Imidazo[1,2-b]pyridazin
Artikel-Nr:
(BOSSBS-8204R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8204R-A647
Lokale Artikelnummer::
BOSSBS-8204R-A647
Beschreibung:
NEEP21, also known as Brain neuron cytoplasmic protein 1, NSG1 (neuron-specific proteins family member 1), P21 or D4S234E, is a single pass type II membrane protein belonging to the NSG family. It is highly expressed during neuronal maturation but its expression is downregulated in adult tissues. NEEP21 predominantly localizes to Rab 4-positive early endosomes in the somatodendritic neuronal compartment and is essential for proper receptor sorting and recycling in neurons. It associates with GRIP1 and GluR-2 and mediates the surface expression of GluR-2. When this interaction is interrupted, GluR-2 accumulates in early endosomes and leads to changes in evoked synaptic current properties. In addition, NEEP21 forms a complex with the SNARE protein, Syntaxin 13 (also known as Syntaxin 12), and participates in the recycling of transferrin receptors (TFRs) and NTR2 (neurotensin receptor 2).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3769R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3769R-CY5
Lokale Artikelnummer::
BOSSBS-3769R-CY5
Beschreibung:
Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.
VE:
1 * 100 µl
Artikel-Nr:
(BLEG573102)
Lieferant:
BIOLEGEND INC
Hersteller-Artikelnummer::
573102
Lokale Artikelnummer::
BLEG573102
Beschreibung:
Mouse recombinant IL-12 p40 homodimer insect cells
VE:
1 * 10 µG
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Lieferant:
SARSTEDT
Beschreibung:
Push cap, neutral, LDPE, Für Röhrchen: 75×12, 75×11,5, 55×12 mm, Für: Reagent and centrifuge tubes
Lieferant:
GRANT INSTRUMENTS
Beschreibung:
Replacement rotor R-05-02 for 12×0,5 ml and 12×0,2 ml microtubes, Für: Grant PCV-2400 / PCV-3000
Artikel-Nr:
(84864.600)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRC84864.600
Beschreibung:
Entspricht der Menge, die benötigt wird, um 1 l einer 0,1 M Lösung herzustellen.
VE:
1 * 170 mL
Lieferant:
ZEISS
Beschreibung:
Accessory for microscopes, Für: Microscope, LED spot 12 V/3×2 W
Artikel-Nr:
(521-2523)
Lieferant:
HERAEUS
Hersteller-Artikelnummer::
75003334
Lokale Artikelnummer::
HERA75003334
Beschreibung:
Festwinkelrotor, 6x94 ml, 16 260 g
VE:
1 * 1 ST
Artikel-Nr:
(84839.260)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRC84839.260
Beschreibung:
Chrom(III)chlorid Hexahydrat 98-101%, GPR RECTAPUR®
VE:
1 * 500 g
Lieferant:
Shenandoah Biotechnology
Beschreibung:
Interleukin 12 (IL-12) is an inducer of cell-mediated immunity and is produced by dendritic cells, macrophages, and B cells after antigen stimulation. IL-12 functions to promote naïve T cell differentiation into the type 1 T helper cell (Th1) lineage. IL-12 also stimulates the production of interferon gamma (IFN-γ) and tumor necrosis factor alpha (TNF-α) from T cells and natural killer cells. Mouse IL-12 is active on human and mouse cells.
Artikel-Nr:
(BOSSBS-3769R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3769R-HRP
Lokale Artikelnummer::
BOSSBS-3769R-HRP
Beschreibung:
Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11960R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11960R-HRP
Lokale Artikelnummer::
BOSSBS-11960R-HRP
Beschreibung:
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. SLITRK6 (SLIT and NTRK-like family, member 6) is an 841 amino acid single-pass type I membrane protein that contains 16 LRR repeats and belongs to the SLITRK family. Expressed at high levels in select brain tissue, as well as in both adult and fetal lung, SLITRK6 functions to suppress neurite outgrowth, playing a role in the regulation of neuronal function. Multiple isoforms of SLITRK6 exist due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3773R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3773R-A488
Lokale Artikelnummer::
BOSSBS-3773R-A488
Beschreibung:
Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3769R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3769R-A555
Lokale Artikelnummer::
BOSSBS-3769R-A555
Beschreibung:
Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11318R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11318R-A555
Lokale Artikelnummer::
BOSSBS-11318R-A555
Beschreibung:
The human ataxin-7 gene, also known as spinocerebellar ataxia 7 or SCA7, maps to chromosome 3p13-p12, has a 2,727-bp open reading frame, and encodes a 892 amino acid protein containing a nuclear localization signal and a polyglutamine tract (1,2). SCA7 is an autosomal dominant neurodegenerative disorder characterized by ataxia and selective neuronal cell loss caused by the expansion of a translated CAG repeat encoding a polyglutamine tract in ataxin-7, which is the SCA7 gene product (3,4). Ataxin-7 is expressed within neurons both affected and unaffected in SCA7 pathology with subcellular localization being variable depending upon the neuronal subtype (5). Polyglutamine expanded in ataxin-7 may carry out its pathogenic effects in the nucleus by altering the matrix-associated nuclear structure and/or by disrupting nucleolar function (6).
VE:
1 * 100 µl
Artikel-Nr:
(EHERC16405200)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C16405200
Lokale Artikelnummer::
EHERC16405200
Beschreibung:
Propylenglycol
VE:
1 * 1 mL
Preis auf Anfrage
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