Ethyl-2-naphthoyl+formate
Artikel-Nr:
(APOSOR3366-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR3366-1G
Lokale Artikelnummer::
APOSOR3366-1G
Beschreibung:
Ethylimidazo[1,2-a]pyridin-7-carboxylat
VE:
1 * 1 g
Artikel-Nr:
(BOSSBS-5895R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5895R-FITC
Lokale Artikelnummer::
BOSSBS-5895R-FITC
Beschreibung:
WASP (for Wiskott-Aldrich syndrome protein) and N-WASP are downstream effectors of Cdc42 that are implicated in Actin polymerization and cytoskeletal organization. The WASP family also includes VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein), which accumulate at focal adhesions and are also involved in the regulation of the Actin cytoskeleton. The WAVE proteins are related to the WASP family proteins and are likewise involved in mediating Actin reorganization downstream of the Rho family of small GTPases. The protein homologs WAVE1 and WAVE2 regulate membrane ruffling by inducing the formation of Actin filament clusters in response to GTP binding and by activating Rac. They mediate Actin polymerization by cooperating with the Arp2/3 complex, thereby promoting the formation of Actin filaments. WAVE1, which is also designated SCAR (suppressor of cAR), is expressed primarily in the brain, while WAVE2 is widely expressed, with the expression highest in peripheral blood leukocytes. WAVE3 forms a multiprotein complex that links receptor kinases with Actin and plays a role in the transduction of signals involving changes in cell shape, function or motility.
VE:
1 * 100 µl
Artikel-Nr:
(APOSOR350169-5G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR350169-5G
Lokale Artikelnummer::
APOSOR350169-5G
Beschreibung:
Mecarbinate
VE:
1 * 5 g
Artikel-Nr:
(APOSOR346636-10G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR346636-10G
Lokale Artikelnummer::
APOSOR346636-10G
Beschreibung:
3-Ethylacetylaceton 95+%
VE:
1 * 10 g
Lieferant:
Cayman Chemical
Beschreibung:
Rivastigmine is an irreversible inhibitor of acetylcholinesterase (IC<sub>50</sub>=4,15 µm) and butyrylcholinesterase (IC<sub>50</sub>=37 nM).
Artikel-Nr:
(BOSSBS-3050R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3050R-A350
Lokale Artikelnummer::
BOSSBS-3050R-A350
Beschreibung:
Mitotic serine/threonine kinases that contributes to the regulation of cell cycle progression. Associates with the centrosome and the spindle microtubules during mitosis and plays a critical role in various mitotic events including the establishment of mitotic spindle, centrosome duplication, centrosome separation as well as maturation, chromosomal alignment, spindle assembly checkpoint, and cytokinesis. Required for initial activation of CDK1 at centrosomes. Phosphorylates numerous target proteins, including ARHGEF2, BORA, BRCA1, CDC25B, DLGP5, HDAC6, KIF2A, LATS2, NDEL1, PARD3, PPP1R2, PLK1, RASSF1, TACC3, p53/TP53 and TPX2. Regulates KIF2A tubulin depolymerase activity. Required for normal axon formation. Plays a role in microtubule remodeling during neurite extension. Important for microtubule formation and/or stabilization. Also acts as a key regulatory component of the p53/TP53 pathway, and particularly the checkpoint-response pathways critical for oncogenic transformation of cells, by phosphorylating and stabilizing p53/TP53. Phosphorylates its own inhibitors, the protein phosphatase type 1 (PP1) isoforms, to inhibit their activity. Necessary for proper cilia disassembly prior to mitosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3050R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3050R-CY7
Lokale Artikelnummer::
BOSSBS-3050R-CY7
Beschreibung:
Mitotic serine/threonine kinases that contributes to the regulation of cell cycle progression. Associates with the centrosome and the spindle microtubules during mitosis and plays a critical role in various mitotic events including the establishment of mitotic spindle, centrosome duplication, centrosome separation as well as maturation, chromosomal alignment, spindle assembly checkpoint, and cytokinesis. Required for initial activation of CDK1 at centrosomes. Phosphorylates numerous target proteins, including ARHGEF2, BORA, BRCA1, CDC25B, DLGP5, HDAC6, KIF2A, LATS2, NDEL1, PARD3, PPP1R2, PLK1, RASSF1, TACC3, p53/TP53 and TPX2. Regulates KIF2A tubulin depolymerase activity. Required for normal axon formation. Plays a role in microtubule remodeling during neurite extension. Important for microtubule formation and/or stabilization. Also acts as a key regulatory component of the p53/TP53 pathway, and particularly the checkpoint-response pathways critical for oncogenic transformation of cells, by phosphorylating and stabilizing p53/TP53. Phosphorylates its own inhibitors, the protein phosphatase type 1 (PP1) isoforms, to inhibit their activity. Necessary for proper cilia disassembly prior to mitosis.
VE:
1 * 100 µl
Artikel-Nr:
(734-1079)
Lieferant:
Corning
Hersteller-Artikelnummer::
354803
Lokale Artikelnummer::
BDAA354803
Beschreibung:
This system is packaged with ready-to-use Falcon® Companion Plates.
VE:
1 * 1 ST
Artikel-Nr:
(APOSOR5607-5G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR5607-5G
Lokale Artikelnummer::
APOSOR5607-5G
Beschreibung:
Ethylthiazol-5-carboxylat 98%
VE:
1 * 5 g
Artikel-Nr:
(BOSSBS-11640R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11640R-A680
Lokale Artikelnummer::
BOSSBS-11640R-A680
Beschreibung:
Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyses the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex. Probably present in a minority of gamma-secretase complexes compared to APH1A.
VE:
1 * 100 µl
Lieferant:
Merck
Beschreibung:
Highest purity solvents for UHPLC-MS analysis.
Artikel-Nr:
(BOSSBS-5019R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5019R-A488
Lokale Artikelnummer::
BOSSBS-5019R-A488
Beschreibung:
This gene encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in this gene are associated with 3-ketothiolase deficiency, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone. [provided by RefSeq, Feb 2009].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4282R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4282R-A488
Lokale Artikelnummer::
BOSSBS-4282R-A488
Beschreibung:
GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5899R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5899R-A647
Lokale Artikelnummer::
BOSSBS-5899R-A647
Beschreibung:
Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4282R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4282R-A750
Lokale Artikelnummer::
BOSSBS-4282R-A750
Beschreibung:
GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules.
VE:
1 * 100 µl
Preis auf Anfrage
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