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L(-)-Glutathion+(oxidierte+Form)
Artikel-Nr:
(BOSSBS-9668R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9668R-CY5.5
Lokale Artikelnummer::
BOSSBS-9668R-CY5.5
Beschreibung:
Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4039R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4039R-A488
Lokale Artikelnummer::
BOSSBS-4039R-A488
Beschreibung:
SLC37A4 transports glucose-6-phosphate from the cytoplasm to the lumen of the endoplasmic reticulum. It forms a complex with glucose-6-phosphatase which is responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it plays a central role in homeostatic regulation of blood glucose levels.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11364R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11364R-HRP
Lokale Artikelnummer::
BOSSBS-11364R-HRP
Beschreibung:
The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex. Biochemical studies have identified additional binding partners. As part of the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1 complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules. Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10454R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10454R-A750
Lokale Artikelnummer::
BOSSBS-10454R-A750
Beschreibung:
Non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. C4A isotype is responsible for effective binding to form amide bonds with immune aggregates or protein antigens, while C4B isotype catalyses the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens. Derived from proteolytic degradation of complement C4, C4a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5198R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5198R-A555
Lokale Artikelnummer::
BOSSBS-5198R-A555
Beschreibung:
Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5198R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5198R-A488
Lokale Artikelnummer::
BOSSBS-5198R-A488
Beschreibung:
Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5198R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5198R-A647
Lokale Artikelnummer::
BOSSBS-5198R-A647
Beschreibung:
Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5004R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5004R-CY7
Lokale Artikelnummer::
BOSSBS-5004R-CY7
Beschreibung:
PFKFB1 belongs to the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. It forms a homodimer that is involved in both the synthesis and degradation of fructose 2,6-bisphosphate. The activity of this enzyme is thought to regulate glucose homeostasis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5004R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5004R-CY5.5
Lokale Artikelnummer::
BOSSBS-5004R-CY5.5
Beschreibung:
PFKFB1 belongs to the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. It forms a homodimer that is involved in both the synthesis and degradation of fructose 2,6-bisphosphate. The activity of this enzyme is thought to regulate glucose homeostasis.
VE:
1 * 100 µl
Artikel-Nr:
(ROCK100-401-266)
Lieferant:
Rockland Immunochemicals
Hersteller-Artikelnummer::
100-401-266
Lokale Artikelnummer::
ROCK100-401-266
Beschreibung:
Anti-phospho NFkB antibody reacts human pS529 p65 and shows minimal reactivity by western blot with non-phosphorylated p65 and minimal reactivity by ELISA against the non-phosphorylated form of the immunizing peptide.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13545R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13545R-A350
Lokale Artikelnummer::
BOSSBS-13545R-A350
Beschreibung:
Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble form, known as GCS or sGC, act as receptors for nitric oxide (NO). The membrane-bound receptor form, known as GC, are peptide hormone receptors. GCS is a cGMP-synthesizing enzyme, which is the major receptor for the neurotransmitter nitric oxide. It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme-containing heterodimer, consisting of one alpha subunit and one beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide (CO), which weakly stimulates the enzyme. Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, YC-1. YC-1 can also stimulate GCS in a NO-independent manner. Both alpha and beta subunits are required for cGMP generation, and at least two isoforms exist for each subunit. Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, and both display similar enzymatic activity. The distribution of the beta-2 subunit seems to be much more restricted than the beta-1 subunit, with predominant expression in kidney and liver.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13545R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13545R-HRP
Lokale Artikelnummer::
BOSSBS-13545R-HRP
Beschreibung:
Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble form, known as GCS or sGC, act as receptors for nitric oxide (NO). The membrane-bound receptor form, known as GC, are peptide hormone receptors. GCS is a cGMP-synthesizing enzyme, which is the major receptor for the neurotransmitter nitric oxide. It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme-containing heterodimer, consisting of one alpha subunit and one beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide (CO), which weakly stimulates the enzyme. Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, YC-1. YC-1 can also stimulate GCS in a NO-independent manner. Both alpha and beta subunits are required for cGMP generation, and at least two isoforms exist for each subunit. Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, and both display similar enzymatic activity. The distribution of the beta-2 subunit seems to be much more restricted than the beta-1 subunit, with predominant expression in kidney and liver.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13545R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13545R-A680
Lokale Artikelnummer::
BOSSBS-13545R-A680
Beschreibung:
Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble form, known as GCS or sGC, act as receptors for nitric oxide (NO). The membrane-bound receptor form, known as GC, are peptide hormone receptors. GCS is a cGMP-synthesizing enzyme, which is the major receptor for the neurotransmitter nitric oxide. It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme-containing heterodimer, consisting of one alpha subunit and one beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide (CO), which weakly stimulates the enzyme. Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, YC-1. YC-1 can also stimulate GCS in a NO-independent manner. Both alpha and beta subunits are required for cGMP generation, and at least two isoforms exist for each subunit. Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, and both display similar enzymatic activity. The distribution of the beta-2 subunit seems to be much more restricted than the beta-1 subunit, with predominant expression in kidney and liver.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13545R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13545R-A488
Lokale Artikelnummer::
BOSSBS-13545R-A488
Beschreibung:
Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble form, known as GCS or sGC, act as receptors for nitric oxide (NO). The membrane-bound receptor form, known as GC, are peptide hormone receptors. GCS is a cGMP-synthesizing enzyme, which is the major receptor for the neurotransmitter nitric oxide. It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme-containing heterodimer, consisting of one alpha subunit and one beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide (CO), which weakly stimulates the enzyme. Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, YC-1. YC-1 can also stimulate GCS in a NO-independent manner. Both alpha and beta subunits are required for cGMP generation, and at least two isoforms exist for each subunit. Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, and both display similar enzymatic activity. The distribution of the beta-2 subunit seems to be much more restricted than the beta-1 subunit, with predominant expression in kidney and liver.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1295R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1295R-CY7
Lokale Artikelnummer::
BOSSBS-1295R-CY7
Beschreibung:
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation. [provided by RefSeq, Jul 2008]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2305R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2305R-HRP
Lokale Artikelnummer::
BOSSBS-2305R-HRP
Beschreibung:
E2 EPF is a member of the ubiquitin conjugating enzyme family. It is able to form a thiol ester linkage with ubiquitin in a ubiquitin activating enzyme dependent manner, a characteristic property of ubiquitin carrier proteins.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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