2',3',4'-Trihydroxyacetophenon
Lieferant:
Biotium
Beschreibung:
CD90 (Thy-1) is an 18-35 kDa GPI-anchored plasma membrane glycoprotein expressed in many cell types, such as in hematopoietic cells and neurons, connective tissues, various fibroblast and stromal cell lines, tumor endothelial cell lines and others. It is involved in T-cell activation, cellular adhesion, proliferation and migration, neurite outgrowth, wound healing, apoptosis, and fibrosis. CD90 participates in multiple signaling cascades and its effects are tissue- and cell type-specific. It often functions as an important regulator of cell-cell and cell-matrix interactions.
Artikel-Nr:
(BOSSBS-12919R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12919R-A750
Lokale Artikelnummer::
BOSSBS-12919R-A750
Beschreibung:
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2 -independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
Artikel-Nr:
(BOSSBS-10410R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10410R-A750
Lokale Artikelnummer::
BOSSBS-10410R-A750
Beschreibung:
Chemerin, also known as retinoic acid receptor responder 2 (RARRES2) and tazarotene induced gene 2 (TIG2), is a chemoattractant protein for cells expressing G-protein-linked receptor chemokine-like receptor 1 (CMKLR1, ChemR23 or GPCR-DEZ). The protein is synthesised as a secreted precursor, prochemerin (18 kDa), which is poorly active. Upon proteolytic removal of the last six amino acids, prochemerin is converted into mature active chemerin (15 to 16 kDa) that acts as a strong and highly specific agonist of its receptor CMKLR1. Chemerin is a newly described adipokine with effects on adipocyte differentiation and metabolism.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12919R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12919R-A350
Lokale Artikelnummer::
BOSSBS-12919R-A350
Beschreibung:
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012].
VE:
1 * 100 µl
Artikel-Nr:
(APOSOR12918-100MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR12918-100MG
Lokale Artikelnummer::
APOSOR12918-100MG
Beschreibung:
3-[(Pyridin-3-yl)methyl]piperidine-3-carboxylic acid, N-BOC protected
VE:
1 * 100 mg
Lieferant:
Thermo Scientific
Beschreibung:
(4-Methoxyphenyl)essigsäureethylester 97%
Artikel-Nr:
(FLUO023689-1G)
Lieferant:
FLUOROCHEM
Hersteller-Artikelnummer::
023689-1G
Lokale Artikelnummer::
FLUO023689-1G
Beschreibung:
1,8-Naphthyridin-2-carbonsäure Monohydrat
VE:
1 * 1 g
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Artikel-Nr:
(SIAL235334-25G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
235334-25G
Lokale Artikelnummer::
SIAL235334-25G
Beschreibung:
3,6-Dithia-1,8-octandiol, Sigma-Aldrich®
VE:
1 * 25 g
Artikel-Nr:
(BOSSBS-8098R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8098R-CY3
Lokale Artikelnummer::
BOSSBS-8098R-CY3
Beschreibung:
The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC34 (coiled-coil domain containing 34), also known as Renal carcinoma antigen NY-REN-41, is a 373 amino acid protein that is expressed in testis, breast, lung, placenta, liver and small intestine. A translocation between the short arms of chromosomes 11 and 18 affecting the CCDC34 gene has been identified in a patient with hamartoma of the retinal pigment epithelium. There are two isoforms of CCDC34 that are produced as a result of alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12302R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12302R-A488
Lokale Artikelnummer::
BOSSBS-12302R-A488
Beschreibung:
PHC1 is a 1,004 amino acid nuclear protein that is a component of the PcG multiprotein PRC1 complex. Specifically, the PcG PRC1 complex modifies histones, remodels chromatin and mediates monoubiquination of Histone H2A. Other constituent proteins involved in the PcG PRC1 complex are Mel-18, Bmi-1, M33, MPc2, MPc3, RING1, Ring1b, as well as several others. Existing as a homodimer, PHC1 contains one FCS-type zinc finger and a SAM (sterile alpha motif) domain. PHC1 is encoded by a gene located on human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8098R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8098R
Lokale Artikelnummer::
BOSSBS-8098R
Beschreibung:
The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC34 (coiled-coil domain containing 34), also known as Renal carcinoma antigen NY-REN-41, is a 373 amino acid protein that is expressed in testis, breast, lung, placenta, liver and small intestine. A translocation between the short arms of chromosomes 11 and 18 affecting the CCDC34 gene has been identified in a patient with hamartoma of the retinal pigment epithelium. There are two isoforms of CCDC34 that are produced as a result of alternative splicing events.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Folinic acid calcium salt ≥97,5%
Artikel-Nr:
(BOSSBS-7013R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7013R-A680
Lokale Artikelnummer::
BOSSBS-7013R-A680
Beschreibung:
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This gene appears not to be involved in this type of chromosome translocation. Two transcript variants encoding distinct isoforms have been identified for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3614R-PE)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3614R-PE
Lokale Artikelnummer::
BOSSBS-3614R-PE
Beschreibung:
Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3614R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3614R-CY5
Lokale Artikelnummer::
BOSSBS-3614R-CY5
Beschreibung:
Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.
VE:
1 * 100 µl
Preis auf Anfrage
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