2-(3-Chloro-4-fluoroanilino)acetohydrazide
Artikel-Nr:
(BOSSBS-1926R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1926R-A555
Lokale Artikelnummer::
BOSSBS-1926R-A555
Beschreibung:
UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11924R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11924R-A750
Lokale Artikelnummer::
BOSSBS-11924R-A750
Beschreibung:
The protein tyrosine phosphatase (PTP) family of proteins are Signalling molecules that regulate processes such as cell growth, cell differentiation, oncogenic transformation and the mitotic cycle. PCPTP1, also known as PTPRR (Receptor-type tyrosine-protein phosphatase R), ECPTP, PTPBR7 or PTPRQ, is a 657 amino acid protein that functions to sequester inactive mitogen-activated protein kinases (MAPKs) to the cytoplasm. Expressed primarily in the brain with weaker expression in other parts of the body, PCPTP1 is a receptor-like molecule that is able to dephosphorylate MAPKs, thereby rendering them inactive. Three isoforms of PCPTP1 exist and are designated alpha, beta and gamma. The alpha form is localised to the cell membrane, while the beta and gamma forms are localised to the perinuclear areas within the cytoplasm.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6934R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6934R-A488
Lokale Artikelnummer::
BOSSBS-6934R-A488
Beschreibung:
May play an important role in the regulation of lymphoma cell growth. Interacts with a 16-kDa Leu-13 protein to form a complex possibly involved in signal transduction. May act as the viral receptor for HCV.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7947R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7947R-A750
Lokale Artikelnummer::
BOSSBS-7947R-A750
Beschreibung:
Abhydrolase domain containing 3 (ABHD3) belongs to the AB hydrolase superfamily. It has a central core predicted to form alpha/beta hydrolase folds and has a ser-ala-his catalytic triad characteristic of peroxidases.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7947R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7947R-A647
Lokale Artikelnummer::
BOSSBS-7947R-A647
Beschreibung:
Abhydrolase domain containing 3 (ABHD3) belongs to the AB hydrolase superfamily. It has a central core predicted to form alpha/beta hydrolase folds and has a ser-ala-his catalytic triad characteristic of peroxidases.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5004R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5004R-A680
Lokale Artikelnummer::
BOSSBS-5004R-A680
Beschreibung:
PFKFB1 belongs to the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. It forms a homodimer that is involved in both the synthesis and degradation of fructose 2,6-bisphosphate. The activity of this enzyme is thought to regulate glucose homeostasis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1558R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1558R-A555
Lokale Artikelnummer::
BOSSBS-1558R-A555
Beschreibung:
Stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12941R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12941R-A350
Lokale Artikelnummer::
BOSSBS-12941R-A350
Beschreibung:
All members of the Src gene family of tyrosine kinases are characterized by a carboxy terminal domain tyrosine which is highly phosphorylated in the inactive form of the enzyme and phosphorylated to a much lesser extent when the enzyme is active. In the case of Src p60, Y527 is this tyrosine; however, a mutant form of c-Src in which Y527 is replaced by phenylalanine is transforming and displays 5- to 10-fold elevated kinase activity compared to its normal counterpart. Csk has been identified as a Src-related tyrosine kinase having both SH2 and SH3 domains and a catalytic domain but lacking sequences amino terminal to the SH3 domain as well as carboxy terminal regulatory sequences. Csk phosphorylates Src on Y527 and also downregulates Lyn, Fyn and Lck by tyrosine phosphorylation of carboxy terminal regulatory sites.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3451R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3451R-CY3
Lokale Artikelnummer::
BOSSBS-3451R-CY3
Beschreibung:
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromsome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia.
VE:
1 * 100 µl
Artikel-Nr:
(BSENR-1838-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
R-1838-100
Lokale Artikelnummer::
BSENR-1838-100
Beschreibung:
The green fluorescent protein (GFP) is a 27 kDa protein isolated originally from the jellyfish Aequoria victoria. It has an endogenous fluorochrome activity with excitation maximum at 395nm and emission maximum at 509 nm, which is similar to that of fluorescein. GFP can be expressed in fluorescent form in essentially any prokaryotic or eukaryotic cell.
This GFP rabbit antibody was made against a recombinant GFP construct originating from an Aequoria species which was engineered to improve spectral properties and prevent oligomerization (1). This form of GFP, referred to as AcGFP, is 94% identical to the eGFP developed by Tsien and co-workers. The antibody can be used to verify the expression, size and stability of both AcGFP and eGFP fusion proteins in western blotting experiments and to amplify GFP signals in tissues of transgenic animals.
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-2158R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2158R-CY5.5
Lokale Artikelnummer::
BOSSBS-2158R-CY5.5
Beschreibung:
Functions as a calcium permeable cation channel involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. Together with TRPV4, forms mechano- and thermosensitive channels in cilium (PubMed:18695040). PKD1 and PKD2 may function through a common signaling pathway that is necessary for normal tubulogenesis. Acts as a regulator of cilium length, together with PKD1. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling. Also involved in left/right axis specification downstream of nodal flow: forms a complex with PKD1L1 in cilia to facilitate flow detection in left/right patterning (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12941R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12941R-CY7
Lokale Artikelnummer::
BOSSBS-12941R-CY7
Beschreibung:
All members of the Src gene family of tyrosine kinases are characterized by a carboxy terminal domain tyrosine which is highly phosphorylated in the inactive form of the enzyme and phosphorylated to a much lesser extent when the enzyme is active. In the case of Src p60, Y527 is this tyrosine; however, a mutant form of c-Src in which Y527 is replaced by phenylalanine is transforming and displays 5- to 10-fold elevated kinase activity compared to its normal counterpart. Csk has been identified as a Src-related tyrosine kinase having both SH2 and SH3 domains and a catalytic domain but lacking sequences amino terminal to the SH3 domain as well as carboxy terminal regulatory sequences. Csk phosphorylates Src on Y527 and also downregulates Lyn, Fyn and Lck by tyrosine phosphorylation of carboxy terminal regulatory sites.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2668R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2668R-A750
Lokale Artikelnummer::
BOSSBS-2668R-A750
Beschreibung:
Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2723R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2723R-CY3
Lokale Artikelnummer::
BOSSBS-2723R-CY3
Beschreibung:
May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9452R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9452R-CY3
Lokale Artikelnummer::
BOSSBS-9452R-CY3
Beschreibung:
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7741R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7741R-CY5
Lokale Artikelnummer::
BOSSBS-7741R-CY5
Beschreibung:
Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements.
VE:
1 * 100 µl
Preis auf Anfrage
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