INTEGRATED+DNA+TECHNOLOGIE
Artikel-Nr:
(BOSSBS-5623R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5623R-CY7
Lokale Artikelnummer::
BOSSBS-5623R-CY7
Beschreibung:
This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5623R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5623R-CY3
Lokale Artikelnummer::
BOSSBS-5623R-CY3
Beschreibung:
This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12329R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12329R-HRP
Lokale Artikelnummer::
BOSSBS-12329R-HRP
Beschreibung:
Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk (By similarity).
VE:
1 * 100 µl
Lieferant:
HICHROM GAS CHROMATOGRAPHY
Beschreibung:
Bietet eine Reihe von Selektivitäten mit unterschiedlichen Copolymerverhältnissen von PEG und Methylpolysiloxan. HI-PLUS, HI-PLUS 10, HI-PLUS 25, HI-PLUS 75, HI-PLUS 90.
Lieferant:
HICHROM GAS CHROMATOGRAPHY
Beschreibung:
Bietet eine Reihe von Selektivitäten mit unterschiedlichen Copolymerverhältnissen von PEG und Methylpolysiloxan. HI-PLUS, HI-PLUS 10, HI-PLUS 25, HI-PLUS 75, HI-PLUS 90.
Artikel-Nr:
(BOHLR1125-02)
Lieferant:
Bohlender
Hersteller-Artikelnummer::
R1125-02
Lokale Artikelnummer::
BOHLR1125-02
Beschreibung:
Sammelanschluss zum Sammeln von flüssigen Abfällen aus bis zu 2 HPLC-Anlagen. Kann direkt in Laborabzüge oder Arbeitstische integriert werden. b.safe Waste Pipes leiten flüssige Lösemittelabfälle direkt in angeschlossene Kanister weiter.
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-9067R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9067R-CY3
Lokale Artikelnummer::
BOSSBS-9067R-CY3
Beschreibung:
Huntington disease is associated with the expansion of a polyglutamine tract, greater than 35 repeats, in the HD gene product, huntingtin. HIP1, a membrane-associated protein, binds specifically to the N-terminus of human huntingtin. HIP1 is ubiquitously expressed in different brain regions at low levels and exhibits nearly identical subcellular fractionation as huntingtin. The HIP1 gene locates to the human chromosome 7q11.23. The huntingtin-HIP1 interaction is restricted to the brain and is inversely correlated to the polyglutamine length in the huntingtin, suggesting that loss of normal huntingtin-HIP1 interaction may compromise the membrane-cytoskeletal integrity in the brain. HIP1 contains an endocytic multidomain protein with a C-terminal Actin-binding domain, a central coiled-coil forming region and an N-terminal ENTH domain. HIP1 may be involved in vesicle trafficking; the structural integrity of HIP1 is crucial for maintenance of normal vesicle size in vivo. HIP12 is a non-proapoptotic member of the HIP gene family that is expressed in the brain and shares a similar subcellular distribution pattern with HIP1. However, HIP12 differs from HIP1 in its pattern of expression at both the mRNA and protein level. HIP12 does not directly interact with huntingtin but can interact with HIP1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9067R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9067R-A750
Lokale Artikelnummer::
BOSSBS-9067R-A750
Beschreibung:
Huntington disease is associated with the expansion of a polyglutamine tract, greater than 35 repeats, in the HD gene product, huntingtin. HIP1, a membrane-associated protein, binds specifically to the N-terminus of human huntingtin. HIP1 is ubiquitously expressed in different brain regions at low levels and exhibits nearly identical subcellular fractionation as huntingtin. The HIP1 gene locates to the human chromosome 7q11.23. The huntingtin-HIP1 interaction is restricted to the brain and is inversely correlated to the polyglutamine length in the huntingtin, suggesting that loss of normal huntingtin-HIP1 interaction may compromise the membrane-cytoskeletal integrity in the brain. HIP1 contains an endocytic multidomain protein with a C-terminal Actin-binding domain, a central coiled-coil forming region and an N-terminal ENTH domain. HIP1 may be involved in vesicle trafficking; the structural integrity of HIP1 is crucial for maintenance of normal vesicle sise <i>in vivo</i>. HIP12 is a non-proapoptotic member of the HIP gene family that is expressed in the brain and shares a similar subcellular distribution pattern with HIP1. However, HIP12 differs from HIP1 in its pattern of expression at both the mRNA and protein level. HIP12 does not directly interact with huntingtin but can interact with HIP1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9067R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9067R-A555
Lokale Artikelnummer::
BOSSBS-9067R-A555
Beschreibung:
Huntington disease is associated with the expansion of a polyglutamine tract, greater than 35 repeats, in the HD gene product, huntingtin. HIP1, a membrane-associated protein, binds specifically to the N-terminus of human huntingtin. HIP1 is ubiquitously expressed in different brain regions at low levels and exhibits nearly identical subcellular fractionation as huntingtin. The HIP1 gene locates to the human chromosome 7q11.23. The huntingtin-HIP1 interaction is restricted to the brain and is inversely correlated to the polyglutamine length in the huntingtin, suggesting that loss of normal huntingtin-HIP1 interaction may compromise the membrane-cytoskeletal integrity in the brain. HIP1 contains an endocytic multidomain protein with a C-terminal Actin-binding domain, a central coiled-coil forming region and an N-terminal ENTH domain. HIP1 may be involved in vesicle trafficking; the structural integrity of HIP1 is crucial for maintenance of normal vesicle size in vivo. HIP12 is a non-proapoptotic member of the HIP gene family that is expressed in the brain and shares a similar subcellular distribution pattern with HIP1. However, HIP12 differs from HIP1 in its pattern of expression at both the mRNA and protein level. HIP12 does not directly interact with huntingtin but can interact with HIP1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6691R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6691R-CY3
Lokale Artikelnummer::
BOSSBS-6691R-CY3
Beschreibung:
Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F1/TFDP1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of CDKN2A/p16INK4A.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9028R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9028R-CY3
Lokale Artikelnummer::
BOSSBS-9028R-CY3
Beschreibung:
Binds to regulatory subunit (RII) of protein kinase A. May be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream effectors to capture, amplify and focus diffuse, trans-cellular signals carried by cAMP (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5623R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5623R-A350
Lokale Artikelnummer::
BOSSBS-5623R-A350
Beschreibung:
This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6058R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6058R-CY5.5
Lokale Artikelnummer::
BOSSBS-6058R-CY5.5
Beschreibung:
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.
VE:
1 * 100 µl
Artikel-Nr:
(WLDM113714000-0080)
Lieferant:
WALDMANN
Hersteller-Artikelnummer::
113714000-0080
Lokale Artikelnummer::
WLDM113714000-0080
Beschreibung:
The TEVISIO magnifier luminaire delivers delight right across the range. Either in terms of fast and problem-free lens changes, the flexible lens ring with bayonet connection, or the perfectly conceived technical lighting concept or the visualiser function that suddenly also makes unseen errors visible.
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-12084R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12084R-HRP
Lokale Artikelnummer::
BOSSBS-12084R-HRP
Beschreibung:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7776R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7776R-CY5
Lokale Artikelnummer::
BOSSBS-7776R-CY5
Beschreibung:
Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.Tissue specificity:Detected in spleen, thymus, testis, ovary, small intestine and colon, with highest levels of expression in testis and ovary.
VE:
1 * 100 µl
Preis auf Anfrage
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