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3-Bromo-4-chloro-5-(trifluoromethyl)phenylacetic+acid
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3-Bromo-4-chloro-5-(trifluoromethyl)phenylacetic+acid
Artikel-Nr:
(BOSSBS-4775R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4775R-CY5
Lokale Artikelnummer::
BOSSBS-4775R-CY5
Beschreibung:
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2594R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2594R-HRP
Lokale Artikelnummer::
BOSSBS-2594R-HRP
Beschreibung:
Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex.
VE:
1 * 100 µl
Artikel-Nr:
(ROCK600-401-398)
Lieferant:
Rockland Immunochemicals
Hersteller-Artikelnummer::
600-401-398
Lokale Artikelnummer::
ROCK600-401-398
Beschreibung:
Affinity purified rabbit anti-ATM has been tested by ELISA, immunofluorescence microscopy, western blotting and biological assays against both the native and recombinant forms of the Protein.
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-5340R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5340R-CY3
Lokale Artikelnummer::
BOSSBS-5340R-CY3
Beschreibung:
ErbB3 is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ErbB3 is a membrane-bound protein which has a neuregulin binding domain but not an active kinase domain. It can therefore bind this ligand but cannot convey a signal into the cell via protein phosphorylation. However it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers including prostate, bladder and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. Isoform 2 lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported but they have not been thoroughly characterized. Defects in ERBB3 are the cause of lethal congenital contracture syndrome type 2 (LCCS2); also called Israeli Bedouin multiple contracture syndrome type A. LCCS2 is an autosomal recessive neurogenic form of a neonatally lethal arthrogryposis that is associated with atrophy of the anterior horn of the spinal cord.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2897R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2897R-A488
Lokale Artikelnummer::
BOSSBS-2897R-A488
Beschreibung:
ErbB3 is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ErbB3 is a membrane-bound protein which has a neuregulin binding domain but not an active kinase domain. It can therefore bind this ligand but cannot convey a signal into the cell via protein phosphorylation. However it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers including prostate, bladder and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. Isoform 2 lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported but they have not been thoroughly characterized. Defects in ERBB3 are the cause of lethal congenital contracture syndrome type 2 (LCCS2); also called Israeli Bedouin multiple contracture syndrome type A. LCCS2 is an autosomal recessive neurogenic form of a neonatally lethal arthrogryposis that is associated with atrophy of the anterior horn of the spinal cord.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2897R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2897R-A350
Lokale Artikelnummer::
BOSSBS-2897R-A350
Beschreibung:
ErbB3 is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ErbB3 is a membrane-bound protein which has a neuregulin binding domain but not an active kinase domain. It can therefore bind this ligand but cannot convey a signal into the cell via protein phosphorylation. However it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers including prostate, bladder and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. Isoform 2 lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported but they have not been thoroughly characterized. Defects in ERBB3 are the cause of lethal congenital contracture syndrome type 2 (LCCS2); also called Israeli Bedouin multiple contracture syndrome type A. LCCS2 is an autosomal recessive neurogenic form of a neonatally lethal arthrogryposis that is associated with atrophy of the anterior horn of the spinal cord.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5340R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5340R-A555
Lokale Artikelnummer::
BOSSBS-5340R-A555
Beschreibung:
ErbB3 is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ErbB3 is a membrane-bound protein which has a neuregulin binding domain but not an active kinase domain. It can therefore bind this ligand but cannot convey a signal into the cell via protein phosphorylation. However it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers including prostate, bladder and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. Isoform 2 lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported but they have not been thoroughly characterized. Defects in ERBB3 are the cause of lethal congenital contracture syndrome type 2 (LCCS2); also called Israeli Bedouin multiple contracture syndrome type A. LCCS2 is an autosomal recessive neurogenic form of a neonatally lethal arthrogryposis that is associated with atrophy of the anterior horn of the spinal cord.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11561R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11561R-HRP
Lokale Artikelnummer::
BOSSBS-11561R-HRP
Beschreibung:
Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterized by loss of motor neurons in the spinal cord. SMA is caused by deletion or loss-of-function mutations of SMN (survival of motor neuron) gene. SMN, also known as Gemin1, SMN1, SMNT and BCD541, exists as four isoforms produced by alternative splicing. SMN is oligomeric and forms a complex with Gemin2 (formerly SIP1), Gemin3 (a DEAD box RNA helicase), Gemin4, Gemin5 and Gemin6, as well as several spliceosomal snRNP proteins. The SMN complex plays an essential role in splicesomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus. The SMN complex is found in both the cytoplasm and the nucleus. The nuclear form is concentrated in subnuclear bodies called gems (gemini of the coiled bodies). Cytoplasmic SMN interacts with spliceosomal Sm proteins and facilitates their assembly onto U snRNAs, and nuclear SMN mediates recycling of pre-mRNA splicing factors. Nearly identical telomeric and centromeric forms of SMN encode the same protein; however, only mutations in the telomeric form are associated with the disease-state SMA. SMN is expresed in a wide variety of tissues including brain, kidney, liver, spinal cord and moderately in skeletal and cardiac muscle.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5141R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5141R-CY3
Lokale Artikelnummer::
BOSSBS-5141R-CY3
Beschreibung:
Matrin 3 (MATR 3) is an internal nuclear matrix protein that may play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer MATR 3 may play a role in nuclear retention of defective RNAs. MATR3 forms part of complex consisting of SFPQ, NONO and MATR3.The protein contains 1 matrin type zinc finger and 2 RRM (RNA recognition motif) domains. Two transcript variants encoding the same protein have been identified for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1554R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1554R-A680
Lokale Artikelnummer::
BOSSBS-1554R-A680
Beschreibung:
Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6716R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6716R-A680
Lokale Artikelnummer::
BOSSBS-6716R-A680
Beschreibung:
Uricase catalyzes the oxidation of uric acid to 5 hydroxyisourate which spontaneously decomposes to form allantoin.
VE:
1 * 100 µl
Artikel-Nr:
(BSENM-1249-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
M-1249-100
Lokale Artikelnummer::
BSENM-1249-100
Beschreibung:
X63 is a control mouse IgG antibody with no known reactivity. The antibody has been used successfully a negative control in westerns, all forms of IHC, IP and FACS
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-1554R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1554R-A647
Lokale Artikelnummer::
BOSSBS-1554R-A647
Beschreibung:
Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8372R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8372R-A555
Lokale Artikelnummer::
BOSSBS-8372R-A555
Beschreibung:
E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13092R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13092R-HRP
Lokale Artikelnummer::
BOSSBS-13092R-HRP
Beschreibung:
ErbB3 is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ErbB3 is a membrane-bound protein which has a neuregulin binding domain but not an active kinase domain. It can therefore bind this ligand but cannot convey a signal into the cell via protein phosphorylation. However it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers including prostate, bladder and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. Isoform 2 lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported but they have not been thoroughly characterized. Defects in ERBB3 are the cause of lethal congenital contracture syndrome type 2 (LCCS2); also called Israeli Bedouin multiple contracture syndrome type A. LCCS2 is an autosomal recessive neurogenic form of a neonatally lethal arthrogryposis that is associated with atrophy of the anterior horn of the spinal cord.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5340R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5340R-CY5.5
Lokale Artikelnummer::
BOSSBS-5340R-CY5.5
Beschreibung:
ErbB3 is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ErbB3 is a membrane-bound protein which has a neuregulin binding domain but not an active kinase domain. It can therefore bind this ligand but cannot convey a signal into the cell via protein phosphorylation. However it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers including prostate, bladder and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. Isoform 2 lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported but they have not been thoroughly characterized. Defects in ERBB3 are the cause of lethal congenital contracture syndrome type 2 (LCCS2); also called Israeli Bedouin multiple contracture syndrome type A. LCCS2 is an autosomal recessive neurogenic form of a neonatally lethal arthrogryposis that is associated with atrophy of the anterior horn of the spinal cord.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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