Methyl+trans-3-hydroxycyclobutanecarboxylate
Artikel-Nr:
(BOSSBS-13487R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13487R-A555
Lokale Artikelnummer::
BOSSBS-13487R-A555
Beschreibung:
Golgin 245 is also known as p230, GCP2, GOLG or golgi autoantigen and is a 2,230 amino acid protein that is expressed as three isoforms. Golgin 245 is localized to the cytoplasm in cells and is a member of the golgin family, all of which are peripheral membrane proteins associated with the Golgi complex. Golgin 245 has a carboxyl-terminal GRIP domain, which attaches to the trans-Golgi network (TGN) and TGN-derived vesicles. It is thought that the interaction that takes place between golgin 245 and MACF1, which cross-links microtubules to the Actin cytoskeleton, allows proteins to be transported from the TGN to the cell periphery. against golgin 245 are associated with two chronic disorders known as Sjé°ƒren's syndrome and Hepatitis B.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11687R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11687R-A680
Lokale Artikelnummer::
BOSSBS-11687R-A680
Beschreibung:
PCSK1N is a 260 amino acid protein that is both secreted and localised to the trans-Golgi network. Expressed in pancreas and brain, PCSK1N is thought to play a role in the control of the neuroendocrine secretory pathway and may also be involved in PCSK1 inhibition. The gene encoding PCSK1N maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination, as an X and a Y chromosome lead to normal male development, while two copies of an X chromosome lead to normal female development. There are a number of conditions related to an abnormal number and combination of sex chromosomes, some of which include Turner's syndrome, color blindness, hemophilia and Duchenne muscular dystrophy.
VE:
1 * 100 µl
Artikel-Nr:
(BSENM-1815-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
M-1815-100
Lokale Artikelnummer::
BSENM-1815-100
Beschreibung:
Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth (By similarity). Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins (PubMed:10926528, PubMed:12044163, PubMed:11972040, PubMed:16908857, PubMed:16586416, PubMed:17060607, PubMed:17449675, PubMed:18818650, PubMed:21389983, PubMed:22198838, PubMed:23579341, PubMed:25205354, PubMed:27458239). Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (PubMed:1396673, PubMed:15111114). Ref: uniprot.org
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-4173R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4173R-A750
Lokale Artikelnummer::
BOSSBS-4173R-A750
Beschreibung:
TWIST1 and TWIST2 are basic helix-loop-helix transcriptional repressors that bind to E boxes in gene promoters, acting as master regulators in a variety of biological processes, including organogenesis, osteogenesis, cancer progression and hematopoietic cell development. Both TWIST1 and TWIST2 are found to act as Homodimers or Heterodimers with another bHLH protein. TWIST1 Acts as a transcriptional regulator. Inhibits myogenesis by sequestrating E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through physical interaction. TWIST1 also represses expression of proinflammatory cytokines such as TNFA and IL1B. TWIST2 inhibits transcriptional activation by MYOD1, MYOG, MEF2A, and MEF2C. Twist2 inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13487R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13487R-CY7
Lokale Artikelnummer::
BOSSBS-13487R-CY7
Beschreibung:
Golgin 245 is also known as p230, GCP2, GOLG or golgi autoantigen and is a 2,230 amino acid protein that is expressed as three isoforms. Golgin 245 is localized to the cytoplasm in cells and is a member of the golgin family, all of which are peripheral membrane proteins associated with the Golgi complex. Golgin 245 has a carboxyl-terminal GRIP domain, which attaches to the trans-Golgi network (TGN) and TGN-derived vesicles. It is thought that the interaction that takes place between golgin 245 and MACF1, which cross-links microtubules to the Actin cytoskeleton, allows proteins to be transported from the TGN to the cell periphery. against golgin 245 are associated with two chronic disorders known as Sjé°ƒren's syndrome and Hepatitis B.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13487R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13487R-A350
Lokale Artikelnummer::
BOSSBS-13487R-A350
Beschreibung:
Golgin 245 is also known as p230, GCP2, GOLG or golgi autoantigen and is a 2,230 amino acid protein that is expressed as three isoforms. Golgin 245 is localized to the cytoplasm in cells and is a member of the golgin family, all of which are peripheral membrane proteins associated with the Golgi complex. Golgin 245 has a carboxyl-terminal GRIP domain, which attaches to the trans-Golgi network (TGN) and TGN-derived vesicles. It is thought that the interaction that takes place between golgin 245 and MACF1, which cross-links microtubules to the Actin cytoskeleton, allows proteins to be transported from the TGN to the cell periphery. against golgin 245 are associated with two chronic disorders known as Sjé°ƒren's syndrome and Hepatitis B.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11785R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11785R-A488
Lokale Artikelnummer::
BOSSBS-11785R-A488
Beschreibung:
Maspardin is a 308 amino acid cytoplasmic protein that is widely expressed. Belonging to the AB hydrolase superfamily, Maspardin colocalizes with CD4 on endosomal/trans-Golgi network. It is thought that Maspardin may act as a negative regulatory factor in CD4-dependent T-cell activation. Defects in the gene encoding Maspardin are the result of hereditary spastic paraplegia autosomal recessive type 21 (also designated Mast syndrome), an autosomal recessive neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. The gene encoding Maspardin is encoded by human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2969R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2969R-A647
Lokale Artikelnummer::
BOSSBS-2969R-A647
Beschreibung:
E7 protein has both transforming and trans-activating activities. Disrupts the function of host retinoblastoma protein RB1/pRb, which is a key regulator of the cell cycle. Induces the disassembly of the E2F1 transcription factors from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. Interferes with histone deacetylation mediated by HDAC1 and HDAC2, leading to activation of transcription (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2441R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2441R-CY5.5
Lokale Artikelnummer::
BOSSBS-2441R-CY5.5
Beschreibung:
Acts as a transcriptional regulator. Inhibits myogenesis by sequestrating E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through physical interaction. This interaction probably involves the basic domains of both proteins. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Regulates cranial suture patterning and fusion. Activates transcription as a heterodimer with E proteins. Regulates gene expression differentially, depending on dimer composition. Homodimers induce expression of FGFR2 and POSTN while heterodimers repress FGFR2 and POSTN expression and induce THBS1 expression. Heterodimerization is also required for osteoblast differentiation. Represses the activity of the circadian transcriptional activator: NPAS2-ARNTL/BMAL1 heterodimer (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11270R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11270R-A555
Lokale Artikelnummer::
BOSSBS-11270R-A555
Beschreibung:
HSP56 is a cis-trans prolyl isomerase belonging to the immunophilin protein family. The human HSP 56 gene (FKBP4) has multiple polyadenylation sites and the HSP 56 protein can undergo phosphorylation. HSP 56 influences immunoregulatory gene expression in lymphocytes, protein folding and trafficking. It can serve as a co-chaperone for steroid hormone nuclear receptors to govern appropriate hormone action in target tissues. The protein can associate with phytanoyl-CoA alpha-hydroxylase (PHYH) and with HSP90 through a series of tetratricopeptide repeat (TPR) domains. HSP 56 is a TRPC ion channel accessory protein that modulates channel activation following receptor stimulation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11270R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11270R-FITC
Lokale Artikelnummer::
BOSSBS-11270R-FITC
Beschreibung:
HSP56 is a cis-trans prolyl isomerase belonging to the immunophilin protein family. The human HSP 56 gene (FKBP4) has multiple polyadenylation sites and the HSP 56 protein can undergo phosphorylation. HSP 56 influences immunoregulatory gene expression in lymphocytes, protein folding and trafficking. It can serve as a co-chaperone for steroid hormone nuclear receptors to govern appropriate hormone action in target tissues. The protein can associate with phytanoyl-CoA alpha-hydroxylase (PHYH) and with HSP90 through a series of tetratricopeptide repeat (TPR) domains. HSP 56 is a TRPC ion channel accessory protein that modulates channel activation following receptor stimulation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2441R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2441R-FITC
Lokale Artikelnummer::
BOSSBS-2441R-FITC
Beschreibung:
Acts as a transcriptional regulator. Inhibits myogenesis by sequestrating E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through physical interaction. This interaction probably involves the basic domains of both proteins. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Regulates cranial suture patterning and fusion. Activates transcription as a heterodimer with E proteins. Regulates gene expression differentially, depending on dimer composition. Homodimers induce expression of FGFR2 and POSTN while heterodimers repress FGFR2 and POSTN expression and induce THBS1 expression. Heterodimerization is also required for osteoblast differentiation. Represses the activity of the circadian transcriptional activator: NPAS2-ARNTL/BMAL1 heterodimer (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13454R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13454R-A750
Lokale Artikelnummer::
BOSSBS-13454R-A750
Beschreibung:
GMEB-1 is a 573 amino acid protein that contains one SAND domain and is a member of the KDWK family of combinatorial transcription modulators. Localized to both the cytoplasm and the nucleus, GMEB-1 forms a heterodimer with GMEB-2 (Glucocorticoid modulatory element-binding protein 2) and, once associated with GMEB-2, plays a key role in parvovirus DNA replication. In addition, GMEB-1 functions alone as a trans-acting factor that, by binding to glucocorticoid modulatory elements (GMEs) in TAT (tyrosine aminotransferase) promoters, increases intracellular sensitivity to glucocorticoid concentrations. GMEB-1 also interacts with initiator procaspases and, via this interaction, can inhibit caspase-induced apoptosis. Due to alternative splicing events, GMEB-1 is expressed as two isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13454R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13454R-CY7
Lokale Artikelnummer::
BOSSBS-13454R-CY7
Beschreibung:
GMEB-1 is a 573 amino acid protein that contains one SAND domain and is a member of the KDWK family of combinatorial transcription modulators. Localized to both the cytoplasm and the nucleus, GMEB-1 forms a heterodimer with GMEB-2 (Glucocorticoid modulatory element-binding protein 2) and, once associated with GMEB-2, plays a key role in parvovirus DNA replication. In addition, GMEB-1 functions alone as a trans-acting factor that, by binding to glucocorticoid modulatory elements (GMEs) in TAT (tyrosine aminotransferase) promoters, increases intracellular sensitivity to glucocorticoid concentrations. GMEB-1 also interacts with initiator procaspases and, via this interaction, can inhibit caspase-induced apoptosis. Due to alternative splicing events, GMEB-1 is expressed as two isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(SIALD134104-100G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
D134104-100G
Lokale Artikelnummer::
SIALD134104-100G
Beschreibung:
2,5-Dihydro-2,5-dimethoxyfuran (Gemisch der cis- und trans-Isomeren), Sigma-Aldrich®
VE:
1 * 100 g
Lieferant:
Sigma-Aldrich
Beschreibung:
trans2-Undecenal, Sigma-Aldrich®
Preis auf Anfrage
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