Ethyl-2-naphthoyl+formate
Artikel-Nr:
(BOSSBS-2700R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2700R-FITC
Lokale Artikelnummer::
BOSSBS-2700R-FITC
Beschreibung:
Cytokeratin 10 is a heterotetramer of two type I and two type II keratins. Cytokeratin 10 is generally associated with keratin 1. It is seen in all suprabasal cell layers including stratum corneum. A number of alleles are known that mainly differ in the Gly-rich region (positions 490-560). Defects in cytokeratin 10 are a cause of epidermolytic hyperkeratosis (EHK), also known as bullous congenital ichthyosiform erythroderma (BCIE) or bullous erythroderma ichthyosiformis congenita of Brocq. EHK is an hereditary skin disorder characterized by blistering and a marked thickening of the stratum corneum. At birth, affected individuals usually present with redness, blisters and superficial erosions due to cytolysis. Within a few weeks, the erythroderma and blister formation diminish and hyperkeratoses develop. Transmission is autosomal dominant, but most cases are sporadic. Defects in cytokeratin 10 are also a cause of annular epidermolytic ichthyosis (AEI), also known as cyclic ichthyosis with epidermolytic hyperkeratosis. AEI resembles clinical and histologic features of both epidermolytic hyperkeratosis and ichthyosis bullosa of Siemens.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12311R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12311R-A488
Lokale Artikelnummer::
BOSSBS-12311R-A488
Beschreibung:
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The primary function of these motifs is to provide a versatile structural framework to mediate the formation of protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in genes encoding LRR-containing proteins. LRRC23 (leucine-rich repeat-containing protein 23), also known as leucine-rich protein B7, is a 343 amino acid protein that contains eight LRR (leucine-rich) repeasts and one LRRCT domain. LRRC23 exists as two alternatively spliced isoforms and is encoded by a gene mapping to chromosome 12.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11771R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11771R-HRP
Lokale Artikelnummer::
BOSSBS-11771R-HRP
Beschreibung:
SCA11 is a 1,244 amino acid protein that belongs to the protein kinase superfamily and the CK1 Ser/Thr protein kinase family. The SCA11 gene, comprising of 16 exons, produces a 5.6-kb transcript in which the longest open reading frame is 3,732 nucleotides. Defects in the SCA11 protein are the cause of the disorder spinocerebellar ataxia type 11 (SCA11). Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. The SCA11 disorder is an autosomal dominant cerebellar ataxia (ADCA). It is a relatively benign, late-onset, slowly progressive neurologic disorder. The SCA11 protein has also been implicated in Alzheimer disease and in tangle formation. Existing as three alternatively spliced isoforms, the SCA11 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 15q15.2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12273R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12273R-HRP
Lokale Artikelnummer::
BOSSBS-12273R-HRP
Beschreibung:
Early ovarian folliculogenesis is characterized by the breakdown of germ cell clusters and formation of primordial follicles. The cessation of ovarian function under the age of 40 years results in premature ovarian failure (POF) and is accompanied by amenorrhea, hypoestrogenism and elevated serum gonadotropin concentrations. 1% of all women are affected by POF, and mutations in a few genes, including inhibin? fsh receptor and the LH/choriogonadotropin receptor have been linked to POF. In addition, several germ cell specific genes and downstream transcription factors are thought to play and important role in human oogenesis. NOBOX (newborn ovary homeobox gene), an ooctye-specific homeobox gene, is a critical protein involved in early folliculogenesis. Missense mutations have been shown to cause nonsyndromic ovarian failure by disrupting the NOBOX proteins ability to bind to NOBOX DNA-binding element (NBE), and thereby inhibiting its regulation of Pou5f1 and GDF-9. NOBOX expression in the ovary is oocyte specific, but it shows expression in adult testis and pancreas as well.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4605R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4605R-A488
Lokale Artikelnummer::
BOSSBS-4605R-A488
Beschreibung:
Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues in association with MMP14. PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels. Isoform 2: Mediates the proteolysis of CHUK/IKKA and initiates a primary innate immune response by inducing mitochondrial-nuclear stress signaling with activation of the pro-inflammatory NF-kappaB, NFAT and IRF transcriptional pathways.
VE:
1 * 100 µl
Artikel-Nr:
(SIAL565903-5G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
565903-5G
Lokale Artikelnummer::
SIAL565903-5G
Beschreibung:
Ethyl α-chlorphenylacetat, Sigma-Aldrich®
VE:
1 * 5 g
Lieferant:
Thermo Scientific
Beschreibung:
1-Ethyl-2-iodbenzol
Lieferant:
Sigma-Aldrich
Beschreibung:
Benzocain (Ethyl-4-aminobenzoat), Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
Ethyl-3-hydroxybenzoat, Sigma-Aldrich®
Artikel-Nr:
(FLUO035925-5G)
Lieferant:
FLUOROCHEM
Hersteller-Artikelnummer::
035925-5G
Lokale Artikelnummer::
FLUO035925-5G
Beschreibung:
Ethyl(4-fluorbenzoyl)formiat
VE:
1 * 5 g
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Lieferant:
Sigma-Aldrich
Beschreibung:
1-Ethyl-3-methylimidazoliumdiethylphosphat, Sigma-Aldrich®
Lieferant:
Thermo Scientific
Beschreibung:
Tetraethylenglycoldimethylether 99%
Artikel-Nr:
(SIALE24859-5G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
E24859-5G
Lokale Artikelnummer::
SIALE24859-5G
Beschreibung:
Ethyl-3,4-dihydroxybenzoat, Sigma-Aldrich®
VE:
1 * 5 g
Artikel-Nr:
(FLUO019299-1G)
Lieferant:
FLUOROCHEM
Hersteller-Artikelnummer::
019299-1G
Lokale Artikelnummer::
FLUO019299-1G
Beschreibung:
5'-Ethyl-2'-methoxy-3'-nitroacetophenon
VE:
1 * 1 g
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Lieferant:
Sigma-Aldrich
Beschreibung:
(Ethyl)triphenylphosphoniumbromid, Sigma-Aldrich®
Lieferant:
Agilent
Beschreibung:
It prevents the formation of spurious peaks within the detector due to solvent outgassing at the low-pressure end of the chromatograph.
Preis auf Anfrage
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