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Imidazo[1,2-b]pyridazin
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Imidazo[1,2-b]pyridazin
Lieferant:
Alfa Aesar
Beschreibung:
tri-Natriumphosphat Dodecahydrat 98,0-102,0% ACS
Lieferant:
EPPENDORF
Beschreibung:
Adapter, für 17 Röhrchen 12×75 mm, für Rotor S-4×400, 2 Stück
Lieferant:
Thermo Scientific
Beschreibung:
N,N,N',N'-Tetramethylethylendiamin (TEMED) 99%, reinst
Artikel-Nr:
(730-1091)
Lieferant:
Simport Scientific
Hersteller-Artikelnummer::
T110-6
Lokale Artikelnummer::
SIMPT110-6
Beschreibung:
PS. The 1,2 ml capacity round bottom deep well plate (1 ml when capped) can withstand centrifugation up to 3000×g. It is not DMSO resistant.
VE:
1 * 24 ST
Artikel-Nr:
(BOSSBS-12312R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12312R-CY5
Lokale Artikelnummer::
BOSSBS-12312R-CY5
Beschreibung:
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The primary function of these motifs is to provide a versatile structural framework to mediate the formation of protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in genes encoding LRR-containing proteins. The leucine-rich repeat-containing protein 39 (LRRC39) is a 335 amino acid protein that contains nine LRR repeats and exists as two alternatively spliced isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13280R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13280R-CY7
Lokale Artikelnummer::
BOSSBS-13280R-CY7
Beschreibung:
The mammalian c-H-, c-K- and N-Ras proto-oncogenes encode ubiquitously expressed proteins (1,2). p21Ras can exist in either a physiologically quiescent GDP-binding state or a GTP-binding signal-emitting state (3). Oncogenic p21Ras proteins are trapped in the excited signal-emitting state because the mechanism normally employed to delimit their excitation period, hydrolysis of their bound GTP to GDP, is impaired as a result of specific mutations (3). Interaction of p21Ras with GTPase activating protein (GAP) can increase hydrolysis of p21Ras-bound GTP by as much as 1000-fold (4,5). The product of the neurofibromatosis type 1 gene (NF1) has also been shown to exhibit p21Ras GAP activity (6,7), and proteins that stimulate the GTPase activity of three other low molecular weight GTPases, including Rho, Rab 3A and Rap 1, have also been described (8,9).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11879R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11879R-CY7
Lokale Artikelnummer::
BOSSBS-11879R-CY7
Beschreibung:
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. Leucine-rich glioma-inactivated protein 3 (LGI3), also known as LGI1-like protein 4 (LGIL4) or leucine-rich repeat LGI family member 3, is a 548 amino acid secretory protein. LGI3 contains five LRR repeats and seven EAR repeats. Widely expressed, with highest levels in brain and lung, LGI3 has been shown to colocalize with endocytosis-associated proteins, lipid raft markers, and Syntaxin. The gene encoding LGI3 maps to chromosome 8p21.3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12312R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12312R-CY3
Lokale Artikelnummer::
BOSSBS-12312R-CY3
Beschreibung:
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The primary function of these motifs is to provide a versatile structural framework to mediate the formation of protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in genes encoding LRR-containing proteins. The leucine-rich repeat-containing protein 39 (LRRC39) is a 335 amino acid protein that contains nine LRR repeats and exists as two alternatively spliced isoforms.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
N,N,N',N'-Tetramethylethylendiamin (TEMED) für die Elektrophorese
Lieferant:
Alfa Aesar
Beschreibung:
Ammoniumeisen(III)sulfat Dodecahydrat 98,5-102,0% ACS
Artikel-Nr:
(MARI1800002)
Lieferant:
MARIENFELD
Hersteller-Artikelnummer::
1800002
Lokale Artikelnummer::
MARI1800002
Beschreibung:
Färbeplatte, Glas, B×T×H: 89×57×4,5 mm, Anzahl Wells: 12, Lochgröße: Ø×H: 15×1,5 mm
VE:
1 * 12 ST
Lieferant:
Lenz Laborglas GmbH & CO.KG
Beschreibung:
Sprayer head, 12 ml, NS 19/26
Artikel-Nr:
(BOSSBS-13522R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13522R-A488
Lokale Artikelnummer::
BOSSBS-13522R-A488
Beschreibung:
G protein-coupled receptors (GPRs or GPCRs), also known as seven transmembrane receptors, heptahelical receptors, or 7TM receptors, are members of the largest protein family and play a role in many different stimulus-response pathways. G-protein coupled receptors mediate extracellular signals into intracellular signals (G-protein activation). They respond to a great variety of signaling molecules, including hormones, neurotransmitters and other proteins and peptides. GPR proteins are integral seven-pass membrane proteins with some conserved amino acid regions. GPR19, an orphan receptor, shows elevated expression during embyronic development of the nervous sytem as well as in specific regions of adult mouse brain, including the olfactory bulb, the hippocampus, hypothalamic nuclei and the cerebellum. The GPR19 gene maps to a location on chromosome 12, which is a frequent target for rearrangement in cancer cells and involved in childhood acute lymphoblastic leukemia (ALL).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9025R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9025R-FITC
Lokale Artikelnummer::
BOSSBS-9025R-FITC
Beschreibung:
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. ISLR2 (immunoglobulin superfamily containing leucine-rich repeat 2), also known as LINX (leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein), is a 745 amino acid single-pass membrane protein that contains five LRR repeats, one Ig-like (immunoglobulin-like) domain, a LRRCT domain and one LRRNT domain. ISLR2 exists as a homomultimer and is essential for axon extension during neural development. The gene encoding ISLR2 maps to human chromosome 15q24.1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12475R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12475R-HRP
Lokale Artikelnummer::
BOSSBS-12475R-HRP
Beschreibung:
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. ANKK1 (ankyrin repeat and kinase domain containing 1), also known as PKK2 or SGK288, is a 765 amino acid protein that belongs to the Ser/Thr protein kinase family and contains 12 ANK repeats and one protein kinase domain. Highly expressed in brain tissue and present in lower amounts in placenta and spinal cord, ANKK1 functions to catalyze the ATP-dependent phosphorylation of target proteins and is thought to play a role in alcohol and nicotine dependence. The gene encoding ANKK1 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8042R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8042R-FITC
Lokale Artikelnummer::
BOSSBS-8042R-FITC
Beschreibung:
The Major facilitator superfamily consists of presumed carbohydrate transporters with 10-12 membrane-spanning domains. Belonging to the facilitator superfamily, HIAT1 is a 490 amino acid multi-pass membrane protein that may function as a sugar transporter and is expressed in adult and embryonic brain. The HIAT1 gene was first observed while analyzing for active genes in neonatal mouse hippocampus. The gene encoding HIAT1 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. Stickler syndrome, Parkinsons, schizophrenia, familial adenomatous polyposis, Gaucher disease and Usher syndrome are also associated with chromosome 1.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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