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Ethyl-2-naphthoyl+formate
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Ethyl-2-naphthoyl+formate
Artikel-Nr:
(BOSSBS-0771R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0771R-A750
Lokale Artikelnummer::
BOSSBS-0771R-A750
Beschreibung:
Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca2+ transport in skeletal muscle. In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner. This structural function is required for correct targeting of CaMK2A, which acts downstream of NMDAR to promote dendritic spine and synapse formation and maintain synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning. In developing hippocampal neurons, promotes arborization of the dendritic tree and in mature neurons, promotes dendritic remodelling. Participates in the modulation of skeletal muscle function in response to exercise. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca2+ transport and in fast-twitch muscle participates in the control of Ca2+ release from the SR through phosphorylation of triadin, a ryanodine receptor-coupling factor, and phospholamban (PLN/PLB), an endogenous inhibitor of SERCA2A/ATP2A2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3050R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3050R-CY5
Lokale Artikelnummer::
BOSSBS-3050R-CY5
Beschreibung:
Mitotic serine/threonine kinases that contributes to the regulation of cell cycle progression. Associates with the centrosome and the spindle microtubules during mitosis and plays a critical role in various mitotic events including the establishment of mitotic spindle, centrosome duplication, centrosome separation as well as maturation, chromosomal alignment, spindle assembly checkpoint, and cytokinesis. Required for initial activation of CDK1 at centrosomes. Phosphorylates numerous target proteins, including ARHGEF2, BORA, BRCA1, CDC25B, DLGP5, HDAC6, KIF2A, LATS2, NDEL1, PARD3, PPP1R2, PLK1, RASSF1, TACC3, p53/TP53 and TPX2. Regulates KIF2A tubulin depolymerase activity. Required for normal axon formation. Plays a role in microtubule remodeling during neurite extension. Important for microtubule formation and/or stabilization. Also acts as a key regulatory component of the p53/TP53 pathway, and particularly the checkpoint-response pathways critical for oncogenic transformation of cells, by phosphorylating and stabilizing p53/TP53. Phosphorylates its own inhibitors, the protein phosphatase type 1 (PP1) isoforms, to inhibit their activity. Necessary for proper cilia disassembly prior to mitosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3050R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3050R-A680
Lokale Artikelnummer::
BOSSBS-3050R-A680
Beschreibung:
Mitotic serine/threonine kinases that contributes to the regulation of cell cycle progression. Associates with the centrosome and the spindle microtubules during mitosis and plays a critical role in various mitotic events including the establishment of mitotic spindle, centrosome duplication, centrosome separation as well as maturation, chromosomal alignment, spindle assembly checkpoint, and cytokinesis. Required for initial activation of CDK1 at centrosomes. Phosphorylates numerous target proteins, including ARHGEF2, BORA, BRCA1, CDC25B, DLGP5, HDAC6, KIF2A, LATS2, NDEL1, PARD3, PPP1R2, PLK1, RASSF1, TACC3, p53/TP53 and TPX2. Regulates KIF2A tubulin depolymerase activity. Required for normal axon formation. Plays a role in microtubule remodeling during neurite extension. Important for microtubule formation and/or stabilisation. Also acts as a key regulatory component of the p53/TP53 pathway, and particularly the checkpoint-response pathways critical for oncogenic transformation of cells, by phosphorylating and stabilising p53/TP53. Phosphorylates its own inhibitors, the protein phosphatase type 1 (PP1) isoforms, to inhibit their activity. Necessary for proper cilia disassembly prior to mitosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4259R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4259R-HRP
Lokale Artikelnummer::
BOSSBS-4259R-HRP
Beschreibung:
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7949R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7949R-HRP
Lokale Artikelnummer::
BOSSBS-7949R-HRP
Beschreibung:
Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5579R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5579R-A647
Lokale Artikelnummer::
BOSSBS-5579R-A647
Beschreibung:
Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4054R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4054R-HRP
Lokale Artikelnummer::
BOSSBS-4054R-HRP
Beschreibung:
S adenosylmethionine synthetase catalyzes the formation of S adenosylmethionine from methionine and ATP. In mammalian tissues, there are three distinct forms of AdoMet synthases designated as alpha, beta, and gamma. Alpha and beta are expressed only in adult liver, while gamma is widely distributed in extrahepatic tissues.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5579R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5579R-HRP
Lokale Artikelnummer::
BOSSBS-5579R-HRP
Beschreibung:
Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4159R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4159R-A555
Lokale Artikelnummer::
BOSSBS-4159R-A555
Beschreibung:
Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1944R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1944R-FITC
Lokale Artikelnummer::
BOSSBS-1944R-FITC
Beschreibung:
The WRCH1 protein is a member of the Rho family of GTPases. This protein can activate PAK1 and JNK1, and can induce filopodium formation and stress fiber dissolution. It may also mediate the effects of WNT1 signaling in the regulation of cell morphology, cytoskeletal organization, and cell proliferation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5579R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5579R-FITC
Lokale Artikelnummer::
BOSSBS-5579R-FITC
Beschreibung:
Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes.
VE:
1 * 100 µl
Artikel-Nr:
(NALG6219-0068)
Lieferant:
Thermo Fisher Scientific
Hersteller-Artikelnummer::
6219-0068
Lokale Artikelnummer::
NALG6219-0068
Beschreibung:
LDPE. Moulded in one piece. Non wetting material, tapered tip, and bellows-type bulb provide excellent drop formation.
VE:
1 * 100 ST
Artikel-Nr:
(BOSSBS-11317R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11317R-HRP
Lokale Artikelnummer::
BOSSBS-11317R-HRP
Beschreibung:
Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3633R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3633R-A488
Lokale Artikelnummer::
BOSSBS-3633R-A488
Beschreibung:
Actin-associated protein that may play a role in modulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. Seems to be essential for the formation of spine apparatuses in spines of telencephalic neurons, which is involved in synaptic plasticity (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5674R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5674R-FITC
Lokale Artikelnummer::
BOSSBS-5674R-FITC
Beschreibung:
The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5674R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5674R-A555
Lokale Artikelnummer::
BOSSBS-5674R-A555
Beschreibung:
The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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