L(-)-Glutathion+(oxidierte+Form)
Artikel-Nr:
(BOSSBS-5230R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5230R-HRP
Lokale Artikelnummer::
BOSSBS-5230R-HRP
Beschreibung:
Bid, a BH3 domain containing proapoptotic Bcl2 family member, is localized in the cytosolic fraction of cells as an inactive precursor. Its active form is generated upon proteolytic cleavage by caspase 8 in the Fas signaling pathway. Cleaved Bid translocates to mitochondria and releases its potent proapoptotic activity, which in turn induces cytochrome c release and mitochondrial damage. The cytochrome c releasing activity of Bid was antagonized by Bcl2. Mutation in the SH3 domain can diminish the cytochrome c releasing activity. In animal model studies, Bid deficient mice are found resistant to the lethal effects of death factor signals relayed through Fas.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 12 kDa, identified as β-microglobulin. β-microglobulin non-covalently associates with the 44 kDa chain to form the HLA Class I antigen complex. Human β-2 microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes. This MAb is specific to human β-2 microglobulin and does not react with non-human primate cells. This antibody reacts with all cell types excluding erythrocytes. The detection of β-2 microglobulin in body fluids has been used as a tumor marker and for monitoring patients with HIV infection.
Artikel-Nr:
(BOSSBS-8388R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8388R-A680
Lokale Artikelnummer::
BOSSBS-8388R-A680
Beschreibung:
WD-repeats are motifs that are found in a variety of proteins and are characterised by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. WDR23 (WD-repeat-containing protein 23), also known as GL014 or PRO2389, is a 546 amino acid protein that contains seven WD-repeats. WDR23 is expressed as three isoforms due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1911R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1911R-FITC
Lokale Artikelnummer::
BOSSBS-1911R-FITC
Beschreibung:
Catalyzes the calcium-dependent formation of isopeptide cross-links between glutamine and lysine residues in various proteins, as well as the conjugation of polyamines to proteins. Involved in the formation of the cornified envelope (CE), a specialized component consisting of covalent cross-links of proteins beneath the plasma membrane of terminally differentiated keratinocytes. Catalyzes small proline-rich proteins (SPRR1 and SPRR2) and LOR cross-linking to form small interchain oligomers, which are further cross-linked by TGM1 onto the growing CE scaffold (By similarity). In hair follicles, involved in cross-linking structural proteins to hardening the inner root sheath.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8388R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8388R-CY7
Lokale Artikelnummer::
BOSSBS-8388R-CY7
Beschreibung:
WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. WDR23 (WD-repeat-containing protein 23), also known as GL014 or PRO2389, is a 546 amino acid protein that contains seven WD-repeats. WDR23 is expressed as three isoforms due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5626R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5626R-A488
Lokale Artikelnummer::
BOSSBS-5626R-A488
Beschreibung:
The synucleins, including Alpha-synuclein (also designated NACP for nonamyloid component precursor),Beta-synuclein (also designated PNP 14 for neuroprotein 14)and Gamma-synuclein (also designated persyn or BCSG1 for breast cancer-specific gene 1)are presynaptic protein abundant in neurons. Alpha-synuclein, a component of Alzheimer’s disease amyloid plaques, is localized to neuronal cell bodies and synapses. Coordinate expression of Alpha-synucleinand Beta-synuclein may be important during hematopoetic cell differentiation. In patients with Parkinson’s disease, a mutant form of Alpha-synuclein has been found and Gamma-synuclein is associated with axonal pathology.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11245R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11245R-A680
Lokale Artikelnummer::
BOSSBS-11245R-A680
Beschreibung:
Voltage-dependent Ca²⁺ channels mediate Ca²⁺ entry into excitable cells in response to membrane depolarisation, and they are involved in a variety of Ca²⁺ dependent processes, including muscle contraction, hormone or neurotransmitter release and gene expression. Ca²⁺ currents are characterised on the basis of their biophysical and pharmacologic properties and include L-, N-, T-, P-, Q-, and R- types. L-type Ca²⁺ currents initiate muscle contraction, endocrine secretion, and gene transcription, and can be regulated through second-messenger activated protein phosphorylation pathways. L-type calcium channels may form macromolecular Signalling complexes with G protein-coupled receptors, thereby enhancing the selectivity of regulating specific targets.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5230R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5230R-A647
Lokale Artikelnummer::
BOSSBS-5230R-A647
Beschreibung:
Bid, a BH3 domain containing proapoptotic Bcl2 family member, is localized in the cytosolic fraction of cells as an inactive precursor. Its active form is generated upon proteolytic cleavage by caspase 8 in the Fas signaling pathway. Cleaved Bid translocates to mitochondria and releases its potent proapoptotic activity, which in turn induces cytochrome c release and mitochondrial damage. The cytochrome c releasing activity of Bid was antagonized by Bcl2. Mutation in the SH3 domain can diminish the cytochrome c releasing activity. In animal model studies, Bid deficient mice are found resistant to the lethal effects of death factor signals relayed through Fas.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2806R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2806R-CY5.5
Lokale Artikelnummer::
BOSSBS-2806R-CY5.5
Beschreibung:
This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. [provided by RefSeq]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5230R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5230R-FITC
Lokale Artikelnummer::
BOSSBS-5230R-FITC
Beschreibung:
Bid, a BH3 domain containing proapoptotic Bcl2 family member, is localized in the cytosolic fraction of cells as an inactive precursor. Its active form is generated upon proteolytic cleavage by caspase 8 in the Fas signaling pathway. Cleaved Bid translocates to mitochondria and releases its potent proapoptotic activity, which in turn induces cytochrome c release and mitochondrial damage. The cytochrome c releasing activity of Bid was antagonized by Bcl2. Mutation in the SH3 domain can diminish the cytochrome c releasing activity. In animal model studies, Bid deficient mice are found resistant to the lethal effects of death factor signals relayed through Fas.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8388R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8388R-CY5.5
Lokale Artikelnummer::
BOSSBS-8388R-CY5.5
Beschreibung:
WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. WDR23 (WD-repeat-containing protein 23), also known as GL014 or PRO2389, is a 546 amino acid protein that contains seven WD-repeats. WDR23 is expressed as three isoforms due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(SIALN6785-10VL)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
N6785-10VL
Lokale Artikelnummer::
SIALN6785-10VL
Beschreibung:
β-Nicotinamid-Adenin-Dinucleotid Dinatriumsalz, reduzierte Form (NADH-Na₂), Sigma-Aldrich®
VE:
1 * 10 Vial
Lieferant:
Sigma-Aldrich
Beschreibung:
β-Nicotinamid-Adenin-Dinucleotid Dinatriumsalz, reduzierte Form (NADH-Na₂) Hydrat, Sigma-Aldrich®
Artikel-Nr:
(BOSSBS-0665R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0665R-A488
Lokale Artikelnummer::
BOSSBS-0665R-A488
Beschreibung:
Plays a central role during gametogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Directly binds methylated piRNAs, a class of 24 to 3 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. Besides their function in transposable elements repression, piRNAs are probably involved in other processes during meiosis such as translation regulation (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0665R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0665R-A350
Lokale Artikelnummer::
BOSSBS-0665R-A350
Beschreibung:
Plays a central role during gametogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Directly binds methylated piRNAs, a class of 24 to 3 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. Besides their function in transposable elements repression, piRNAs are probably involved in other processes during meiosis such as translation regulation (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1820R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1820R-HRP
Lokale Artikelnummer::
BOSSBS-1820R-HRP
Beschreibung:
High Mobility Group (HMG) proteins, a group of chromosomal proteins common to all eukaryotes, bind DNA in a non-sequence-specific fashion to promote chromatin function and gene regulation, helping with transcription, replication, recombination, and DNA repair. HMGB4 is HMG2-like, isoform 2, high-mobility group box 4. This gene can be found on Chromosome 1. HMGB4 contains two HMG-box regions, and is found in a variety of eukaryotic chromosomal proteins. HMGB proteins are phosphorylated to various extents. The existence of differentially modified forms increases the number of distinct HMGB protein variants in plant chromatin that may be adapted to certain functions.
VE:
1 * 100 µl
Preis auf Anfrage
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