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controlce
Korrigiert: "controlce"
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Artikel-Nr:
(BOSSBS-6637R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6637R-FITC
Lokale Artikelnummer::
BOSSBS-6637R-FITC
Beschreibung:
This gene has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The protein encoded by this gene contains six putative transmembrane domains and may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1693R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1693R-A680
Lokale Artikelnummer::
BOSSBS-1693R-A680
Beschreibung:
Calcium-binding protein that interacts with newly synthesised glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5005R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5005R-A647
Lokale Artikelnummer::
BOSSBS-5005R-A647
Beschreibung:
PFKFB2 is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. It has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. PFKFB2 regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. There are two named isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12528R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12528R-A680
Lokale Artikelnummer::
BOSSBS-12528R-A680
Beschreibung:
This gene encodes one of seven subunits of the human Arp2/3 protein complex. This complex controls actin polymerization in cells and has been conserved throughout eukaryotic evolution. This gene encodes the p20 subunit, which is necessary for actin nucleation and high-affinity binding to F-actin. Alternative splicing results in multiple transcript variants. Naturally occurring read-through transcription exists between this gene and the downstream tubulin tyrosine ligase-like family, member 3 (TTLL3), which results in the production of a fusion protein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1722R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1722R-A488
Lokale Artikelnummer::
BOSSBS-1722R-A488
Beschreibung:
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F3 binds specifically to RB1 in a cell-cycle dependent manner. Inhibits adipogenesis, probably through the repression of CEBPA binding to its target gene promoters (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6804R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6804R-HRP
Lokale Artikelnummer::
BOSSBS-6804R-HRP
Beschreibung:
This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15483R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15483R-A555
Lokale Artikelnummer::
BOSSBS-15483R-A555
Beschreibung:
HIBADH is a 336 amino acid mitochondrial enzyme that catalyses the NAD+-dependent, reversible oxidisation of 3-Hydroxyisobutyrate to methylmalonate semialdehyde, an intermediate of valine catabolism. The enzyme functions as a homodimer between a pH of 7,0 and 10,0, with optimal activity between 8,8 and 9,0. It was previously hypothesised that defects in the gene encoding HIBADH may be the cause of 3-Hydroxyisobutyric aciduria, a rare disorder that is characterised by a variety of clinical manifestations such as neurodevelopmental problems and dysmorphic features. However, it was shown that HIBADH activity was equal in patients with 3-Hydroxyisobutyric aciduria as compared with controls.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3472R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3472R-A750
Lokale Artikelnummer::
BOSSBS-3472R-A750
Beschreibung:
This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12528R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12528R-A750
Lokale Artikelnummer::
BOSSBS-12528R-A750
Beschreibung:
This gene encodes one of seven subunits of the human Arp2/3 protein complex. This complex controls actin polymerization in cells and has been conserved throughout eukaryotic evolution. This gene encodes the p20 subunit, which is necessary for actin nucleation and high-affinity binding to F-actin. Alternative splicing results in multiple transcript variants. Naturally occurring read-through transcription exists between this gene and the downstream tubulin tyrosine ligase-like family, member 3 (TTLL3), which results in the production of a fusion protein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6804R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6804R-A488
Lokale Artikelnummer::
BOSSBS-6804R-A488
Beschreibung:
This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11448R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11448R-FITC
Lokale Artikelnummer::
BOSSBS-11448R-FITC
Beschreibung:
Arylalkylamine N-acetyltransferase belongs to the superfamily of acetyltransferases. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for seasonal reproduction, modulates the function of the circadian clock in the suprachiasmatic nucleus, and influences activity and sleep. This enzyme is rapidly inactivated when animals are exposed to light at night. This protein is 80% identical to sheep and rat AA-NAT. Arylalkylamine N-acetyltransferase may contribute a multifactorial genetic diseases such as altered behavior in sleep/wake cycle.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3645R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3645R-A680
Lokale Artikelnummer::
BOSSBS-3645R-A680
Beschreibung:
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. At least four variants encoding the same protein have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(ABCAAB52130-7)
Lieferant:
Abcam
Hersteller-Artikelnummer::
AB52130-7
Lokale Artikelnummer::
ABCAAB52130-7
Beschreibung:
Anti-MUC2 Mouse monoclonal antibody [clone: SPM513]
VE:
1 * 7 mL
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(ABCAAB117864-100)
Lieferant:
Abcam
Hersteller-Artikelnummer::
AB117864-100
Lokale Artikelnummer::
ABCAAB117864-100
Beschreibung:
Anti-HHEX Mouse Monoclonal Antibody [clone: 3E6]
VE:
1 * 100 µl
This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(ABCAAB52562-100)
Lieferant:
Abcam
Hersteller-Artikelnummer::
AB52562-100
Lokale Artikelnummer::
ABCAAB52562-100
Beschreibung:
Anti-CCL5 Mouse Monoclonal Antibody [clone: VL1]
VE:
1 * 100 µG
This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(ABCAAB128107-100)
Lieferant:
Abcam
Hersteller-Artikelnummer::
AB128107-100
Lokale Artikelnummer::
ABCAAB128107-100
Beschreibung:
Anti-SAMHD1 Mouse Monoclonal Antibody [clone: 1A1]
VE:
1 * 100 µl
This is a MarketSource item. Additional charges may apply
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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