Beschreibung:
Ethyl 5-amino-4-chloro-1-(1-ethylpropyl)pyrazole-3-carboxylate
VE:
1 * 1 g
Artikel-Nr:
(APOSOR480021-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR480021-1G
Lokale Artikelnummer::
APOSOR480021-1G
Beschreibung:
Ethyl 5-amino-4-chloro-1-isobutyl-pyrazole-3-carboxylate
VE:
1 * 1 g
Artikel-Nr:
(1.09709.0005)
Lieferant:
Merck
Hersteller-Artikelnummer::
1.09709.0005
Lokale Artikelnummer::
MERC1.09709.0005
Beschreibung:
Ethylmethylketon Bezugssubstanz für die Gaschromatographie, Supelco®
VE:
1 * 5 mL
Artikel-Nr:
(APOSOR301117-25G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR301117-25G
Lokale Artikelnummer::
APOSOR301117-25G
Beschreibung:
Ethyl-1-benzyl-3-oxopiperidine-4-carboxylate 95%
VE:
1 * 25 g
Lieferant:
Thermo Scientific
Beschreibung:
CAS No.: 4644-61-5
Artikel-Nr:
(BOSSBS-12143R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12143R-FITC
Lokale Artikelnummer::
BOSSBS-12143R-FITC
Beschreibung:
Major scaffold postsynaptic density protein which interacts with multiple proteins and complexes to orchestrate the dendritic spine and synapse formation, maturation and maintenance. Interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and HOMER, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction through the interaction with Arp2/3 and WAVE1 complex as well as the promotion of the F-actin clusters. By way of this control of actin dynamics, participates in the regulation of developing neurons growth cone motility and the NMDA receptor-signaling. Also modulates GRIA1 exocytosis and GRM5/MGLUR5 expression and signaling to control the AMPA and metabotropic glutamate receptor-mediated synaptic transmission and plasticity. May be required at an early stage of synapse formation and be inhibited by IGF1 to promote synapse maturation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9076R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9076R-FITC
Lokale Artikelnummer::
BOSSBS-9076R-FITC
Beschreibung:
Cyclin dependent kinase 5 (Cdk5) is a key regulator of cell cycle progression in neuronal differentiation that physically associates with and is activated by the neuron-specific protein p35. CDK5RAP1 (CDK5 regulatory subunit-associated protein 1) specifically inhibits Cdk5 activation by p35 through formation of a dimer that inhibits kinase activity. CDK5RAP2, also known as Centrosome-associated protein 215, is a 1893 amino acid centrosomal protein that regulates activity of CDK5 through complex formation with CDK5RAP1. Expressed in placenta, liver, pancreas, heart, skeletal muscle, lung, brain and kidney, CDK5RAP2 associates with centrosomes throughout the cell cycle. Mutations in the gene encoding CDK5RAP2 results in primary microencephaly autosomal recessive type 3, which is characterized by markedly reduced head size, brain weight and significant neurological deficits. There are four isoforms of CDK5RAP2 that are produced as a result of alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12143R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12143R-HRP
Lokale Artikelnummer::
BOSSBS-12143R-HRP
Beschreibung:
Major scaffold postsynaptic density protein which interacts with multiple proteins and complexes to orchestrate the dendritic spine and synapse formation, maturation and maintenance. Interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and HOMER, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction through the interaction with Arp2/3 and WAVE1 complex as well as the promotion of the F-actin clusters. By way of this control of actin dynamics, participates in the regulation of developing neurons growth cone motility and the NMDA receptor-signaling. Also modulates GRIA1 exocytosis and GRM5/MGLUR5 expression and signaling to control the AMPA and metabotropic glutamate receptor-mediated synaptic transmission and plasticity. May be required at an early stage of synapse formation and be inhibited by IGF1 to promote synapse maturation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13067R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13067R-A750
Lokale Artikelnummer::
BOSSBS-13067R-A750
Beschreibung:
Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF-binding sites are also constitutive promoter elements in many muscle-specific promoters. At the c-Fos SRE, formation of a ternary complex containing SRF and its accessory protein p62TCF appears to be important for signal transduction. Two related Ets domain proteins, Elk-1 and SRF accessory protein-1 (SAP-1), have DNA binding properties identical to that of p62TCF. Elk-1 and SAP-1 contain two homologous regions of which the two amino terminal regions, the Ets domain (box A) and the B box, mediate ternary complex formation with SRF. The third homologous region, the C box located toward the C-terminus of the proteins, contains conserved consensus phosphorylation sites for MAP kinases.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9076R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9076R-HRP
Lokale Artikelnummer::
BOSSBS-9076R-HRP
Beschreibung:
Cyclin dependent kinase 5 (Cdk5) is a key regulator of cell cycle progression in neuronal differentiation that physically associates with and is activated by the neuron-specific protein p35. CDK5RAP1 (CDK5 regulatory subunit-associated protein 1) specifically inhibits Cdk5 activation by p35 through formation of a dimer that inhibits kinase activity. CDK5RAP2, also known as Centrosome-associated protein 215, is a 1893 amino acid centrosomal protein that regulates activity of CDK5 through complex formation with CDK5RAP1. Expressed in placenta, liver, pancreas, heart, skeletal muscle, lung, brain and kidney, CDK5RAP2 associates with centrosomes throughout the cell cycle. Mutations in the gene encoding CDK5RAP2 results in primary microencephaly autosomal recessive type 3, which is characterized by markedly reduced head size, brain weight and significant neurological deficits. There are four isoforms of CDK5RAP2 that are produced as a result of alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9076R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9076R-CY5
Lokale Artikelnummer::
BOSSBS-9076R-CY5
Beschreibung:
Cyclin dependent kinase 5 (Cdk5) is a key regulator of cell cycle progression in neuronal differentiation that physically associates with and is activated by the neuron-specific protein p35. CDK5RAP1 (CDK5 regulatory subunit-associated protein 1) specifically inhibits Cdk5 activation by p35 through formation of a dimer that inhibits kinase activity. CDK5RAP2, also known as Centrosome-associated protein 215, is a 1893 amino acid centrosomal protein that regulates activity of CDK5 through complex formation with CDK5RAP1. Expressed in placenta, liver, pancreas, heart, skeletal muscle, lung, brain and kidney, CDK5RAP2 associates with centrosomes throughout the cell cycle. Mutations in the gene encoding CDK5RAP2 results in primary microencephaly autosomal recessive type 3, which is characterized by markedly reduced head size, brain weight and significant neurological deficits. There are four isoforms of CDK5RAP2 that are produced as a result of alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12043R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12043R-A350
Lokale Artikelnummer::
BOSSBS-12043R-A350
Beschreibung:
Members of the paired homeobox family play a role in regulating cell development and pattern formation during embryonic stages. UNCX (UNC homeobox), also known as UNCX4.1, is a 531 amino acid nuclear transcription factor involved in neurogenesis and somitogenesis. Containing one homeobox DNA-binding domain, UNCX belongs to the paired homeobox family and UNC4 subfamily. UNCX assists in the formation of connections between hypothalamic neurons and the pituitary, which is necessary for central neurons to deliver hormones into peripheral blood. UNCX also plays a role in maintaining differentiation of the axial skeleton and acts upstream of Pax-9. The gene encoding UNCX maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13067R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13067R-CY5
Lokale Artikelnummer::
BOSSBS-13067R-CY5
Beschreibung:
Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF-binding sites are also constitutive promoter elements in many muscle-specific promoters. At the c-Fos SRE, formation of a ternary complex containing SRF and its accessory protein p62TCF appears to be important for signal transduction. Two related Ets domain proteins, Elk-1 and SRF accessory protein-1 (SAP-1), have DNA binding properties identical to that of p62TCF. Elk-1 and SAP-1 contain two homologous regions of which the two amino terminal regions, the Ets domain (box A) and the B box, mediate ternary complex formation with SRF. The third homologous region, the C box located toward the C-terminus of the proteins, contains conserved consensus phosphorylation sites for MAP kinases.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13067R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13067R-A647
Lokale Artikelnummer::
BOSSBS-13067R-A647
Beschreibung:
Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF-binding sites are also constitutive promoter elements in many muscle-specific promoters. At the c-Fos SRE, formation of a ternary complex containing SRF and its accessory protein p62TCF appears to be important for signal transduction. Two related Ets domain proteins, Elk-1 and SRF accessory protein-1 (SAP-1), have DNA binding properties identical to that of p62TCF. Elk-1 and SAP-1 contain two homologous regions of which the two amino terminal regions, the Ets domain (box A) and the B box, mediate ternary complex formation with SRF. The third homologous region, the C box located toward the C-terminus of the proteins, contains conserved consensus phosphorylation sites for MAP kinases.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12143R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12143R-A680
Lokale Artikelnummer::
BOSSBS-12143R-A680
Beschreibung:
Major scaffold postsynaptic density protein which interacts with multiple proteins and complexes to orchestrate the dendritic spine and synapse formation, maturation and maintenance. Interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and HOMER, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction through the interaction with Arp2/3 and WAVE1 complex as well as the promotion of the F-actin clusters. By way of this control of actin dynamics, participates in the regulation of developing neurons growth cone motility and the NMDA receptor-Signalling. Also modulates GRIA1 exocytosis and GRM5/MGLUR5 expression and Signalling to control the AMPA and metabotropic glutamate receptor-mediated synaptic transmission and plasticity. May be required at an early stage of synapse formation and be inhibited by IGF1 to promote synapse maturation.
VE:
1 * 100 µl
Preis auf Anfrage
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