Suche >
4,4-Dimethylcyclohexa-1,5-dienylborons\u00E4ure+Mononatriumsalz
Drucken
Sie suchten nach:
54 015 results were found
4,4-Dimethylcyclohexa-1,5-dienylborons\u00E4ure+Mononatriumsalz
Artikel-Nr:
(BOSSBS-2370R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2370R-A350
Lokale Artikelnummer::
BOSSBS-2370R-A350
Beschreibung:
This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus.[provided by RefSeq, Feb 2011].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0126R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0126R-A488
Lokale Artikelnummer::
BOSSBS-0126R-A488
Beschreibung:
In cooperation with other chaperones, Hsp7s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11462R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11462R-A350
Lokale Artikelnummer::
BOSSBS-11462R-A350
Beschreibung:
NaBC1 is a protein found amplified in most breast carcinoma forms. It is expressed primarily as a cytoplasmic, detergent-stable homodimer that has a tendency to interact with DYNLL1 (PIN) and DYNLL2. Breast tumor lines that exhibit 20q13.2 gene amplification express much higher levels of the protein as compared to the levels found in other breast cancer lines that do not overexpress the NaBC1 mRNA. However, this upregulation does not affect growth rate or anchoring abilities of a cell, indicating the oncogenic properties of NaBC1 differ from that of other oncogenes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5673R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5673R-A488
Lokale Artikelnummer::
BOSSBS-5673R-A488
Beschreibung:
This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7554R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7554R-A488
Lokale Artikelnummer::
BOSSBS-7554R-A488
Beschreibung:
Eph receptor A2 is the receptor for members of the ephrin-A family. It binds to ephrin-A1, -A3, -A4 and -A5. Eph receptor A3 is also a receptor for members of the ephrin-A family. It binds to ephrin-A2, -A3, -A4 and -A5 and is thought to play a role in lymphoid function. Eph receptor A4 is a receptor for members of the ephrin-A family. It binds to ephrin-A1, -A4 and -A5. It binds more poorly to ephrin-A2 and -A3. It may play a role in a signal transduction process involved in hindbrain pattern formation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0081R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0081R-A350
Lokale Artikelnummer::
BOSSBS-0081R-A350
Beschreibung:
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4165R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4165R-A488
Lokale Artikelnummer::
BOSSBS-4165R-A488
Beschreibung:
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 4p16. This protein, in addition to binding Ca2+, also binds Zn2+ and Mg2+. This protein may play a role in the etiology of prostate cancer. [provided by RefSeq]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5272R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5272R-A555
Lokale Artikelnummer::
BOSSBS-5272R-A555
Beschreibung:
MRG15 ia a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis and DNA repair.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8034R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8034R-A488
Lokale Artikelnummer::
BOSSBS-8034R-A488
Beschreibung:
Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation. Down-regulates NF-kappa-B activity. Down-regulates SOD1 activity by interfering with its homodimerization. Plays a role in copper ion homeostasis. Can bind one copper ion per monomer. May function to facilitate biliary copper excretion within hepatocytes.Tissue specificity:Ubiquitous. Highest expression in the liver, with lower expression in brain, lung, placenta, pancreas, small intestine, heart, skeletal muscle, kidney and placenta.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4726R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4726R-A350
Lokale Artikelnummer::
BOSSBS-4726R-A350
Beschreibung:
Gross cystic disease is a common premenopausal disorder in which gross cysts are the predominant pathologic lesion. It is characterized by production of a fluid secretion which accumulates in the breast cysts. Gross cystic disease fluid is a pathologic secretion from breast composed of several glycoproteins, including a unique 15 kDa monomer protein, GCDFP 15. The cells within the body that produce GCDFP 15 appear to be restricted primarily to those with apocrine function. Studies have found GCDFP 15 to be a highly specific and sensitive marker for breast cancer.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1723R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1723R-A488
Lokale Artikelnummer::
BOSSBS-1723R-A488
Beschreibung:
Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15483R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15483R-A488
Lokale Artikelnummer::
BOSSBS-15483R-A488
Beschreibung:
HIBADH is a 336 amino acid mitochondrial enzyme that catalyses the NAD+-dependent, reversible oxidisation of 3-Hydroxyisobutyrate to methylmalonate semialdehyde, an intermediate of valine catabolism. The enzyme functions as a homodimer between a pH of 7,0 and 10,0, with optimal activity between 8,8 and 9,0. It was previously hypothesised that defects in the gene encoding HIBADH may be the cause of 3-Hydroxyisobutyric aciduria, a rare disorder that is characterised by a variety of clinical manifestations such as neurodevelopmental problems and dysmorphic features. However, it was shown that HIBADH activity was equal in patients with 3-Hydroxyisobutyric aciduria as compared with controls.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13181R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13181R-A488
Lokale Artikelnummer::
BOSSBS-13181R-A488
Beschreibung:
This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3; boomerang dysplasia; autosomal dominant Larsen syndrome; and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Nov 2009].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3587R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3587R-A350
Lokale Artikelnummer::
BOSSBS-3587R-A350
Beschreibung:
Tnk1 is a nonreceptor protein tyrosine kinase (NRPTK) and a new member of the Ack family of NRPTKs. Tnk1 is a ubiquitously expressed 47-kDa protein with autotyrosine kinase activity that is developmentally regulated during embryogenesis. Tnk1 is also upregulated following IL3 withdrawal from factor-dependent murine NSF/N1.H7 cells that undergo apoptosis, suggesting a role in growth inhibition. Data support a negative regulatory role for Tnk1 in regulating the Ras-Raf1-MAPK growth pathway by a mechanism that requires its autotyrosine kinase activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9302R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9302R-A350
Lokale Artikelnummer::
BOSSBS-9302R-A350
Beschreibung:
Spo11 is a type II topoisomerase that is thought to generate the chromosome breaks that initiate meiotic recombination. The Spo11 protein initiates meiotic recombination by generating DNA double-strand breaks (DSBs) and is required for meiotic synapsis in S. cerevisiae. The DSBs are located mostly in promoter regions, where the chromatin is in an open configuration, and cluster in domains along the chromosome. Expression of the Spo11 is detected mainly in the testis, in agreement with its predicted function in the initiation of meiotic recombination. Disruption of Spo11 leads to severe gonadal abnormalities from defective meiosis and results in infertility.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10288R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10288R-A555
Lokale Artikelnummer::
BOSSBS-10288R-A555
Beschreibung:
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520).
VE:
1 * 100 µl
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
Dieses Produkt ist nicht mehr verfügbar. Bitte kontaktieren Sie den VWR Kundenservice.
|
|||||||||
Listenansicht
