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controlce
Korrigiert: "controlce"
Alternative Möglichkeiten:
Artikel-Nr:
(BOSSBS-4136R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4136R-FITC
Lokale Artikelnummer::
BOSSBS-4136R-FITC
Beschreibung:
Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific, growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9377R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9377R-A350
Lokale Artikelnummer::
BOSSBS-9377R-A350
Beschreibung:
Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4136R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4136R-A488
Lokale Artikelnummer::
BOSSBS-4136R-A488
Beschreibung:
Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific, growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3148R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3148R-A488
Lokale Artikelnummer::
BOSSBS-3148R-A488
Beschreibung:
Glycogen synthase kinase 3 (GSK3) is a proline directed serine threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase. GSK3 has been implicated in fundamental cell processes such as cell fate determination, metabolism, transcriptional control and oncogenesis. Two isoforms, alpha (GSK3A; OMIM 606784) and beta, show a high degree of amino acid homology within their catalytic domains. GSK3B is involved in energy metabolism, neuronal cell development and body pattern formation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4076R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4076R-A680
Lokale Artikelnummer::
BOSSBS-4076R-A680
Beschreibung:
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10490R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10490R-A647
Lokale Artikelnummer::
BOSSBS-10490R-A647
Beschreibung:
The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5705R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5705R-HRP
Lokale Artikelnummer::
BOSSBS-5705R-HRP
Beschreibung:
This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4076R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4076R-FITC
Lokale Artikelnummer::
BOSSBS-4076R-FITC
Beschreibung:
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4692R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4692R-A680
Lokale Artikelnummer::
BOSSBS-4692R-A680
Beschreibung:
Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), CTNNB1/beta-catenin, APC and AXIN1. Requires primed phosphorylation of the majority of its substrates. Contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. Regulates glycogen metabolism in liver, but not in muscle. May also mediate the development of insulin resistance by regulating activation of transcription factors. In Wnt signaling, regulates the level and transcriptional activity of nuclear CTNNB1/beta-catenin. Facilitates amyloid precursor protein (APP) processing and the generation of APP-derived amyloid plaques found in Alzheimer disease. May be involved in the regulation of replication in pancreatic beta-cells. Is necessary for the establishment of neuronal polarity and axon outgrowth. Through phosphorylation of the anti-apoptotic protein MCL1, may control cell apoptosis in response to growth factors deprivation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5501R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5501R-A680
Lokale Artikelnummer::
BOSSBS-5501R-A680
Beschreibung:
Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific, growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1155R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1155R-A647
Lokale Artikelnummer::
BOSSBS-1155R-A647
Beschreibung:
Transcription factor that controls transcriptional expression of its target genes by binding to the E box (5'-CANNTG-3'). Plays a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. Acts synergistically with FOXN4 to specify the identity of V2b neurons rather than V2a from bipotential p2 progenitors during spinal cord neurogenesis, probably through DLL4-NOTCH signaling activation. Essential for the generation of olfactory and autonomic neurons (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9377R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9377R-A750
Lokale Artikelnummer::
BOSSBS-9377R-A750
Beschreibung:
Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1155R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1155R-FITC
Lokale Artikelnummer::
BOSSBS-1155R-FITC
Beschreibung:
Transcription factor that controls transcriptional expression of its target genes by binding to the E box (5'-CANNTG-3'). Plays a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. Acts synergistically with FOXN4 to specify the identity of V2b neurons rather than V2a from bipotential p2 progenitors during spinal cord neurogenesis, probably through DLL4-NOTCH signaling activation. Essential for the generation of olfactory and autonomic neurons (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0760R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0760R-A350
Lokale Artikelnummer::
BOSSBS-0760R-A350
Beschreibung:
Plays important roles in controlling the metabolism of fatty acids at differents levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis. Acts also as nuclear transcriptional coactivator for PPARGC1A/PPARA regulatory pathway to modulate lipid metabolism gene expression. Is involved in adipocyte differentiation. Isoform 1 is recruited at the mitochondrion outer membrane and is involved in mitochondrial fission by converting phosphatidic acid to diacylglycerol.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4136R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4136R-HRP
Lokale Artikelnummer::
BOSSBS-4136R-HRP
Beschreibung:
Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific, growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1155R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1155R-A488
Lokale Artikelnummer::
BOSSBS-1155R-A488
Beschreibung:
Transcription factor that controls transcriptional expression of its target genes by binding to the E box (5'-CANNTG-3'). Plays a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. Acts synergistically with FOXN4 to specify the identity of V2b neurons rather than V2a from bipotential p2 progenitors during spinal cord neurogenesis, probably through DLL4-NOTCH signaling activation. Essential for the generation of olfactory and autonomic neurons (By similarity).
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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