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SARTORIUS BALANCES
Artikel-Nr:
(BOSSBS-9172R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9172R-A750
Lokale Artikelnummer::
BOSSBS-9172R-A750
Beschreibung:
The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5975R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5975R-A555
Lokale Artikelnummer::
BOSSBS-5975R-A555
Beschreibung:
SSX8 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11408R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11408R-A488
Lokale Artikelnummer::
BOSSBS-11408R-A488
Beschreibung:
MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11018R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11018R-A680
Lokale Artikelnummer::
BOSSBS-11018R-A680
Beschreibung:
This gene encodes a Golgi protein which is a member of the polypeptide N-acetylgalactosaminyltransferase (ppGalNAc-Ts) protein family. These enzymes catalyse the transfer of N-acetyl-D-galactosamine (GalNAc) to the hydroxyl groups on serines and threonines in target peptides. The encoded protein has been shown to transfer GalNAc to large proteins like mucins. Multiple transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3934R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3934R-A647
Lokale Artikelnummer::
BOSSBS-3934R-A647
Beschreibung:
Cytochrome C Oxidase subunits I, II and III form the functional core of the enzyme complex.Defects in Cytochrome C Oxidase subunits III are a cause of Leber hereditary optic neuropathy (LHON) and cytochrome c oxidase deficiency (COX deficiency). Defects in Cytochrome C Oxidase subunits III are also found in mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) syndrome and recurrent myoglobinuria.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13675R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13675R-A680
Lokale Artikelnummer::
BOSSBS-13675R-A680
Beschreibung:
B cell adaptor for phosphoinositide 3-kinase (BCAP) is a tyrosine kinase substrate that bridges B cell receptor (BCR) associated kinases to the PIK3 pathway. Syk, Btk or Lyn-dependent tyrosine phosphorylation of BCAP, provides binding sites for the p85 subunit of PIK3. BCAP mRNA is present in mouse spleen, thymus, liver, lung, macrophage and B cell lines. Human BCAP maps to chromosome 10q24.2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0136R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0136R-A555
Lokale Artikelnummer::
BOSSBS-0136R-A555
Beschreibung:
GTP cyclohydrolase I (also designated dopa-responsive dystonia) catalyzes the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphate, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis. Tetrahydrobiopterin is an essential cofactor for 3 aromatic amino acid monooxygenases: phenylalanine, tyrosine, and tryptophan hydroxylases. Animals can synthesize tetrahydrobiopterin in vivo from GTP through several enzymatic reactions.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3577R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3577R-A555
Lokale Artikelnummer::
BOSSBS-3577R-A555
Beschreibung:
Important in metal transport, in particular iron. Can also transport manganese, cobalt, cadmium, nickel, vanadium and lead. Involved in apical iron uptake into duodenal enterocytes. Involved in iron transport from acidified endosomes into the cytoplasm of erythroid precursor cells. May play an important role in hepatic iron accumulation and tissue iron distribution. May serve to import iron into the mitochondria.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13367R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13367R-A488
Lokale Artikelnummer::
BOSSBS-13367R-A488
Beschreibung:
This gene encodes a protein that is highly similar to the mouse cGMP-dependent protein kinase anchoring protein 42kDa. The mouse protein has been found to localize with the Golgi and recruit cGMP-dependent protein kinase I alpha to the Golgi in mouse testes. It is thought to play a role in germ cell development. Transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3177R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3177R-A647
Lokale Artikelnummer::
BOSSBS-3177R-A647
Beschreibung:
Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5861R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5861R-A647
Lokale Artikelnummer::
BOSSBS-5861R-A647
Beschreibung:
This gene encodes a secreted protein and member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) family. This protein lacks the metalloproteinase and disintegrin-like domains, which are typical of the ADAMTS family, but contains other ADAMTS domains, including the thrombospondin type 1 motif. This protein may have important functions in the extracellular matrix. Alternative splicing results in multiple transcript variants encoding distinct proteins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0179R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0179R-A350
Lokale Artikelnummer::
BOSSBS-0179R-A350
Beschreibung:
Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1243R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1243R-A488
Lokale Artikelnummer::
BOSSBS-1243R-A488
Beschreibung:
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor internalization (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11788R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11788R-A555
Lokale Artikelnummer::
BOSSBS-11788R-A555
Beschreibung:
The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6643R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6643R-A488
Lokale Artikelnummer::
BOSSBS-6643R-A488
Beschreibung:
Defects in GORAB are the cause of geroderma osteodysplasticum (GO) [MIM:231070]; also known as gerodermia osteodysplastica or Walt Disney dwarfism. GO is a rare autosomal recessive disorder characterized by lax, wrinkled skin, joint laxity and a typical face with a prematurely aged appearance. Skeletal signs include severe osteoporosis leading to frequent fractures, malar and mandibular hypoplasia and a variable degree of growth retardation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0132R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0132R-A647
Lokale Artikelnummer::
BOSSBS-0132R-A647
Beschreibung:
Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by a coronavirus, called SARS-associated coronavirus (SARS-CoV). Human coronaviruses (HCoVs) were previously only associated with mild diseases. The SARS-CoV genome contains five major open reading frames (ORFs) that encode the replicase polyprotein; the spike (S), envelope (E), and membrane (M) glycoproteins; and the nucleocapsid protein (N).
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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