1-Methylimidazol-5-carbonsäure
Lieferant:
Sigma-Aldrich
Beschreibung:
Hexaamminruthenium(III)chlorid, Sigma-Aldrich®
Artikel-Nr:
(HACH1422249)
Lieferant:
Hach
Hersteller-Artikelnummer::
1422249
Lokale Artikelnummer::
HACH1422249
Beschreibung:
Cobalt chloride solution for spectrophotometer linearisation.
VE:
1 * 500 mL
Artikel-Nr:
(BOSSBS-2927R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2927R-FITC
Lokale Artikelnummer::
BOSSBS-2927R-FITC
Beschreibung:
OXSR1 is a serine/threonine kinase which regulates downstream kinases in response to environmental stress such as osmotic stresses, notably sorbitol and, to a lesser extent, NaCl. OXSR1 phosphorylated thr84 within the N-terminal regulatory domain of PAK1. Replacement of thr84 with gln reduced activation of PAK1 by an active form of the small G protein CDC42, suggesting that phosphorylation by OXSR1 modulates the G protein sensitivity of PAK. OXSR1 interacts with chloride channel proteins SLC12A6 isoform 2, SLC12A1 and SLC12A2 but not with SLC12A4 and SLC12A7, possibly establishing sensor/signaling modules that initiate the cellular response to environmental stress. Binds to and phosphorylates RELL1, RELL2 AND RELT. OXSR1 may have a role in regulating the actin cytoskeleton.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2927R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2927R-CY5
Lokale Artikelnummer::
BOSSBS-2927R-CY5
Beschreibung:
OXSR1 is a serine/threonine kinase which regulates downstream kinases in response to environmental stress such as osmotic stresses, notably sorbitol and, to a lesser extent, NaCl. OXSR1 phosphorylated thr84 within the N-terminal regulatory domain of PAK1. Replacement of thr84 with gln reduced activation of PAK1 by an active form of the small G protein CDC42, suggesting that phosphorylation by OXSR1 modulates the G protein sensitivity of PAK. OXSR1 interacts with chloride channel proteins SLC12A6 isoform 2, SLC12A1 and SLC12A2 but not with SLC12A4 and SLC12A7, possibly establishing sensor/signaling modules that initiate the cellular response to environmental stress. Binds to and phosphorylates RELL1, RELL2 AND RELT. OXSR1 may have a role in regulating the actin cytoskeleton.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11661R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11661R-A750
Lokale Artikelnummer::
BOSSBS-11661R-A750
Beschreibung:
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 (PubMed:12954870). Associated with KCNC4/Kv3.4 is proposed to form the subthreshold voltage-gated potassium channel in skeletal muscle and to establish the resting membrane potential (RMP) in muscle cells. Associated with KCNQ1/KCLQT1 may form the intestinal cAMP-stimulated potassium channel involved in chloride secretion that produces a current with nearly instantaneous activation with a linear current-voltage relationship.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2927R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2927R-A350
Lokale Artikelnummer::
BOSSBS-2927R-A350
Beschreibung:
OXSR1 is a serine/threonine kinase which regulates downstream kinases in response to environmental stress such as osmotic stresses, notably sorbitol and, to a lesser extent, NaCl. OXSR1 phosphorylated thr84 within the N-terminal regulatory domain of PAK1. Replacement of thr84 with gln reduced activation of PAK1 by an active form of the small G protein CDC42, suggesting that phosphorylation by OXSR1 modulates the G protein sensitivity of PAK. OXSR1 interacts with chloride channel proteins SLC12A6 isoform 2, SLC12A1 and SLC12A2 but not with SLC12A4 and SLC12A7, possibly establishing sensor/signaling modules that initiate the cellular response to environmental stress. Binds to and phosphorylates RELL1, RELL2 AND RELT. OXSR1 may have a role in regulating the actin cytoskeleton.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2672R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2672R-CY7
Lokale Artikelnummer::
BOSSBS-2672R-CY7
Beschreibung:
The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
3-(2,6-Dichlorphenyl)-5-methyl-4-isoxazolcarbonsäurechlorid
Artikel-Nr:
(BOSSBS-7098R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7098R-FITC
Lokale Artikelnummer::
BOSSBS-7098R-FITC
Beschreibung:
Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Promotes cell-surface expression of HRH3. Has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis. Could also promote endothelial cell proliferation and regulate endothelial morphogenesis.Tissue specificity: Detected in epithelial cells from colon, esophagus and kidney (at protein level). Expression is prominent in heart, kidney, placenta and skeletal muscle.
VE:
1 * 100 µl
Artikel-Nr:
(PROOALK-LCL-30-5)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
ALK-LCL-30-5
Lokale Artikelnummer::
PROOALK-LCL-30-5
Beschreibung:
2 M Lithium chloride electrolyte, electrode filling solution
VE:
1 * 150 mL
Artikel-Nr:
(REST30089)
Lieferant:
Restek
Hersteller-Artikelnummer::
30089
Lokale Artikelnummer::
REST30089
Beschreibung:
Organic Standard, Vinyl chloride, 1 ml/ampoule
VE:
1 * 1 mL
Artikel-Nr:
(BOSSBS-2927R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2927R-HRP
Lokale Artikelnummer::
BOSSBS-2927R-HRP
Beschreibung:
OXSR1 is a serine/threonine kinase which regulates downstream kinases in response to environmental stress such as osmotic stresses, notably sorbitol and, to a lesser extent, NaCl. OXSR1 phosphorylated thr84 within the N-terminal regulatory domain of PAK1. Replacement of thr84 with gln reduced activation of PAK1 by an active form of the small G protein CDC42, suggesting that phosphorylation by OXSR1 modulates the G protein sensitivity of PAK. OXSR1 interacts with chloride channel proteins SLC12A6 isoform 2, SLC12A1 and SLC12A2 but not with SLC12A4 and SLC12A7, possibly establishing sensor/signaling modules that initiate the cellular response to environmental stress. Binds to and phosphorylates RELL1, RELL2 AND RELT. OXSR1 may have a role in regulating the actin cytoskeleton.
VE:
1 * 100 µl
Lieferant:
Serva
Beschreibung:
2-(4-Iodphenyl)-3-(4-nitrophenyl)-5-phenyltetrazoliumchlorid
Artikel-Nr:
(BOSSBS-11040R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11040R
Lokale Artikelnummer::
BOSSBS-11040R
Beschreibung:
Best vitelliform macular dystrophy, known as Best disease, is an early-onset autosomal dominant condition in which accumulation of lipofuscin-like material within and beneath the RPE leads to progressive loss of central vision. Best disease is frequently a reflection of mutations in the Bestrophin gene, which encodes a protein containing four putative transmembrane domains and localizes to the basolateral plasma membrane of RPE cells. Human Bestrophin forms oligomeric chloride channels that are sensitive to intracellular calcium. Missense mutations at the Bestrophin locus reduces or abolishes Bestrophin protein mediated membrane current. Bestrophin Bestrophin 2,Bestrophin 3, and Bestrophin 4 are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels.
VE:
1 * 100 µl
Lieferant:
Sigma-Aldrich
Beschreibung:
Tetrahydrofuran -trichlorvanadium (1:1), Sigma-Aldrich®
Lieferant:
Thermo Scientific
Beschreibung:
Zirkonylchlorid Octahydrat 98%
Preis auf Anfrage
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