L(-)-Glutathion+(oxidierte+Form)
Artikel-Nr:
(BOSSBS-4846R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4846R-FITC
Lokale Artikelnummer::
BOSSBS-4846R-FITC
Beschreibung:
Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4846R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4846R-A555
Lokale Artikelnummer::
BOSSBS-4846R-A555
Beschreibung:
Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3299R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3299R-A680
Lokale Artikelnummer::
BOSSBS-3299R-A680
Beschreibung:
E3 ubiquitin-protein ligase accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. This protein inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation. Furthermore, it promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5, and promotes the ubiquitination and degradation of SGK.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0205R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0205R-A750
Lokale Artikelnummer::
BOSSBS-0205R-A750
Beschreibung:
GHRF encoded by this gene belongs to the glucagon family and is a preproprotein that is produced in the hypothalamus. The preproprotein is cleaved to form a 44 aa factor, also called somatocrinin, that acts to stimulate growth hormone release from the pituitary. Variant receptors for somatocrinin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1812R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1812R-CY3
Lokale Artikelnummer::
BOSSBS-1812R-CY3
Beschreibung:
NOTCH3 functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBP-J kappa and activates genes of the enhancer of split locus. It affects the implementation of differentiation, proliferation and apoptotic programs. Defects in NOTCH3 are associated with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) (swissprot).
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
This antibody recognizes both the free and protein-conjugated (either soluble or cell bound) form of biotin. This MAb is highly specific to biotin and shows no cross-reaction with other structurally related compounds. It has a very high affinity for biotin and is excellent for use in various amplification techniques. In some applications, localization of biotinylated probes with avidin produces unacceptably high background staining. Anti-biotin antibody may be substituted to decrease this noise.
Artikel-Nr:
(BOSSBS-0205R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0205R-FITC
Lokale Artikelnummer::
BOSSBS-0205R-FITC
Beschreibung:
GHRF encoded by this gene belongs to the glucagon family and is a preproprotein that is produced in the hypothalamus. The preproprotein is cleaved to form a 44 aa factor, also called somatocrinin, that acts to stimulate growth hormone release from the pituitary. Variant receptors for somatocrinin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3299R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3299R-CY3
Lokale Artikelnummer::
BOSSBS-3299R-CY3
Beschreibung:
E3 ubiquitin-protein ligase accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. This protein inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation. Furthermore, it promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5, and promotes the ubiquitination and degradation of SGK.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9450R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9450R-A647
Lokale Artikelnummer::
BOSSBS-9450R-A647
Beschreibung:
Cytidine is a nucleoside formed by a cytosine attached to a ribose ring via a beta-N1-glycosidic bond. DNA is methylated on cytidines by DNA methylases (DNMTs)to generate 5-methylcytidine (5-mC), a potent epigenetics marker and regulator of gene expression. The reverse reaction (cytidine demethylation) starts with its oxidation to hydroxymethyl- (5-hmC), formyl- (5-fC), and carboxy- (5-caC) cytidine. Several enzymes, including the Tet family of proteins have been implicated in cytidine demethylation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5955R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5955R-CY7
Lokale Artikelnummer::
BOSSBS-5955R-CY7
Beschreibung:
This gene encodes a member of the Ras-association domain family (RASSF). Members of this family form the core of a highly conserved tumor suppressor network, the Salvador-Warts-Hippo (SWH) pathway. The protein encoded by this gene is a Ras effector protein that induces apoptosis. A genomic region containing this gene has been linked to susceptibility to viral bronchiolitis. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4209R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4209R-CY3
Lokale Artikelnummer::
BOSSBS-4209R-CY3
Beschreibung:
Cullin 2 is a member of the family of human Cullin genes (CUL1, 2, 3, 4a, 4b and 5) homologous to the S. cerevisiae cdc53 gene. It is a component of E3 ubiquitin ligase complexes, including the inactive transcriptional elongation complex SIII, which mediates the ubiquitination of hypoxia-inducible factor (HIF). SIII is formed by three subunits: Elongin C, Elongin B and VHL. Cullin 2 may serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13452R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13452R-FITC
Lokale Artikelnummer::
BOSSBS-13452R-FITC
Beschreibung:
The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity (By similarity). Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9450R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9450R-A350
Lokale Artikelnummer::
BOSSBS-9450R-A350
Beschreibung:
Cytidine is a nucleoside formed by a cytosine attached to a ribose ring via a beta-N1-glycosidic bond. DNA is methylated on cytidines by DNA methylases (DNMTs)to generate 5-methylcytidine (5-mC), a potent epigenetics marker and regulator of gene expression. The reverse reaction (cytidine demethylation) starts with its oxidation to hydroxymethyl- (5-hmC), formyl- (5-fC), and carboxy- (5-caC) cytidine. Several enzymes, including the Tet family of proteins have been implicated in cytidine demethylation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13263R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13263R-CY7
Lokale Artikelnummer::
BOSSBS-13263R-CY7
Beschreibung:
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma aminobutyric acid from L glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin dependent diabetes. This gene may also play a role in the stiff man syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4209R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4209R-CY5
Lokale Artikelnummer::
BOSSBS-4209R-CY5
Beschreibung:
Cullin 2 is a member of the family of human Cullin genes (CUL1, 2, 3, 4a, 4b and 5) homologous to the S. cerevisiae cdc53 gene. It is a component of E3 ubiquitin ligase complexes, including the inactive transcriptional elongation complex SIII, which mediates the ubiquitination of hypoxia-inducible factor (HIF). SIII is formed by three subunits: Elongin C, Elongin B and VHL. Cullin 2 may serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10369R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10369R-CY5
Lokale Artikelnummer::
BOSSBS-10369R-CY5
Beschreibung:
The protein encoded by this gene is secreted and then cleaved to form the 10 aa luteinizing hormone-releasing hormone (LHRH, also known as gonadoliberin-1), and prolactin release-inhibiting factor (also known as GnRH-associated peptide 1). LHRH stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutation in this gene are associated with hypogonadotropic hypogonadism. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2012].
VE:
1 * 100 µl
Preis auf Anfrage
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