controlce
Artikel-Nr:
(BOSSBS-4136R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4136R-A647
Lokale Artikelnummer::
BOSSBS-4136R-A647
Beschreibung:
Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific, growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4110R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4110R-A488
Lokale Artikelnummer::
BOSSBS-4110R-A488
Beschreibung:
GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. Increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. Sequesters inactive non-tyrosine-phosphorylated paxillin in cytoplasmic complexes. Involved in the regulation of cytokinesis; the function may involve SDCCAG3 and PTPN13 (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0759R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0759R-A750
Lokale Artikelnummer::
BOSSBS-0759R-A750
Beschreibung:
Plays important roles in controlling the metabolism of fatty acids at differents levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyses the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis. Acts also as nuclear transcriptional coactivator for PPARGC1A/PPARA regulatory pathway to modulate lipid metabolism gene expression. Is involved in adipocyte differentiation. Isoform 1 is recruited at the mitochondrion outer membrane and is involved in mitochondrial fission by converting phosphatidic acid to diacylglycerol.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13478R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13478R-A647
Lokale Artikelnummer::
BOSSBS-13478R-A647
Beschreibung:
Human reproduction is controlled by the hypothalaic-pituitary gonadal axis laid down early in fetal development. Gonadotropin releasing hormone (GnRH), also known as GnRH-associated peptide, luteinizing hormone releasing hormone (LHRH), luliberin or gonadorelin, is a decapeptide that is an important molecule in the hypothalamic-pituitary-gonadal axis control circuit. GnRH is produced by hypothalamic neurons and secreted in a pulsatile manner into the capillary plexus of the medianeminence. GnRH affects the release of lutenizing hormone and follicle stimulating hormone from gonadotropic cells in the anterior pituitary. In addition to hypothalamic GnRH (GnRH I), a second GnRH form (GnRH II) functions primarily in the midbrain. GnRH is expressed in the acrosomal region of human sperm and in the anterior pituitary tissue and cancer cells. Unlike GnRH I, GnRH II is highly expressed outside the brain, particularly in the kidney, bone marrow and prostate, suggesting that it may have multiple functions. GnRH binds to a specific G protein-coupled receptor in the pituitary to regulate synthesis and secretion of gonadotropins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7913R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7913R-A488
Lokale Artikelnummer::
BOSSBS-7913R-A488
Beschreibung:
Negative regulator of YAP1 in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Acts as a tumor suppressor which plays a critical role in maintenance of ploidy through its actions in both mitotic progression and the G1 tetraploidy checkpoint. Negatively regulates G2/M transition by down-regulating CDK1 kinase activity. Involved in the control of p53 expression. Affects cytokinesis by regulating actin polymerization through negative modulation of LIMK1. May also play a role in endocrine function.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7913R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7913R-A750
Lokale Artikelnummer::
BOSSBS-7913R-A750
Beschreibung:
Negative regulator of YAP1 in the Hippo signaling pathway that plays a pivotal role in organ sise control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Acts as a tumor suppressor which plays a critical role in maintenance of ploidy through its actions in both mitotic progression and the G1 tetraploidy checkpoint. Negatively regulates G2/M transition by down-regulating CDK1 kinase activity. Involved in the control of p53 expression. Affects cytokinesis by regulating actin polymerisation through negative modulation of LIMK1. May also play a role in endocrine function.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5374R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5374R-HRP
Lokale Artikelnummer::
BOSSBS-5374R-HRP
Beschreibung:
GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. Increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. Sequesters inactive non-tyrosine-phosphorylated paxillin in cytoplasmic complexes. Involved in the regulation of cytokinesis; the function may involve SDCCAG3 and PTPN13 (By similarity).
VE:
1 * 100 µl
Lieferant:
OriGene
Hersteller-Artikelnummer::
SR302382
Lokale Artikelnummer::
ORIGSR302382
Beschreibung:
IL7 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 3574) Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml 1 * 1 KIT
VE:
1 * 1 KIT
Lieferant:
OriGene
Hersteller-Artikelnummer::
SR406314
Lokale Artikelnummer::
ORIGSR406314
Beschreibung:
Cacybp (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 12301) Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml 1 * 1 KIT
VE:
1 * 1 KIT
Lieferant:
OriGene
Hersteller-Artikelnummer::
SR309597
Lokale Artikelnummer::
ORIGSR309597
Beschreibung:
LEF1 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 51176) Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml 1 * 1 KIT
VE:
1 * 1 KIT
Lieferant:
OriGene
Hersteller-Artikelnummer::
SR423069
Lokale Artikelnummer::
ORIGSR423069
Beschreibung:
Lrp5 (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 16973) Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml 1 * 1 KIT
VE:
1 * 1 KIT
Lieferant:
OriGene
Hersteller-Artikelnummer::
SR304941
Lokale Artikelnummer::
ORIGSR304941
Beschreibung:
TRPC6 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 7225) Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml 1 * 1 KIT
VE:
1 * 1 KIT
Lieferant:
OriGene
Hersteller-Artikelnummer::
SR315339
Lokale Artikelnummer::
ORIGSR315339
Beschreibung:
DOCK11 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 139818) Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml 1 * 1 KIT
VE:
1 * 1 KIT
Lieferant:
OriGene
Hersteller-Artikelnummer::
SR407764
Lokale Artikelnummer::
ORIGSR407764
Beschreibung:
Lin28b (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 380669) Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml 1 * 1 KIT
VE:
1 * 1 KIT
Lieferant:
OriGene
Hersteller-Artikelnummer::
SR416457
Lokale Artikelnummer::
ORIGSR416457
Beschreibung:
Cdc25a (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 12530) Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml 1 * 1 KIT
VE:
1 * 1 KIT
Lieferant:
OriGene
Hersteller-Artikelnummer::
SR410874
Lokale Artikelnummer::
ORIGSR410874
Beschreibung:
Cdk6 (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 12571) Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml 1 * 1 KIT
VE:
1 * 1 KIT
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