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6-Bromo-3-chloro-2,4-difluoroaniline
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6-Bromo-3-chloro-2,4-difluoroaniline
Artikel-Nr:
(BOSSBS-0493R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0493R
Lokale Artikelnummer::
BOSSBS-0493R
Beschreibung:
TSARG1 is a 183 amino acid protein predominantly expressed in the testis. TSARG1 was initially discovered due to its possible role in spermatogenesis or spermatogenesis cell apoptosis and it may be linked to cell cycle control. Apoptosis during spermatogenesis is a natural occurrence and typically effects 75-80% of the germ cells. This high rate of apoptosis is required for normal mature speramatogenesis. It may be a consequence of mutated DNA but it is also believed to ensure a proper ratio between Sertoli cells and germ cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12462R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12462R-A647
Lokale Artikelnummer::
BOSSBS-12462R-A647
Beschreibung:
AGPS is a 658 amino acid enzyme that is required for glycerolipid metabolism and ether lipid biosynthesis. Localized to the inner aspect of the peroxisomal membrane, AGPS is likely part of a heterotrimeric complex that is also composed of GNPAT and a modified form of GNPAT. Containing one FAD-binding PCMH-type domain, AGPS utilizes FAD as a cofactor in the synthesis of alkyl-glycerone 3-phophate and a long-chain acid anion from 1-acteyl-glyerone 3-phosphate and a long-chain alcohol. Defects in the gene encoding AGPS results in rhizomelic chondrodysplasia punctata type 3, a disease characterized by vertebral disorders, severe mental retardation, cutaneous lesions, cataracts and rhizomelic shortening of the humerus and femur.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11051R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11051R-A488
Lokale Artikelnummer::
BOSSBS-11051R-A488
Beschreibung:
HAPLN2 is a 340 amino acid protein encoded by the human gene HAPLN2. HAPLN2 belongs to the HAPLN family and contains one immunoglobulin (Ig)-like, V-type domain and two link domains. HAPLN2 mediates a firm binding of versican V2 to hyaluronic acid. HAPLN2 is believed to play a pivotal role in the formation of the hyaluronan-associated matrix in the central nervous system (CNS), which facilitates neuronal conduction and general structural stabilization. HAPLN2 may also be involved in the formation of extracellular matrices, contributing to perineuronal nets and facilitating the understanding of a functional role of these extracellular matrices. HAPLN2 is found in several nuclei throughout the midbrain and hindbrain in a perineuronal net pattern.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11051R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11051R-A350
Lokale Artikelnummer::
BOSSBS-11051R-A350
Beschreibung:
HAPLN2 is a 340 amino acid protein encoded by the human gene HAPLN2. HAPLN2 belongs to the HAPLN family and contains one immunoglobulin (Ig)-like, V-type domain and two link domains. HAPLN2 mediates a firm binding of versican V2 to hyaluronic acid. HAPLN2 is believed to play a pivotal role in the formation of the hyaluronan-associated matrix in the central nervous system (CNS), which facilitates neuronal conduction and general structural stabilization. HAPLN2 may also be involved in the formation of extracellular matrices, contributing to perineuronal nets and facilitating the understanding of a functional role of these extracellular matrices. HAPLN2 is found in several nuclei throughout the midbrain and hindbrain in a perineuronal net pattern.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12462R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12462R-A488
Lokale Artikelnummer::
BOSSBS-12462R-A488
Beschreibung:
AGPS is a 658 amino acid enzyme that is required for glycerolipid metabolism and ether lipid biosynthesis. Localized to the inner aspect of the peroxisomal membrane, AGPS is likely part of a heterotrimeric complex that is also composed of GNPAT and a modified form of GNPAT. Containing one FAD-binding PCMH-type domain, AGPS utilizes FAD as a cofactor in the synthesis of alkyl-glycerone 3-phophate and a long-chain acid anion from 1-acteyl-glyerone 3-phosphate and a long-chain alcohol. Defects in the gene encoding AGPS results in rhizomelic chondrodysplasia punctata type 3, a disease characterized by vertebral disorders, severe mental retardation, cutaneous lesions, cataracts and rhizomelic shortening of the humerus and femur.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13076R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13076R-A350
Lokale Artikelnummer::
BOSSBS-13076R-A350
Beschreibung:
NPP6 is a 440 amino acid member of the nucleotide pyrophosphatase/phosphodiesterase family. NPP6 is a secreted and single-pass type I membrane protein. Predominantly expressed in brain and kidney, NPP6 is a choline-specific glycerophosphodiester phosphodiesterase. NPP6 can hydrolyze the classical substrate for phospholipase C, p-nitrophenyl phosphorylcholine, glycerophosphorylcholine, sphingosylphosphorylcholine and lysophosphatidylcholine (LPC). NPP6 has been found to have a preference for LPC with polyunsaturated or short fatty acids. The gene encoding NPP6 maps to human chromosome 4, which consists of approximately 6% of the human genome and nearly 900 genes. Chromosome 4 is associated with Huntington's disease, FGFR-3, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8874R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8874R-A680
Lokale Artikelnummer::
BOSSBS-8874R-A680
Beschreibung:
The G protein-coupled receptor TGR5 is a 330-amino acid protein that is almost universally expressed in human tissues including heart, skeletal muscle, spleen, kidney, liver, small intestine, placenta, and leukocytes, but not in brain, colon (without mucosa), thymus, or lung. TGR5 is sensitive to bile acids and responds through a significant mechanism that coordinates energy homeostasis. Bile acids activate mitogen-activated protein (MAP) kinase pathways, specifically induce TGR5 internalisation, promote an increase of guanosine 5'-O-3-thio-triphosphate binding in membrane fractions, and cause rapid intracellular cAMP production. Bile acids also provoke TGR5 to suppress macrophage functions. TGR5-controlled signaling pathways may be good candidates for drug targets to treat common metabolic diseases, such as obesity, type II diabetes, hyperlipidemia, and atherosclerosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12388R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12388R-A488
Lokale Artikelnummer::
BOSSBS-12388R-A488
Beschreibung:
KIF7 is a 1,343 amino acid protein expressed in embryonic stem cells, melanotic melanoma and Jurkat T-cells. KIF7 is a member of the KIF27 subfamily of the kinesin-like protein family and contains one kinesin-motor domain. It is suggested that KIF7 may participate in the Hedgehog (Hh) signaling pathway by regulating the proteolysis and stability of GLI transcription factors. Hedgehog (Hh) signaling plays a critical role in embryonic development.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12340R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12340R-A350
Lokale Artikelnummer::
BOSSBS-12340R-A350
Beschreibung:
Vanin-2 is a 520 amino acid GPI-anchor protein that belongs to the CN hydrolase family and BTD/VNN subfamily.Widely expressed with high expression in spleen and blood, vanin-2 is suggested to be involved in thymus homing of bone marrow cells, regulation of Integrin ∫2-mediated cell adhesion, and migration and motility of neutrophils. Vanin-2 exists as five alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 6q23.2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1163R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1163R-A750
Lokale Artikelnummer::
BOSSBS-1163R-A750
Beschreibung:
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. The mature form of Beta defensin 1 is 36 amino acids.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1163R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1163R-A680
Lokale Artikelnummer::
BOSSBS-1163R-A680
Beschreibung:
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. The mature form of Beta defensin 1 is 36 amino acids.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1163R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1163R-HRP
Lokale Artikelnummer::
BOSSBS-1163R-HRP
Beschreibung:
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. The mature form of Beta defensin 1 is 36 amino acids.
VE:
1 * 100 µl
Lieferant:
Honeywell Chemicals
Beschreibung:
Tetrachlorgold(III)säure Trihydrat ≥49,0% (Au-Basis) ACS, Fluka™
Artikel-Nr:
(BOSSBS-4604R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4604R-A488
Lokale Artikelnummer::
BOSSBS-4604R-A488
Beschreibung:
Leptin, the product of the ob (obese) gene, is a 16kD protein consisting of 146 amino acid residues. Leptin is produced in the adipose tissue, and is considered to play an important role in appetite control, fat metabolism and regulation of body weight. It targets the central nervous system, particularly hypothalamus, affecting food intake. Leptin levels are high in most obese individuals. Studies have shown that it may also influence reproductive function.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9355R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9355R-HRP
Lokale Artikelnummer::
BOSSBS-9355R-HRP
Beschreibung:
The gene encodes a 246-amino acid polypeptide containing an RNA binding motif, a putative nuclear localization signal, and phosphorylation sites. The alpha subunits comprises the outer rings of the proteasome. Some alpha subunits contain a functional nuclear localization signal; proteasomes are found in both the nuclear and cytoplasmic compartments of the cell. Alpha subunits may constitute a physical barrier that limits access of cytosolic proteins into the inner proteolytic chamber.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9355R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9355R-A647
Lokale Artikelnummer::
BOSSBS-9355R-A647
Beschreibung:
The gene encodes a 246-amino acid polypeptide containing an RNA binding motif, a putative nuclear localization signal, and phosphorylation sites. The alpha subunits comprises the outer rings of the proteasome. Some alpha subunits contain a functional nuclear localization signal; proteasomes are found in both the nuclear and cytoplasmic compartments of the cell. Alpha subunits may constitute a physical barrier that limits access of cytosolic proteins into the inner proteolytic chamber.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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