L(-)-Glutathion+(oxidierte+Form)
Artikel-Nr:
(BOSSBS-1295R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1295R-A647
Lokale Artikelnummer::
BOSSBS-1295R-A647
Beschreibung:
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation. [provided by RefSeq, Jul 2008]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4039R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4039R-A680
Lokale Artikelnummer::
BOSSBS-4039R-A680
Beschreibung:
SLC37A4 transports glucose-6-phosphate from the cytoplasm to the lumen of the endoplasmic reticulum. It forms a complex with glucose-6-phosphatase which is responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it plays a central role in homeostatic regulation of blood glucose levels.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4039R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4039R-A555
Lokale Artikelnummer::
BOSSBS-4039R-A555
Beschreibung:
SLC37A4 transports glucose-6-phosphate from the cytoplasm to the lumen of the endoplasmic reticulum. It forms a complex with glucose-6-phosphatase which is responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it plays a central role in homeostatic regulation of blood glucose levels.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1111R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1111R-FITC
Lokale Artikelnummer::
BOSSBS-1111R-FITC
Beschreibung:
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3862R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3862R-HRP
Lokale Artikelnummer::
BOSSBS-3862R-HRP
Beschreibung:
SCAP is an escort protein required for cholestrol and lipid homeostasis. Cholesterol homeostasis in animal cells is achieved by regulated cleavage of SREBPs, membrane-bound transcription factors. SCAP forms a complex with SREBPs in order to release the active domains of SREBPs.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5334R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5334R-CY7
Lokale Artikelnummer::
BOSSBS-5334R-CY7
Beschreibung:
Regulates eIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7057R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7057R-CY3
Lokale Artikelnummer::
BOSSBS-7057R-CY3
Beschreibung:
Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7728R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7728R
Lokale Artikelnummer::
BOSSBS-7728R
Beschreibung:
SMC4 is a central component of the condensin complex, which is required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5198R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5198R-A750
Lokale Artikelnummer::
BOSSBS-5198R-A750
Beschreibung:
Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5198R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5198R-A680
Lokale Artikelnummer::
BOSSBS-5198R-A680
Beschreibung:
Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4039R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4039R-A488
Lokale Artikelnummer::
BOSSBS-4039R-A488
Beschreibung:
SLC37A4 transports glucose-6-phosphate from the cytoplasm to the lumen of the endoplasmic reticulum. It forms a complex with glucose-6-phosphatase which is responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it plays a central role in homeostatic regulation of blood glucose levels.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13198R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13198R-A350
Lokale Artikelnummer::
BOSSBS-13198R-A350
Beschreibung:
The v-Fos oncogene was initially identified as the transforming gene of two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. The cellular homolog, c-Fos, encodes a nuclear phosphoprotein that is rapidly and transiently induced by a variety of agents and functions as a transcriptional regulator for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers which bind to specific DNA TPA response elements (TREs), c-Fos proteins are only active as heterodimers with members of the Jun gene family. Murine Fos B encodes a nuclear protein of 338 amino acids which has 70% homology with c-Fos, exhibits similar kinetics of expression as c-Fos and forms heterodimers with both c-Jun and Jun B which bind to TRE DNA response elements. Functional homologs of c-Fos and Fos B include Fra-1 and Fra-2 genes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2158R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2158R-HRP
Lokale Artikelnummer::
BOSSBS-2158R-HRP
Beschreibung:
Functions as a calcium permeable cation channel involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. Together with TRPV4, forms mechano- and thermosensitive channels in cilium (PubMed:18695040). PKD1 and PKD2 may function through a common signaling pathway that is necessary for normal tubulogenesis. Acts as a regulator of cilium length, together with PKD1. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling. Also involved in left/right axis specification downstream of nodal flow: forms a complex with PKD1L1 in cilia to facilitate flow detection in left/right patterning (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12942R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12942R-A680
Lokale Artikelnummer::
BOSSBS-12942R-A680
Beschreibung:
All members of the Src gene family of tyrosine kinases are characterised by a carboxy terminal domain tyrosine which is highly phosphorylated in the inactive form of the enzyme and phosphorylated to a much lesser extent when the enzyme is active. In the case of Src p60, Y527 is this tyrosine; however, a mutant form of c-Src in which Y527 is replaced by phenylalanine is transforming and displays 5 to 10 fold elevated kinase activity compared to its normal counterpart. Csk has been identified as a Src-related tyrosine kinase having both SH2 and SH3 domains and a catalytic domain but lacking sequences amino terminal to the SH3 domain as well as carboxy terminal regulatory sequences. Csk phosphorylates Src on Y527 and also downregulates Lyn, Fyn and Lck by tyrosine phosphorylation of carboxy terminal regulatory sites.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12941R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12941R-HRP
Lokale Artikelnummer::
BOSSBS-12941R-HRP
Beschreibung:
All members of the Src gene family of tyrosine kinases are characterized by a carboxy terminal domain tyrosine which is highly phosphorylated in the inactive form of the enzyme and phosphorylated to a much lesser extent when the enzyme is active. In the case of Src p60, Y527 is this tyrosine; however, a mutant form of c-Src in which Y527 is replaced by phenylalanine is transforming and displays 5- to 10-fold elevated kinase activity compared to its normal counterpart. Csk has been identified as a Src-related tyrosine kinase having both SH2 and SH3 domains and a catalytic domain but lacking sequences amino terminal to the SH3 domain as well as carboxy terminal regulatory sequences. Csk phosphorylates Src on Y527 and also downregulates Lyn, Fyn and Lck by tyrosine phosphorylation of carboxy terminal regulatory sites.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12414R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12414R-A555
Lokale Artikelnummer::
BOSSBS-12414R-A555
Beschreibung:
MISR II is a 573 amino acid protein encoded by the human gene AMHR2. MISR II belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily and contains one protein kinase domain. Upon ligand binding, MISR II forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. These type II receptors rylate and activate type I receptors which autophosphorylate, then bind and activate Smad transcriptional regulators. MISR II also acts as a receptor for anti-Muellerian hormone. Defects in AMHR2 are the cause of persistent Muellerian duct syndrome type 2 (PMDS-2). PMDS-2 is a form of male pseudo-hermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males.
VE:
1 * 100 µl
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