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DIAGNOSTIC SYSTEMS DIASYS
Artikel-Nr:
(BOSSBS-2162R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2162R-HRP
Lokale Artikelnummer::
BOSSBS-2162R-HRP
Beschreibung:
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5786R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5786R-FITC
Lokale Artikelnummer::
BOSSBS-5786R-FITC
Beschreibung:
Kallistatin is a serine proteinase inhibitor which binds to tissue kallikrein and inhibits its amidolytic and kininogenase activity. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein. Heparin blocks kallistatin's complex formation with tissue kallikrein and abolishes its inhibitory effect on tissue kallikrein's activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7769R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7769R-A555
Lokale Artikelnummer::
BOSSBS-7769R-A555
Beschreibung:
SEPT1 is a member of the septin family of GTPases. Members of this family are required for cytokinesis. SEPT1 is associated with the tau-based paired helical filament core, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2483R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2483R-A750
Lokale Artikelnummer::
BOSSBS-2483R-A750
Beschreibung:
Chemotactic for resting T-lymphocytes, and eosinophils. Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Binds to CCR3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2483R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2483R-A680
Lokale Artikelnummer::
BOSSBS-2483R-A680
Beschreibung:
Chemotactic for resting T-lymphocytes, and eosinophils. Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Binds to CCR3.
VE:
1 * 100 µl
Artikel-Nr:
(732-2590)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
AB-1800/W
Lokale Artikelnummer::
ADVAAB-1800/W
Beschreibung:
VersiPlates comprise strips of eight tubes linked to each other forming the familiar 12×8 or 96-well ANSI/SBS format. The small tear points between strips enable a single strip or as many as required for the individual experiment to be separated.
VE:
1 * 25 ST
Artikel-Nr:
(BOSSBS-4117R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4117R-A350
Lokale Artikelnummer::
BOSSBS-4117R-A350
Beschreibung:
Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin. Appears be required for postnatal control of vascular regression in the eye. Required for posterior patterning of the epiblast during gastrulation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6465R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6465R-A647
Lokale Artikelnummer::
BOSSBS-6465R-A647
Beschreibung:
Plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation. Enhances phosphoinositide 3-kinase (PI3K)-dependent phosphorylation and kinase activity of AKT1/PKB, but does not possess kinase activity itself. Phosphorylation of AKT1/PKB thereby induces the phosphorylation of downstream effectors GSK3 and FOXO1/FKHR, and regulates DNA replication and cell proliferation (By similarity). Essential for the integrity of the actin cytoskeleton and for cell migration. Required for formation of actin stress fibers and lamellipodia. May be involved in membrane sorting in the early endosome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6090R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6090R-CY5
Lokale Artikelnummer::
BOSSBS-6090R-CY5
Beschreibung:
RBM5 (RNA binding motif protein 5) is a nuclear SR related RNA binding protein which specifically binds poly(G) RNA homopolymers in vitro. It modulates both apoptosis and the cell cycle, and retards tumor formation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5089R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5089R-A680
Lokale Artikelnummer::
BOSSBS-5089R-A680
Beschreibung:
Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5089R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5089R-A750
Lokale Artikelnummer::
BOSSBS-5089R-A750
Beschreibung:
Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0985R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0985R-CY5
Lokale Artikelnummer::
BOSSBS-0985R-CY5
Beschreibung:
Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP). May play a central role in tooth enamel formation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0985R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0985R-CY5.5
Lokale Artikelnummer::
BOSSBS-0985R-CY5.5
Beschreibung:
Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP). May play a central role in tooth enamel formation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6090R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6090R-A750
Lokale Artikelnummer::
BOSSBS-6090R-A750
Beschreibung:
RBM5 (RNA binding motif protein 5) is a nuclear SR related RNA binding protein which specifically binds poly(G) RNA homopolymers <i>in vitro</i>. It modulates both apoptosis and the cell cycle, and retards tumor formation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7836R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7836R-A750
Lokale Artikelnummer::
BOSSBS-7836R-A750
Beschreibung:
Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organisation during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11051R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11051R-CY7
Lokale Artikelnummer::
BOSSBS-11051R-CY7
Beschreibung:
HAPLN2 is a 340 amino acid protein encoded by the human gene HAPLN2. HAPLN2 belongs to the HAPLN family and contains one immunoglobulin (Ig)-like, V-type domain and two link domains. HAPLN2 mediates a firm binding of versican V2 to hyaluronic acid. HAPLN2 is believed to play a pivotal role in the formation of the hyaluronan-associated matrix in the central nervous system (CNS), which facilitates neuronal conduction and general structural stabilization. HAPLN2 may also be involved in the formation of extracellular matrices, contributing to perineuronal nets and facilitating the understanding of a functional role of these extracellular matrices. HAPLN2 is found in several nuclei throughout the midbrain and hindbrain in a perineuronal net pattern.
VE:
1 * 100 µl
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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