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L(-)-Glutathion+(oxidierte+Form)
Artikel-Nr:
(BOSSBS-5004R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5004R-A680
Lokale Artikelnummer::
BOSSBS-5004R-A680
Beschreibung:
PFKFB1 belongs to the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. It forms a homodimer that is involved in both the synthesis and degradation of fructose 2,6-bisphosphate. The activity of this enzyme is thought to regulate glucose homeostasis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1558R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1558R-A555
Lokale Artikelnummer::
BOSSBS-1558R-A555
Beschreibung:
Stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2723R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2723R-CY3
Lokale Artikelnummer::
BOSSBS-2723R-CY3
Beschreibung:
May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9452R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9452R-CY3
Lokale Artikelnummer::
BOSSBS-9452R-CY3
Beschreibung:
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7741R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7741R-CY5
Lokale Artikelnummer::
BOSSBS-7741R-CY5
Beschreibung:
Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3862R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3862R-CY7
Lokale Artikelnummer::
BOSSBS-3862R-CY7
Beschreibung:
SCAP is an escort protein required for cholestrol and lipid homeostasis. Cholesterol homeostasis in animal cells is achieved by regulated cleavage of SREBPs, membrane-bound transcription factors. SCAP forms a complex with SREBPs in order to release the active domains of SREBPs.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3862R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3862R-CY3
Lokale Artikelnummer::
BOSSBS-3862R-CY3
Beschreibung:
SCAP is an escort protein required for cholestrol and lipid homeostasis. Cholesterol homeostasis in animal cells is achieved by regulated cleavage of SREBPs, membrane-bound transcription factors. SCAP forms a complex with SREBPs in order to release the active domains of SREBPs.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1295R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1295R-CY5.5
Lokale Artikelnummer::
BOSSBS-1295R-CY5.5
Beschreibung:
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation. [provided by RefSeq, Jul 2008]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8071R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8071R-A750
Lokale Artikelnummer::
BOSSBS-8071R-A750
Beschreibung:
May be a chaperone-like protein essential for the proper conformation and functioning of protein complexes in the respiratory chain.Tissue specificity:Ubiquitously expressed with a relatively greater abundance in heart and skeletal muscle.Involvement in disease:Defects in ADCK3 are a cause of coenzyme Q10 deficiency (CoQ10 deficiency). CoQ10 deficiency is an autosomal recessive disorder with variable manifestations. It can be associated with three main clinical phenotypes: a predominantly myopathic form with central nervous system involvement, an infantile encephalomyopathy with renal dysfunction and an ataxic form with cerebellar atrophy.Defects in ADCK3 are the cause of spinocerebellar ataxia autosomal recessive type 9 (SCAR9) [MIM:612016]; also known as autosomal recessive cerebellar ataxia type 2 (ARCA2). Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCAR9 is an autosomal recessive form characterised by gait ataxia and cerebellar atrophy with slow progression and few associated features. Patients can manifest brisk tendon reflexes and Hoffmann sign, mild psychomotor retardation, mild axonal degeneration of the sural nerve, exercise intolerance and elevated serum lactate.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12141R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12141R-HRP
Lokale Artikelnummer::
BOSSBS-12141R-HRP
Beschreibung:
LRFN1 is a 771 amino acid single-pass type I membrane protein that belongs to the LRFN family. Containing a fibronectin type-III domain, an Ig-like (immunoglobulin-like) domain, a LRRCT domain, a LRRNT domain and seven LRR (leucine-rich) repeats, LRFN1 is thought to promote neurite outgrowth in hippocampal neurons and is involved in the regulation and maintenance of excitatory synapses. LRFN1 forms heteromeric complexes with LRFN2, LRFN3, LFRN4 and LFRN5, but does not have the ability to form homomeric complexes across cell junctions of adjacent cells like other LRFN family members. The PDZ-binding motif of LRFN1 is required for neurite outgrowth promotion and for SAP 97-, NE-dlg- and PSD-95-binding. LRFN1 is encoded by a gene located on human chromosome 19q13.2 and mouse chromosome 7 A3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2158R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2158R-A555
Lokale Artikelnummer::
BOSSBS-2158R-A555
Beschreibung:
Functions as a calcium permeable cation channel involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. Together with TRPV4, forms mechano- and thermosensitive channels in cilium (PubMed:18695040). PKD1 and PKD2 may function through a common signaling pathway that is necessary for normal tubulogenesis. Acts as a regulator of cilium length, together with PKD1. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling. Also involved in left/right axis specification downstream of nodal flow: forms a complex with PKD1L1 in cilia to facilitate flow detection in left/right patterning (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13198R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13198R-A488
Lokale Artikelnummer::
BOSSBS-13198R-A488
Beschreibung:
The v-Fos oncogene was initially identified as the transforming gene of two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. The cellular homolog, c-Fos, encodes a nuclear phosphoprotein that is rapidly and transiently induced by a variety of agents and functions as a transcriptional regulator for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers which bind to specific DNA TPA response elements (TREs), c-Fos proteins are only active as heterodimers with members of the Jun gene family. Murine Fos B encodes a nuclear protein of 338 amino acids which has 70% homology with c-Fos, exhibits similar kinetics of expression as c-Fos and forms heterodimers with both c-Jun and Jun B which bind to TRE DNA response elements. Functional homologs of c-Fos and Fos B include Fra-1 and Fra-2 genes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12414R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12414R-CY5
Lokale Artikelnummer::
BOSSBS-12414R-CY5
Beschreibung:
MISR II is a 573 amino acid protein encoded by the human gene AMHR2. MISR II belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily and contains one protein kinase domain. Upon ligand binding, MISR II forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. These type II receptors rylate and activate type I receptors which autophosphorylate, then bind and activate Smad transcriptional regulators. MISR II also acts as a receptor for anti-Muellerian hormone. Defects in AMHR2 are the cause of persistent Muellerian duct syndrome type 2 (PMDS-2). PMDS-2 is a form of male pseudo-hermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12414R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12414R-A488
Lokale Artikelnummer::
BOSSBS-12414R-A488
Beschreibung:
MISR II is a 573 amino acid protein encoded by the human gene AMHR2. MISR II belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily and contains one protein kinase domain. Upon ligand binding, MISR II forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. These type II receptors rylate and activate type I receptors which autophosphorylate, then bind and activate Smad transcriptional regulators. MISR II also acts as a receptor for anti-Muellerian hormone. Defects in AMHR2 are the cause of persistent Muellerian duct syndrome type 2 (PMDS-2). PMDS-2 is a form of male pseudo-hermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2158R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2158R-A680
Lokale Artikelnummer::
BOSSBS-2158R-A680
Beschreibung:
Functions as a calcium permeable cation channel involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. Together with TRPV4, forms mechano- and thermosensitive channels in cilium (PubMed:18695040). PKD1 and PKD2 may function through a common signaling pathway that is necessary for normal tubulogenesis. Acts as a regulator of cilium length, together with PKD1. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling. Also involved in left/right axis specification downstream of nodal flow: forms a complex with PKD1L1 in cilia to facilitate flow detection in left/right patterning (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13198R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13198R-A555
Lokale Artikelnummer::
BOSSBS-13198R-A555
Beschreibung:
The v-Fos oncogene was initially identified as the transforming gene of two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. The cellular homolog, c-Fos, encodes a nuclear phosphoprotein that is rapidly and transiently induced by a variety of agents and functions as a transcriptional regulator for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers which bind to specific DNA TPA response elements (TREs), c-Fos proteins are only active as heterodimers with members of the Jun gene family. Murine Fos B encodes a nuclear protein of 338 amino acids which has 70% homology with c-Fos, exhibits similar kinetics of expression as c-Fos and forms heterodimers with both c-Jun and Jun B which bind to TRE DNA response elements. Functional homologs of c-Fos and Fos B include Fra-1 and Fra-2 genes.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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