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4-Amino-5-chloro-2-methylpyridine
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4-Amino-5-chloro-2-methylpyridine
Artikel-Nr:
(BOSSBS-7984R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7984R-A680
Lokale Artikelnummer::
BOSSBS-7984R-A680
Beschreibung:
Carbonic anhydrases are a large family of zincmetalloenzymes that catalyze the reversible hydration of carbondioxide. They participate in a variety of biological processes,including respiration, calcification, acid-base balance, boneresorption, and the formation of aqueous humor, cerebrospinalfluid, saliva, and gastric acid. They show extensive diversity intissue distribution and in their subcellular localisation. Thecytosolic protein encoded by this gene is predominantly expressedin the salivary glands. Alternative splicing in the coding regionresults in multiple transcript variants encoding differentisoforms.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
Ethylacrylat 99.5% stabilisiert
Artikel-Nr:
(BOSSBS-4100R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4100R-CY5
Lokale Artikelnummer::
BOSSBS-4100R-CY5
Beschreibung:
Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally regulated apoptosis during neural tube formation. Required for a normal rate of cytochrome c release and caspase activation during apoptosis; this requirement may depend upon the cell type and the physiological apoptotic cues. Also required for mitochondrial fission during mitosis. Required for formation of endocytic vesicles. Proposed to regulate synaptic vesicle membrane dynamics through association with BCL2L1 isoform Bcl-X(L) which stimulates its GTPase activity in synaptic vesicles; the function may require its recruitment by MFF to clathrin-containing vesicles. Required for programmed necrosis execution. Isoform 1 and isoform 4 inhibit peroxisomal division when overexpressed.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4100R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4100R-CY7
Lokale Artikelnummer::
BOSSBS-4100R-CY7
Beschreibung:
Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally regulated apoptosis during neural tube formation. Required for a normal rate of cytochrome c release and caspase activation during apoptosis; this requirement may depend upon the cell type and the physiological apoptotic cues. Also required for mitochondrial fission during mitosis. Required for formation of endocytic vesicles. Proposed to regulate synaptic vesicle membrane dynamics through association with BCL2L1 isoform Bcl-X(L) which stimulates its GTPase activity in synaptic vesicles; the function may require its recruitment by MFF to clathrin-containing vesicles. Required for programmed necrosis execution. Isoform 1 and isoform 4 inhibit peroxisomal division when overexpressed.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3921R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3921R-CY5.5
Lokale Artikelnummer::
BOSSBS-3921R-CY5.5
Beschreibung:
The ADCY4 gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals. Alternative splicing results in transcript variants.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7696R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7696R-CY5.5
Lokale Artikelnummer::
BOSSBS-7696R-CY5.5
Beschreibung:
This gene encodes a protein that localizes to the nucleus and expression of this gene is induced in response to elevated levels of axin. The Wnt signalling pathway, which is negatively regulated by axin, is important in axis formation in early development and impaired regulation of this signalling pathway is often involved in tumors. A decreased level of expression of this gene in tumors compared to the level of expression in their corresponding normal tissues suggests that this gene product has a tumor suppressor function. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5986R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5986R-CY5.5
Lokale Artikelnummer::
BOSSBS-5986R-CY5.5
Beschreibung:
Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3921R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3921R-CY7
Lokale Artikelnummer::
BOSSBS-3921R-CY7
Beschreibung:
The ADCY4 gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals. Alternative splicing results in transcript variants.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7525R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7525R-A680
Lokale Artikelnummer::
BOSSBS-7525R-A680
Beschreibung:
Tenomodulin is related to chondromodulin-I, which is a cartilage-specific glycoprotein that functions to stimulate chondrocyte growth and to inhibit tube formation of endothelial cells. This protein is also an angiogenesis inhibitor. Genetic variation in this gene is associated with a risk for type 2 diabetes, central obesity and serum levels of systemic immune mediators in a body sise-dependent manner. This gene is also a candidate gene for age-related macular degeneration, though a direct link has yet to be demonstrated.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13475R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13475R-CY5
Lokale Artikelnummer::
BOSSBS-13475R-CY5
Beschreibung:
Glucosamine 6-phosphate N-acetyltransferase (GNA1), also designated phosphoglucosamine transacetylase or phosphoglucosamine acetylase, belongs to the GNA1 subfamily of the larger acetyltransferase family of proteins. GNA1, a peripheral membrane protein containing one N-acetyltransferase domain, is expressed in the colon and maps to cytoband 14q22.1. The protein localizes to the Golgi apparatus and the endosome. It is important for UDP-GlcNAc biosynthesis pathway. GNA1 catalyzes the synthesis of GlcNAc6P from AcCoA and GlcN6P, a step in the UDP-GlcNAc6P formation pathway.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3921R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3921R-A488
Lokale Artikelnummer::
BOSSBS-3921R-A488
Beschreibung:
The ADCY4 gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals. Alternative splicing results in transcript variants.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
o-Ethyltoluol ≥98%
Lieferant:
Thermo Scientific
Beschreibung:
Ethylvinylether 99% stabilisiert
Artikel-Nr:
(BOSSBS-1091R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1091R-A647
Lokale Artikelnummer::
BOSSBS-1091R-A647
Beschreibung:
Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11028R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11028R-A750
Lokale Artikelnummer::
BOSSBS-11028R-A750
Beschreibung:
Facilitates tyrosination of alpha-tubulin in neuronal microtubules (By similarity). Phosphorylated MAP1B may play a role in the cytoskeletal changes that accompany neurite extension. Possibly MAP1B binds to at least two tubulin subunits in the polymer, and this bridging of subunits might be involved in nucleating microtubule polymerization and in stabilizing microtubules. Acts as a positive cofactor in DAPK1-mediated autophagic vesicle formation and membrane blebbing.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9790R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9790R-A750
Lokale Artikelnummer::
BOSSBS-9790R-A750
Beschreibung:
Can cross-link actin filaments into both network and bundle structures (By similarity). May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton. Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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