Ethyl-2-naphthoyl+formate
Artikel-Nr:
(ENZOADISAB300J)
Lieferant:
ENZO LIFE SCIENCES
Hersteller-Artikelnummer::
ADISAB300J
Lokale Artikelnummer::
ENZOADISAB300J
Beschreibung:
Immunoglobulin G (IgG) is an immunoglobulin monomer consisting of two (gamma) heavy chains and two light chains. Each IgG molecule contains two antigen binding domains and a single effector (Fc) domain. Assay designs offers isotyping kits and antibodies in a variety of formats for the detection of human, mouse, rabbit, rat, sheep, and goat IgG.
VE:
1 * 1 mL
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
A potent antitumor antibiotic.
Lieferant:
Merck
Beschreibung:
Bio-Based Ethanol
Instead of synthetic ethanol, we use bioethanol produced from grain or sugar cane. High quality, affordability, and ready availability make our bioethanol an obvious choice for a sustainable future.
Artikel-Nr:
(PRSI96-089)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-089
Lokale Artikelnummer::
PRSI96-089
Beschreibung:
CD40 is also known as TNFRSF5, Bp50, CDW40, MGC9013, TNFRSF5 and p50, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins, and plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects. CD40 contains 4 cysteine-rich repeats in the extracellular domain, and is expressed in B cells, dendritic cells, macrophages, endothelial cells, and several tumor cell lines. The extracellular domain has the cysteinerich repeat regions, which are characteristic for many of the receptors of the TNF superfamily. Interaction of CD40 with its ligand, CD40L, leads to aggregation of CD40 molecules,which in turn interact with cytoplasmic components to initiate signaling pathways. Early studies on the CD40-CD40L system revealed its role in humoral immunity. Defects in CD40 result in hyper-IgM immunodeficiency type 3 (HIGM3), an autosomal recessive disorder characterized by an inability of B cells to undergo isotype switching, as well as an inability to mount an antibody-specific immune response, and a lack of germinal center formation.
VE:
1 * 0,1 mg
New Product
Lieferant:
Thermo Scientific
Beschreibung:
Coomassie® Brillantblau R 250, rein
Lieferant:
Avantor
Beschreibung:
Diethylether stabilisiert, BAKER ANALYZED® ACS, J.T.Baker®
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2-Amino-3,3,3-trifluoropropionic acid ethylester hydrochloride 96%
Artikel-Nr:
(BLDPBD20623-25G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD20623-25G
Lokale Artikelnummer::
BLDPBD20623-25G
Beschreibung:
Nitrendipine 98%
VE:
1 * 25 g
Artikel-Nr:
(BNUM0424-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM0424-50
Lokale Artikelnummer::
BTIUBNUM0424-50
Beschreibung:
This MAb recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.
VE:
1 * 50 µl
Artikel-Nr:
(APOSOR1575-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR1575-1G
Lokale Artikelnummer::
APOSOR1575-1G
Beschreibung:
N-Methyldopamine hydrochloride 98%
VE:
1 * 1 g
Artikel-Nr:
(BOSSBS-11466R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11466R-A750
Lokale Artikelnummer::
BOSSBS-11466R-A750
Beschreibung:
Cell surface protein involved in cell-cell-interactions, exocytosis of secretory granules and regulation of signal transmission. Function is isoform-specific. Alpha-type isoforms have a long N-terminus with six laminin G-like domains and play an important role in synaptic signal transmission. Alpha-type isoforms play a role in the regulation of calcium channel activity and Ca²⁺-triggered neurotransmitter release at synapses and at neuromuscular junctions. They play an important role in Ca²⁺-triggered exocytosis of secretory granules in pituitary gland. They may effect their functions at synapses and in endocrine cells via their interactions with proteins from the exocytotic machinery. Likewise, alpha-type isoforms play a role in regulating the activity of postsynaptic NMDA receptors, a subtype of glutamate-gated ion channels. Both alpha-type and beta-type isoforms may play a role in the formation or maintenance of synaptic junctions via their calcium-dependent interactions (via the extracellular domains) with neuroligin family members, CBLN1 or CBLN2. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. Alpha-type isoforms were first identified as receptors for alpha-latrotoxin from spider venom (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11466R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11466R-HRP
Lokale Artikelnummer::
BOSSBS-11466R-HRP
Beschreibung:
Cell surface protein involved in cell-cell-interactions, exocytosis of secretory granules and regulation of signal transmission. Function is isoform-specific. Alpha-type isoforms have a long N-terminus with six laminin G-like domains and play an important role in synaptic signal transmission. Alpha-type isoforms play a role in the regulation of calcium channel activity and Ca(2+)-triggered neurotransmitter release at synapses and at neuromuscular junctions. They play an important role in Ca(2+)-triggered exocytosis of secretory granules in pituitary gland. They may effect their functions at synapses and in endocrine cells via their interactions with proteins from the exocytotic machinery. Likewise, alpha-type isoforms play a role in regulating the activity of postsynaptic NMDA receptors, a subtype of glutamate-gated ion channels. Both alpha-type and beta-type isoforms may play a role in the formation or maintenance of synaptic junctions via their calcium-dependent interactions (via the extracellular domains) with neuroligin family members, CBLN1 or CBLN2. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. Alpha-type isoforms were first identified as receptors for alpha-latrotoxin from spider venom (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4938R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4938R-A350
Lokale Artikelnummer::
BOSSBS-4938R-A350
Beschreibung:
Chemoattractant active on T-lymphocytes, monocytes, but not neutrophils. Activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. Also binds to atypical chemokine receptor ACKR3, which activates the beta-arrestin pathway and acts as a scavenger receptor for SDF-1. SDF-1-beta(3-72) and SDF-1-alpha(3-67) show a reduced chemotactic activity. Binding to cell surface proteoglycans seems to inhibit formation of SDF-1-alpha(3-67) and thus to preserve activity on local sites. Acts as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the LYN kinase. Stimulates migration of monocytes and T-lymphocytes through its receptors, CXCR4 and ACKR3, and decreases monocyte adherence to surfaces coated with ICAM-1, a ligand for beta-2 integrins. SDF1A/CXCR4 signaling axis inhibits beta-2 integrin LFA-1 mediated adhesion of monocytes to ICAM-1 through LYN kinase. Inhibits CXCR4-mediated infection by T-cell line-adapted HIV-1. Plays a protective role after myocardial infarction. Induces down-regulation and internalization of ACKR3 expressed in various cells. Has several critical functions during embryonic development; required for B-cell lymphopoiesis, myelopoiesis in bone marrow and heart ventricular septum formation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11466R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11466R-A555
Lokale Artikelnummer::
BOSSBS-11466R-A555
Beschreibung:
Cell surface protein involved in cell-cell-interactions, exocytosis of secretory granules and regulation of signal transmission. Function is isoform-specific. Alpha-type isoforms have a long N-terminus with six laminin G-like domains and play an important role in synaptic signal transmission. Alpha-type isoforms play a role in the regulation of calcium channel activity and Ca(2+)-triggered neurotransmitter release at synapses and at neuromuscular junctions. They play an important role in Ca(2+)-triggered exocytosis of secretory granules in pituitary gland. They may effect their functions at synapses and in endocrine cells via their interactions with proteins from the exocytotic machinery. Likewise, alpha-type isoforms play a role in regulating the activity of postsynaptic NMDA receptors, a subtype of glutamate-gated ion channels. Both alpha-type and beta-type isoforms may play a role in the formation or maintenance of synaptic junctions via their calcium-dependent interactions (via the extracellular domains) with neuroligin family members, CBLN1 or CBLN2. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. Alpha-type isoforms were first identified as receptors for alpha-latrotoxin from spider venom (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4938R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4938R-CY7
Lokale Artikelnummer::
BOSSBS-4938R-CY7
Beschreibung:
Chemoattractant active on T-lymphocytes, monocytes, but not neutrophils. Activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. Also binds to atypical chemokine receptor ACKR3, which activates the beta-arrestin pathway and acts as a scavenger receptor for SDF-1. SDF-1-beta(3-72) and SDF-1-alpha(3-67) show a reduced chemotactic activity. Binding to cell surface proteoglycans seems to inhibit formation of SDF-1-alpha(3-67) and thus to preserve activity on local sites. Acts as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the LYN kinase. Stimulates migration of monocytes and T-lymphocytes through its receptors, CXCR4 and ACKR3, and decreases monocyte adherence to surfaces coated with ICAM-1, a ligand for beta-2 integrins. SDF1A/CXCR4 signaling axis inhibits beta-2 integrin LFA-1 mediated adhesion of monocytes to ICAM-1 through LYN kinase. Inhibits CXCR4-mediated infection by T-cell line-adapted HIV-1. Plays a protective role after myocardial infarction. Induces down-regulation and internalization of ACKR3 expressed in various cells. Has several critical functions during embryonic development; required for B-cell lymphopoiesis, myelopoiesis in bone marrow and heart ventricular septum formation.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
Applications: As a solvent soluble laser dye
Preis auf Anfrage
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