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L(-)-Glutathion+(oxidierte+Form)
Artikel-Nr:
(BOSSBS-12908R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12908R-CY5
Lokale Artikelnummer::
BOSSBS-12908R-CY5
Beschreibung:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying protein. ZBTB44 is a 570 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB44 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB44 functions as a transcription regulator. Four isoforms of ZBTB44 have been identified.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7959R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7959R
Lokale Artikelnummer::
BOSSBS-7959R
Beschreibung:
The amphoterin-induced gene and ORF (AMIGO) family of proteins consists of AMIGO1, AMIGO2 and AMIGO3. All three members are single pass type I membrane proteins that contain several leucine-rich repeats, one IgG domain, and a transmembrane domain. The AMIGO proteins are specifically expressed on fiber tracts of neuronal tissues and participate in their formation. The AMIGO proteins can form complexes with each other, but can also bind itself. AMIGO1, also designated Alivin-2, promotes growth and fasciculation of neurites and plays a role in myelination and fasciculation of developing neural axons. In cerebellar neurons, AMIGO2 (Alivin-1) is crucial for depolarization-dependent survival. Similar to AMIGO1 and AMIGO2, AMIGO3 (Alivin-3) plays a role in homophilic and/or heterophilic cell-cell interaction and signal transduction.
VE:
1 * 100 µl
Artikel-Nr:
(111-1629)
Lieferant:
3M
Hersteller-Artikelnummer::
UF01014
Lokale Artikelnummer::
MMMAUF01014
Beschreibung:
Gehörschutzstöpsel mit Kabel aus einer patentierten Polymerformulierung, die bequeme dreifach geflanschte Spitze dieser Gehörschutzstöpsel bietet eine hervorragende Dämpfung von 35 dB SNR, eine der höchsten unter den vorgeformten Gehörschutzstöpseln. Die Ohrstöpsel sind bereits vorgeformt, um eine optimale Passform zu gewährleisten.
VE:
1 * 50 PAAR
Artikel-Nr:
(SIALN0786-15VL)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
N0786-15VL
Lokale Artikelnummer::
SIALN0786-15VL
Beschreibung:
β-Nicotinamid-Adenin-Dinucleotid Dinatriumsalz, reduzierte Form (NADH-Na₂), Sigma-Aldrich®
VE:
1 * 15 Vial
Artikel-Nr:
(SIALN7410-15VL)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
N7410-15VL
Lokale Artikelnummer::
SIALN7410-15VL
Beschreibung:
β-Nicotinamid-Adenin-Dinucleotid Dinatriumsalz, reduzierte Form (NADH-Na₂), Sigma-Aldrich®
VE:
1 * 15 Vial
Artikel-Nr:
(BOSSBS-5626R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5626R-A680
Lokale Artikelnummer::
BOSSBS-5626R-A680
Beschreibung:
The synucleins, including Alpha-synuclein (also designated NACP for nonamyloid component precursor),Beta-synuclein (also designated PNP 14 for neuroprotein 14)and Gamma-synuclein (also designated persyn or BCSG1 for breast cancer-specific gene 1)are presynaptic protein abundant in neurons. Alpha-synuclein, a component of Alzheimer?s disease amyloid plaques, is localised to neuronal cell bodies and synapses. Coordinate expression of Alpha-synucleinand Beta-synuclein may be important during hematopoetic cell differentiation. In patients with Parkinson?s disease, a mutant form of Alpha-synuclein has been found and Gamma-synuclein is associated with axonal pathology.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9895R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9895R-A680
Lokale Artikelnummer::
BOSSBS-9895R-A680
Beschreibung:
Biogenesis of lysosome-related organelles complex-1 (BLOC-1) is a multisubunit protein necessary for biogenesis of specialised organelles of the endosomal-lysosomal system (such as melanosomes and platelet-dense granules). The complex consists of coiled-coil-forming proteins Snapin, Pallidin, Cappuccino, Muted, BLOS1, BLOS2, and BLOS3. The localisation of these proteins varies as they can be cytoplasmic, peripheral membrane bound or anchored to the vesicular membrane.Cappuccino, a primarily cytoplasmic protein, plays a role in the development of melanosomes, platelet-dense granules and other lysosome-related organelles. It interacts primarily with pallidin and Muted and has been implicated as an actin-nucleation factor that may play a role in crosstalk between microfilaments and microtubules.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
This antibody recognizes a 63 kDa protein, which is identified as TOX3. It contains a high mobility group (HMG)-box, which regulates Ca2 -dependent transcription in neurons through interaction with the cAMP-response-element-binding protein (CREB). TOX3 appears to be associated with breast cancer susceptibility and is expressed downstream of a cytoprotective cascade together with CITED1, a transcriptional regulator that does not bind directly to DNA. TOX3 is predominantly expressed in the brain and forms homodimers. TOX3 overexpression protects neuronal cells from cell death caused by endoplasmic reticulum stress or BAX overexpression through the induction of anti-apoptotic transcripts and repression of pro-apoptotic transcripts.
Artikel-Nr:
(BOSSBS-0174R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0174R-HRP
Lokale Artikelnummer::
BOSSBS-0174R-HRP
Beschreibung:
The estrogen receptor (ER) is a 66 kDa protein that mediates the actions of estrogens in estrogen responsive tissues. It is a member of a large superfamily of nuclear hormone receptors that function as ligand activated transcription factors. The ER gene consists of more than 140 kb of genomic DNA divided into 8 exons. These translate into a protein with six functionally discrete domains, labeled A through F. A second form of the estrogen receptor, ER beta has recently been described. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti estrogen (e.g. tamoxifen) therapy.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4981R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4981R-HRP
Lokale Artikelnummer::
BOSSBS-4981R-HRP
Beschreibung:
HIV1 performs highly complex orchestrated tasks during the assembly, budding, maturation and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA. p55 is digested by HIV1 protease into intermediate products p41 and p15. p41 is further digested into matrix protein p17 and capsid protein p24. Likewise, p15 is further digested into nucleocapsid protein p7 and to p6 and p1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3452R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3452R-A680
Lokale Artikelnummer::
BOSSBS-3452R-A680
Beschreibung:
Rb is a tumor suppressor gene which functions as a negative regulator of the cell cycle by interacting with transcription factors including E2F1, PU1, ATF2, UBF, Elf1 and cAbl. This ability of Rb to alter transcription is regulated by phosphorylation catalysed by the cyclin dependent protein kinases (cdks). Rb is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus 16E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the Rb gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukaemia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5667R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5667R-A647
Lokale Artikelnummer::
BOSSBS-5667R-A647
Beschreibung:
Rb is a tumor suppressor gene which functions as a negative regulator of the cell cycle by interacting with transcription factors including E2F1, PU1, ATF2, UBF, Elf1 and cAbl. This ability of Rb to alter transcription is regulated by phosphorylation catalyzed by the cyclin dependent protein kinases (cdks). Rb is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus 16E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the Rb gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2605R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2605R-A680
Lokale Artikelnummer::
BOSSBS-2605R-A680
Beschreibung:
IL15RA is a cytokine receptor that specifically binds IL15 with high affinity. It shares two subunits with the receptor of IL2, the IL2R beta and IL2R gamma chains. This forms the basis of many overlapping biological activities of IL15 and IL2. The IL2 receptor requires an additional IL2-specific alpha subunit for high affinity IL2 binding. This protein is structurally related to IL2R alpha, but is capable of binding IL15 with high affinity independent of other subunits, which suggests the distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. There are nine different isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0174R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0174R-CY3
Lokale Artikelnummer::
BOSSBS-0174R-CY3
Beschreibung:
The estrogen receptor (ER) is a 66 kDa protein that mediates the actions of estrogens in estrogen responsive tissues. It is a member of a large superfamily of nuclear hormone receptors that function as ligand activated transcription factors. The ER gene consists of more than 140 kb of genomic DNA divided into 8 exons. These translate into a protein with six functionally discrete domains, labeled A through F. A second form of the estrogen receptor, ER beta has recently been described. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti estrogen (e.g. tamoxifen) therapy.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4104R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4104R-A555
Lokale Artikelnummer::
BOSSBS-4104R-A555
Beschreibung:
PLM (FXYD1)is a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. PLM may be phosphorylated by several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. It is thought to form an ion channel or regulate ion channel activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7098R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7098R-A350
Lokale Artikelnummer::
BOSSBS-7098R-A350
Beschreibung:
Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Promotes cell-surface expression of HRH3. Has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis. Could also promote endothelial cell proliferation and regulate endothelial morphogenesis.Tissue specificity: Detected in epithelial cells from colon, esophagus and kidney (at protein level). Expression is prominent in heart, kidney, placenta and skeletal muscle.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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