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Horizontal+Gel+Electrophoresis+Systems
Artikel-Nr:
(BOSSBS-1764R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1764R-A488
Lokale Artikelnummer::
BOSSBS-1764R-A488
Beschreibung:
Receptor tyrosine kinase which binds membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Highly promiscuous, it has the unique property among Eph receptors to bind and to be physiologically activated by both GPI-anchored ephrin-A and transmembrane ephrin-B ligands including EFNA1 and EFNB3. Upon activation by ephrin ligands, modulates cell morphology and integrin-dependent cell adhesion through regulation of the Rac, Rap and Rho GTPases activity. Plays an important role in the development of the nervous system controlling different steps of axonal guidance including the establishment of the corticospinal projections. May also control the segregation of motor and sensory axons during neuromuscular circuit development. In addition to its role in axonal guidance plays a role in synaptic plasticity. Activated by EFNA1 phosphorylates CDK5 at 'Tyr-15' which in turn phosphorylates NGEF regulating RHOA and dendritic spine morphogenesis. In the nervous system, plays also a role in repair after injury preventing axonal regeneration and in angiogenesis playing a role in central nervous system vascular formation. Additionally, its promiscuity makes it available to participate in a variety of cell-cell signaling regulating for instance the development of the thymic epithelium.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1764R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1764R-CY7
Lokale Artikelnummer::
BOSSBS-1764R-CY7
Beschreibung:
Receptor tyrosine kinase which binds membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Highly promiscuous, it has the unique property among Eph receptors to bind and to be physiologically activated by both GPI-anchored ephrin-A and transmembrane ephrin-B ligands including EFNA1 and EFNB3. Upon activation by ephrin ligands, modulates cell morphology and integrin-dependent cell adhesion through regulation of the Rac, Rap and Rho GTPases activity. Plays an important role in the development of the nervous system controlling different steps of axonal guidance including the establishment of the corticospinal projections. May also control the segregation of motor and sensory axons during neuromuscular circuit development. In addition to its role in axonal guidance plays a role in synaptic plasticity. Activated by EFNA1 phosphorylates CDK5 at 'Tyr-15' which in turn phosphorylates NGEF regulating RHOA and dendritic spine morphogenesis. In the nervous system, plays also a role in repair after injury preventing axonal regeneration and in angiogenesis playing a role in central nervous system vascular formation. Additionally, its promiscuity makes it available to participate in a variety of cell-cell signaling regulating for instance the development of the thymic epithelium.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0693R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0693R-CY5
Lokale Artikelnummer::
BOSSBS-0693R-CY5
Beschreibung:
The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells. It may also induce apoptosis by sequestering VEGF-165. May bind as well various members of the semaphorin family. Its expression has an averse effect on blood vessel number and integrity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1315R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1315R-CY7
Lokale Artikelnummer::
BOSSBS-1315R-CY7
Beschreibung:
Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The reticulon protein is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, and as a facilitator of neurite branching. Reticulon 4 regulates neurite fasciculation, branching and extension in the developing nervous system. Involved in down-regulation of growth, stabilization of wiring and restriction of plasticity in the adult CNS. It regulates the radial migration of cortical neurons via an RTN4R-LINGO1 containing receptor complex. May inhibit BACE1 activity and amyloid precursor protein processing.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11190R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11190R-CY7
Lokale Artikelnummer::
BOSSBS-11190R-CY7
Beschreibung:
C9 is a plasma protein synthesized in the liver and monocytes consisting of a single polypeptide chain. C9 is a part of the membrane attack complex (MAC), an important component of the immune system. The MAC forms upon complement system activation by invading pathogenic bacteria and consists of the four major complement proteins: C5b, C6, C7 and C8. These complement proteins bind to the outer surface of the plasma membrane of the invading cell. C9 binds to the membrane associated C5b-8 protein, which leads to the circular polymerization of 12-18 C9 molecules. These polymerized C9 molecules form a ring structure in the membrane. Molecules can then diffuse freely through this transmembrane channel, causing cell lysis and destruction of the invading bacterial cell.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0156R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0156R-A750
Lokale Artikelnummer::
BOSSBS-0156R-A750
Beschreibung:
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1126R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1126R-A750
Lokale Artikelnummer::
BOSSBS-1126R-A750
Beschreibung:
Serotonin (pronounced) (5-hydroxytryptamine, or 5-HT) is a monoamine neurotransmitter synthesised in serotonergic neurons in the central nervous system (CNS) and enterochromaffin cells in the gastrointestinal tract of animals including humans. Serotonin is also found in many mushrooms and plants, including fruits and vegetables.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1126R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1126R-FITC
Lokale Artikelnummer::
BOSSBS-1126R-FITC
Beschreibung:
Serotonin (pronounced) (5-hydroxytryptamine, or 5-HT) is a monoamine neurotransmitter synthesized in serotonergic neurons in the central nervous system (CNS) and enterochromaffin cells in the gastrointestinal tract of animals including humans. Serotonin is also found in many mushrooms and plants, including fruits and vegetables.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0156R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0156R-A647
Lokale Artikelnummer::
BOSSBS-0156R-A647
Beschreibung:
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5873R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5873R-FITC
Lokale Artikelnummer::
BOSSBS-5873R-FITC
Beschreibung:
CNDP1 (Carnosine dipeptidase 1) belongs to the M20 metalloprotease family and is expressed in the adult nervous central system. It catalyzes preferential hydrolysis of the beta-Ala-|-His dipeptide (carnosine), and also anserine, Xaa-|-His dipeptides and other dipeptides including homocarnosine.
VE:
1 * 100 µl
Artikel-Nr:
(630-3433)
Lieferant:
LEICA MICROSYSTEMS
Hersteller-Artikelnummer::
13613750
Lokale Artikelnummer::
LEIM13613750
Beschreibung:
The AirTeach software bundle allows users to digitally share microscopy images from various microscope sources. Students are more engaged and inspired in an interactive learning environment that makes sharing and comparing of results fun for everyone.
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-3939R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3939R-A488
Lokale Artikelnummer::
BOSSBS-3939R-A488
Beschreibung:
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. Stimulates the Ras signaling pathway via RAPGEF2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11317R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11317R-A680
Lokale Artikelnummer::
BOSSBS-11317R-A680
Beschreibung:
Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3944R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3944R-CY5
Lokale Artikelnummer::
BOSSBS-3944R-CY5
Beschreibung:
GNG2 (Guanine nucleotide binding protein (G protein), gamma 2) is a member of the guanine nucleotide-binding proteins (G proteins) family. Heterotrimeric G proteins are involved as a modulator or transducer in various transmembrane signaling systems. The specificity of a G protein-receptor interaction is primarily mediated by the gamma subunit.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3944R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3944R-CY7
Lokale Artikelnummer::
BOSSBS-3944R-CY7
Beschreibung:
GNG2 (Guanine nucleotide binding protein (G protein), gamma 2) is a member of the guanine nucleotide-binding proteins (G proteins) family. Heterotrimeric G proteins are involved as a modulator or transducer in various transmembrane signaling systems. The specificity of a G protein-receptor interaction is primarily mediated by the gamma subunit.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3081R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3081R-CY7
Lokale Artikelnummer::
BOSSBS-3081R-CY7
Beschreibung:
CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity).
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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