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IGEPAL\\\\\\\\u00AE+CA-630
Lieferant:
Alfa Aesar
Beschreibung:
Ammonium thiocyanate has many uses in manufacturing chemicals such as metal thiocyanates [CuSCN, Ca(SCN)2, NaSCN, KSCN], and in a number of pharmaceuticals. It is used in freezing solutions, pickling, printing, and corrosion inhibitor against acid gases. It is used in photography industry as a stabilizer or accelerator. Used in fertilizers, fabric dyeing, zinc coating, electroplating, and as a separator of Zr and Hf, also Au and Fe.
Artikel-Nr:
(BOSSBS-0231R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0231R-A750
Lokale Artikelnummer::
BOSSBS-0231R-A750
Beschreibung:
Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development and cephalic closure during embryonic development. Required for normal development of the mucosa lining the gastrointestinal tract, and for recruitment of mesenchymal cells and normal development of intestinal villi. Plays a role in cell migration and chemotaxis in wound healing. Plays a role in platelet activation, secretion of agonists from platelet granules, and in thrombin-induced platelet aggregation. Binding of its cognate ligands - homodimeric PDGFA, homodimeric PDGFB, heterodimers formed by PDGFA and PDGFB or homodimeric PDGFC -leads to the activation of several signaling cascades; the response depends on the nature of the bound ligand and is modulated by the formation of heterodimers between PDGFRA and PDGFRB. Phosphorylates PIK3R1, PLCG1, and PTPN11. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate, mobilisation of cytosolic Ca(2+) and the activation of protein kinase C. Phosphorylates PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and thereby mediates activation of the AKT1 signaling pathway. Mediates activation of HRAS and of the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. Promotes activation of STAT family members STAT1, STAT3 and STAT5A and/or STAT5B. Receptor signaling is down-regulated by protein phosphatases that dephosphorylate the receptor and its down-stream effectors, and by rapid internalisation of the activated receptor.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3160R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3160R-A750
Lokale Artikelnummer::
BOSSBS-3160R-A750
Beschreibung:
Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganisation of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis. Required for early embryonic development and placenta development. Required for embryonic angiogenesis, normal cardiomyocyte migration and proliferation, and normal heart development. Regulates axon growth and neuronal cell migration, axon branching and synapse formation; required for normal development of the nervous system. Plays a role in osteogenesis and differentiation of osteoblasts. Functions in integrin signal transduction, but also in signaling downstream of numerous growth factor receptors, G-protein coupled receptors (GPCR), EPHA2, netrin receptors and LDL receptors. Forms multisubunit signaling complexes with SRC and SRC family members upon activation; this leads to the phosphorylation of additional tyrosine residues, creating binding sites for scaffold proteins, effectors and substrates. Regulates numerous signaling pathways. Promotes activation of phosphatidylinositol 3-kinase and the AKT1 signaling cascade. Promotes activation of MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling cascade. Promotes localised and transient activation of guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs), and thereby modulates the activity of Rho family GTPases. Signaling via CAS family members mediates activation of RAC1. Recruits the ubiquitin ligase MDM2 to P53/TP53 in the nucleus, and thereby regulates P53/TP53 activity, P53/TP53 ubiquitination and proteasomal degradation. Phosphorylates SRC; this increases SRC kinase activity. Phosphorylates ACTN1, ARHGEF7, GRB7, RET and WASL.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3160R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3160R-FITC
Lokale Artikelnummer::
BOSSBS-3160R-FITC
Beschreibung:
Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis. Required for early embryonic development and placenta development. Required for embryonic angiogenesis, normal cardiomyocyte migration and proliferation, and normal heart development. Regulates axon growth and neuronal cell migration, axon branching and synapse formation; required for normal development of the nervous system. Plays a role in osteogenesis and differentiation of osteoblasts. Functions in integrin signal transduction, but also in signaling downstream of numerous growth factor receptors, G-protein coupled receptors (GPCR), EPHA2, netrin receptors and LDL receptors. Forms multisubunit signaling complexes with SRC and SRC family members upon activation; this leads to the phosphorylation of additional tyrosine residues, creating binding sites for scaffold proteins, effectors and substrates. Regulates numerous signaling pathways. Promotes activation of phosphatidylinositol 3-kinase and the AKT1 signaling cascade. Promotes activation of MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling cascade. Promotes localized and transient activation of guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs), and thereby modulates the activity of Rho family GTPases. Signaling via CAS family members mediates activation of RAC1. Recruits the ubiquitin ligase MDM2 to P53/TP53 in the nucleus, and thereby regulates P53/TP53 activity, P53/TP53 ubiquitination and proteasomal degradation. Phosphorylates SRC; this increases SRC kinase activity. Phosphorylates ACTN1, ARHGEF7, GRB7, RET and WASL.
VE:
1 * 100 µl
Artikel-Nr:
(KRAF20403.0000)
Lieferant:
Bernd Kraft
Hersteller-Artikelnummer::
20403.0000
Lokale Artikelnummer::
KRAF20403.0000
Beschreibung:
Calcium Standard, 10000 mg/L, Calcium, Matrix: 2 M HNO₃, Anwendung: AAS-Standards
VE:
1 * 100 mL
Artikel-Nr:
(BOSSBS-3400R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3400R-CY7
Lokale Artikelnummer::
BOSSBS-3400R-CY7
Beschreibung:
Non-receptor protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. Plays a role in the regulation of the humoral immune response, and is required for normal levels of marginal B-cells in the spleen and normal migration of splenic B-cells. Required for normal macrophage polarization and migration towards sites of inflammation. Regulates cytoskeleton rearrangement and cell spreading in T-cells, and contributes to the regulation of T-cell responses. Promotes osteoclastic bone resorption; this requires both PTK2B/PYK2 and SRC. May inhibit differentiation and activity of osteoprogenitor cells. Functions in signaling downstream of integrin and collagen receptors, immune receptors, G-protein coupled receptors (GPCR), cytokine, chemokine and growth factor receptors, and mediates responses to cellular stress. Forms multisubunit signaling complexes with SRC and SRC family members upon activation; this leads to the phosphorylation of additional tyrosine residues, creating binding sites for scaffold proteins, effectors and substrates. Regulates numerous signaling pathways. Promotes activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Regulates production of the cellular messenger cGMP. Promotes activation of the MAP kinase signaling cascade, including activation of MAPK1/ERK2, MAPK3/ERK1 and MAPK8/JNK1. Promotes activation of Rho family GTPases, such as RHOA and RAC1. Recruits the ubiquitin ligase MDM2 to P53/TP53 in the nucleus, and thereby regulates P53/TP53 activity, P53/TP53 ubiquitination and proteasomal degradation. Acts as a scaffold, binding to both PDPK1 and SRC, thereby allowing SRC to phosphorylate PDPK1 at 'Tyr-9, 'Tyr-373', and 'Tyr-376'. Promotes phosphorylation of NMDA receptors by SRC family members, and thereby contributes to the regulation of NMDA receptor ion channel activity and intracellular Ca(2+) levels.
VE:
1 * 100 µl
Artikel-Nr:
(PROOCON150-500-205)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CON150-500-205
Lokale Artikelnummer::
PROOCON150-500-205
Beschreibung:
Calcium Standard, 5000 µg/g, Calcium, Matrix: Base Oil 20, Anwendung: Ölbasierende Standards
VE:
1 * 50 g
Artikel-Nr:
(PROOCON150-100-205)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CON150-100-205
Lokale Artikelnummer::
PROOCON150-100-205
Beschreibung:
Calcium Standard, 1000 µg/g, Calcium, Matrix: Base Oil 20, Anwendung: Ölbasierende Standards
VE:
1 * 50 g
Artikel-Nr:
(PRSI91-409)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-409
Lokale Artikelnummer::
PRSI91-409
Beschreibung:
C-Type Lectin Domain Family 3 Member B (CLEC3B) is a serum and tissue protein and it contais a C-type lectin which binds to Ca++. CLEC3B is originally found in plasma, the concentrations approximately 10mg/l. It can bind to kringle 4 of plasminogen and enhance the activation of plaminogen to plasmin, catalyzed by tissue plasminogen activator in the presence of poly-D-lysine. In addition, CLEC3B may be involved in the packaging of molecules destined for exocytosis. Also, CLEC3B is best known as a prognostic marker in ovarian cancer.
VE:
1 * 50 µG
Lieferant:
Corning
Beschreibung:
PS-Flaschenaufsatz-Vakuumfilter mit nach Membrantyp farblich gekennzeichneten Adaptern: Polyethersulfon (PES) gelb; Celluloseacetat (CA) orange; Nylon (NY) rot.
Artikel-Nr:
(BOSSBS-3160R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3160R-CY3
Lokale Artikelnummer::
BOSSBS-3160R-CY3
Beschreibung:
Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis. Required for early embryonic development and placenta development. Required for embryonic angiogenesis, normal cardiomyocyte migration and proliferation, and normal heart development. Regulates axon growth and neuronal cell migration, axon branching and synapse formation; required for normal development of the nervous system. Plays a role in osteogenesis and differentiation of osteoblasts. Functions in integrin signal transduction, but also in signaling downstream of numerous growth factor receptors, G-protein coupled receptors (GPCR), EPHA2, netrin receptors and LDL receptors. Forms multisubunit signaling complexes with SRC and SRC family members upon activation; this leads to the phosphorylation of additional tyrosine residues, creating binding sites for scaffold proteins, effectors and substrates. Regulates numerous signaling pathways. Promotes activation of phosphatidylinositol 3-kinase and the AKT1 signaling cascade. Promotes activation of MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling cascade. Promotes localized and transient activation of guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs), and thereby modulates the activity of Rho family GTPases. Signaling via CAS family members mediates activation of RAC1. Recruits the ubiquitin ligase MDM2 to P53/TP53 in the nucleus, and thereby regulates P53/TP53 activity, P53/TP53 ubiquitination and proteasomal degradation. Phosphorylates SRC; this increases SRC kinase activity. Phosphorylates ACTN1, ARHGEF7, GRB7, RET and WASL.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI28-258)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-258
Lokale Artikelnummer::
PRSI28-258
Beschreibung:
TRPM5 is a voltage-modulated Ca (2+)-activated, monovalent cation channel (VCAM) that mediates a transient membrane depolarization and plays a central role in taste transduction. It is activated by arachidonic acid in vitro. It may be involved in perception of bitter, sweet and umami tastes. It may also be involved in sensing semiochemicals.
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-3400R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3400R-CY5
Lokale Artikelnummer::
BOSSBS-3400R-CY5
Beschreibung:
Non-receptor protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. Plays a role in the regulation of the humoral immune response, and is required for normal levels of marginal B-cells in the spleen and normal migration of splenic B-cells. Required for normal macrophage polarization and migration towards sites of inflammation. Regulates cytoskeleton rearrangement and cell spreading in T-cells, and contributes to the regulation of T-cell responses. Promotes osteoclastic bone resorption; this requires both PTK2B/PYK2 and SRC. May inhibit differentiation and activity of osteoprogenitor cells. Functions in signaling downstream of integrin and collagen receptors, immune receptors, G-protein coupled receptors (GPCR), cytokine, chemokine and growth factor receptors, and mediates responses to cellular stress. Forms multisubunit signaling complexes with SRC and SRC family members upon activation; this leads to the phosphorylation of additional tyrosine residues, creating binding sites for scaffold proteins, effectors and substrates. Regulates numerous signaling pathways. Promotes activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Regulates production of the cellular messenger cGMP. Promotes activation of the MAP kinase signaling cascade, including activation of MAPK1/ERK2, MAPK3/ERK1 and MAPK8/JNK1. Promotes activation of Rho family GTPases, such as RHOA and RAC1. Recruits the ubiquitin ligase MDM2 to P53/TP53 in the nucleus, and thereby regulates P53/TP53 activity, P53/TP53 ubiquitination and proteasomal degradation. Acts as a scaffold, binding to both PDPK1 and SRC, thereby allowing SRC to phosphorylate PDPK1 at 'Tyr-9, 'Tyr-373', and 'Tyr-376'. Promotes phosphorylation of NMDA receptors by SRC family members, and thereby contributes to the regulation of NMDA receptor ion channel activity and intracellular Ca(2+) levels.
VE:
1 * 100 µl
Artikel-Nr:
(MANA91324)
Lieferant:
MACHEREY-NAGEL
Hersteller-Artikelnummer::
91324
Lokale Artikelnummer::
MANA91324
Beschreibung:
QUANTOFIX® Teststäbchen erfüllen alle Anforderungen an einen modernen Schnelltest. Je nach Konzentration des Analyten in der Probe ändert sich die Farbe des Indikatorfeldes. Die Auswertung erfolgt meist visuell durch einen Vergleich der Reaktionsfarbe mit der mehrstufigen Farbskala. Die Teststäbchen sind für die einmalige Verwendung vorgesehen und müssen weder gewartet noch kalibriert werden.
VE:
1 * 100 Tests
Artikel-Nr:
(ABCAAB310883-100UL)
Lieferant:
Abcam
Beschreibung:
Anti-Calretinin Rabbit Monoclonal Antibody [clone: EP1798] (APC)
VE:
1 * 100 µl
Artikel-Nr:
(371706-10)
Lieferant:
Merck Millipore (Calbiochem)
Hersteller-Artikelnummer::
371706-10
Lokale Artikelnummer::
CALB371706-10
Beschreibung:
The GPR40 Agonist, also referenced under CAS 885101-89-3, controls the biological activity of GPR40. This small molecule/inhibitor is primarily used for Cell Signaling applications.
VE:
1 * 10 mg
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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