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INTEGRATED+DNA+TECHNOLOGIE
Artikel-Nr:
(BOSSBS-15497R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15497R-A680
Lokale Artikelnummer::
BOSSBS-15497R-A680
Beschreibung:
DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11226R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11226R-A750
Lokale Artikelnummer::
BOSSBS-11226R-A750
Beschreibung:
The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15497R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15497R-FITC
Lokale Artikelnummer::
BOSSBS-15497R-FITC
Beschreibung:
DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3293R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3293R-A750
Lokale Artikelnummer::
BOSSBS-3293R-A750
Beschreibung:
Mre11 is a component of the MRN complex, which plays a critical role in double-strand break repair (DSB), DNA recombination, maintenance of telomere integrity, and meiosis. Mre11 has both single-strand endonuclease and double strand-specific 3'-5' exonuclease activities. Rad50, another component of the MRN complex, is postulated to bind to DNA ends and hold them in close proximity, thus facilitating searches for regions of sequence homology, and also possibly stimulating the activity of DNA ligases and/or restricting Mre11 activity. Mutations in Mre11 may cause breast cancer.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3293R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3293R-CY3
Lokale Artikelnummer::
BOSSBS-3293R-CY3
Beschreibung:
Mre11 is a component of the MRN complex, which plays a critical role in double-strand break repair (DSB), DNA recombination, maintenance of telomere integrity, and meiosis. Mre11 has both single-strand endonuclease and double strand-specific 3'-5' exonuclease activities. Rad50, another component of the MRN complex, is postulated to bind to DNA ends and hold them in close proximity, thus facilitating searches for regions of sequence homology, and also possibly stimulating the activity of DNA ligases and/or restricting Mre11 activity. Mutations in Mre11 may cause breast cancer.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3293R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3293R-CY5
Lokale Artikelnummer::
BOSSBS-3293R-CY5
Beschreibung:
Mre11 is a component of the MRN complex, which plays a critical role in double-strand break repair (DSB), DNA recombination, maintenance of telomere integrity, and meiosis. Mre11 has both single-strand endonuclease and double strand-specific 3'-5' exonuclease activities. Rad50, another component of the MRN complex, is postulated to bind to DNA ends and hold them in close proximity, thus facilitating searches for regions of sequence homology, and also possibly stimulating the activity of DNA ligases and/or restricting Mre11 activity. Mutations in Mre11 may cause breast cancer.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3293R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3293R-A555
Lokale Artikelnummer::
BOSSBS-3293R-A555
Beschreibung:
Mre11 is a component of the MRN complex, which plays a critical role in double-strand break repair (DSB), DNA recombination, maintenance of telomere integrity, and meiosis. Mre11 has both single-strand endonuclease and double strand-specific 3'-5' exonuclease activities. Rad50, another component of the MRN complex, is postulated to bind to DNA ends and hold them in close proximity, thus facilitating searches for regions of sequence homology, and also possibly stimulating the activity of DNA ligases and/or restricting Mre11 activity. Mutations in Mre11 may cause breast cancer.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3293R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3293R-A647
Lokale Artikelnummer::
BOSSBS-3293R-A647
Beschreibung:
Mre11 is a component of the MRN complex, which plays a critical role in double-strand break repair (DSB), DNA recombination, maintenance of telomere integrity, and meiosis. Mre11 has both single-strand endonuclease and double strand-specific 3'-5' exonuclease activities. Rad50, another component of the MRN complex, is postulated to bind to DNA ends and hold them in close proximity, thus facilitating searches for regions of sequence homology, and also possibly stimulating the activity of DNA ligases and/or restricting Mre11 activity. Mutations in Mre11 may cause breast cancer.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11226R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11226R-HRP
Lokale Artikelnummer::
BOSSBS-11226R-HRP
Beschreibung:
The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11226R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11226R-CY7
Lokale Artikelnummer::
BOSSBS-11226R-CY7
Beschreibung:
The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11226R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11226R-A555
Lokale Artikelnummer::
BOSSBS-11226R-A555
Beschreibung:
The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11226R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11226R-A647
Lokale Artikelnummer::
BOSSBS-11226R-A647
Beschreibung:
The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11226R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11226R-CY3
Lokale Artikelnummer::
BOSSBS-11226R-CY3
Beschreibung:
The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5250R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5250R
Lokale Artikelnummer::
BOSSBS-5250R
Beschreibung:
The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3503R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3503R-A647
Lokale Artikelnummer::
BOSSBS-3503R-A647
Beschreibung:
Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. This could facilitate searches for short or long regions of sequence homology in the recombining DNA templates, and may also stimulate the activity of DNA ligases and/or restrict the nuclease activity of MRE11A to prevent nucleolytic degradation past a given point. The complex may also be required for DNA damage signaling via activation of the ATM kinase. In telomeres the MRN complex may modulate t-loop formation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12571R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12571R
Lokale Artikelnummer::
BOSSBS-12571R
Beschreibung:
Barrier-to-autointegration factor (BAF) binds non-specifically to double stranded DNA, possibly to play a role in tissue- or cell type-specific gene expression by interacting with different homeodomain transcription factors. BAF compresses chromatin structure and interacts with the LEM domain of nuclear proteins to play a crucial role in membrane recruitment and chromatin decondensation during nuclear assembly. Additionally, retroviruses like HIV-1 incorporate BAF from host cells into preintegration complexes (PICs) to prevent autointegration of retroviral DNA and thereby promote integration of retroviral DNA into the host chromosome.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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